siRNA blocking of mammalian target of rapamycin (mTOR) attenuates pathology in annonacin-induced tauopathy in mice
Tauopathy is a pathological hallmark of many neurodegenerative diseases. It is characterized by abnormal aggregates of pathological phosphotau and somatodendritic redistribution. One suggested strategy for treating tauopathy is to stimulate autophagy, hence, getting rid of these pathological protein...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English English English |
| Published: |
Springer Nature Switzerland AG
2019
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/67119/ http://irep.iium.edu.my/67119/ http://irep.iium.edu.my/67119/ http://irep.iium.edu.my/67119/1/mTOR.pdf http://irep.iium.edu.my/67119/7/67119_siRNA%20Blocking%20of%20Mammalian%20Target%20of%20Rapamycin%20%28mTOR%29%20Attenuates%20Pathology%20in%20Annonacin-Induced%20Tauopathy%20in%20Mice_wos.pdf http://irep.iium.edu.my/67119/13/67119_siRNA%20Blocking%20of%20Mammalian%20Target%20of%20Rapamycin%20mTOR_scopus.pdf |