Comparison of serum specific IgE with skin prick test in the diagnosis of allergy in Malaysia

We compared a newer serum specific IgE (SSIgE) test with skin prick testing (SPT) in the diagnosis of allergy in Malaysia. Ninety newly diagnosed allergic patients were enrolled for both tests. Using SPT as a clinical gold standard,the sensitivity, specificity, positive, and negative predictive v...

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Main Authors:	Asha'ari, Zamzil Amin, Yusof, Suhaimi, Yusof, Rosnida Azura, Ismail, Rushdan, CYC, Maraina
Format:	Article
Language:	English
Published:	Malaysian Medical Associations 2011
Subjects:	RF Otorhinolaryngology
Online Access:	http://irep.iium.edu.my/6730/ http://irep.iium.edu.my/6730/ http://irep.iium.edu.my/6730/1/Skin_prick_test_MJM.pdf

id	iium-6730
recordtype	eprints
spelling	iium-67302011-12-12T04:34:49Z http://irep.iium.edu.my/6730/ Comparison of serum specific IgE with skin prick test in the diagnosis of allergy in Malaysia Asha'ari, Zamzil Amin Yusof, Suhaimi Yusof, Rosnida Azura Ismail, Rushdan CYC, Maraina RF Otorhinolaryngology We compared a newer serum specific IgE (SSIgE) test with skin prick testing (SPT) in the diagnosis of allergy in Malaysia. Ninety newly diagnosed allergic patients were enrolled for both tests. Using SPT as a clinical gold standard,the sensitivity, specificity, positive, and negative predictive values (PPV, NPV) were calculated for SSIgE for each of the common allergens tested. The highest positive results for both SPT and SSIgE were for house dust mite and cat. Compared to SPT, SSIgE showed better sensitivity but poorer specificity, low PPV and good NPV in all the allergens tested. Significant positive correlation was seen between the diameter of wheal and flare of SPT and the SSIgE results. Malaysian Medical Associations 2011-08 Article PeerReviewed application/pdf en http://irep.iium.edu.my/6730/1/Skin_prick_test_MJM.pdf Asha'ari, Zamzil Amin and Yusof, Suhaimi and Yusof, Rosnida Azura and Ismail, Rushdan and CYC, Maraina (2011) Comparison of serum specific IgE with skin prick test in the diagnosis of allergy in Malaysia. Medical Journal of Malaysia, 66 (3). pp. 202-206. ISSN 0300-5283 http://www.e-mjm.org
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RF Otorhinolaryngology
spellingShingle	RF Otorhinolaryngology Asha'ari, Zamzil Amin Yusof, Suhaimi Yusof, Rosnida Azura Ismail, Rushdan CYC, Maraina Comparison of serum specific IgE with skin prick test in the diagnosis of allergy in Malaysia
description	We compared a newer serum specific IgE (SSIgE) test with skin prick testing (SPT) in the diagnosis of allergy in Malaysia. Ninety newly diagnosed allergic patients were enrolled for both tests. Using SPT as a clinical gold standard,the sensitivity, specificity, positive, and negative predictive values (PPV, NPV) were calculated for SSIgE for each of the common allergens tested. The highest positive results for both SPT and SSIgE were for house dust mite and cat. Compared to SPT, SSIgE showed better sensitivity but poorer specificity, low PPV and good NPV in all the allergens tested. Significant positive correlation was seen between the diameter of wheal and flare of SPT and the SSIgE results.
format	Article
author	Asha'ari, Zamzil Amin Yusof, Suhaimi Yusof, Rosnida Azura Ismail, Rushdan CYC, Maraina
author_facet	Asha'ari, Zamzil Amin Yusof, Suhaimi Yusof, Rosnida Azura Ismail, Rushdan CYC, Maraina
author_sort	Asha'ari, Zamzil Amin
title	Comparison of serum specific IgE with skin prick test in the diagnosis of allergy in Malaysia
title_short	Comparison of serum specific IgE with skin prick test in the diagnosis of allergy in Malaysia
title_full	Comparison of serum specific IgE with skin prick test in the diagnosis of allergy in Malaysia
title_fullStr	Comparison of serum specific IgE with skin prick test in the diagnosis of allergy in Malaysia
title_full_unstemmed	Comparison of serum specific IgE with skin prick test in the diagnosis of allergy in Malaysia
title_sort	comparison of serum specific ige with skin prick test in the diagnosis of allergy in malaysia
publisher	Malaysian Medical Associations
publishDate	2011
url	http://irep.iium.edu.my/6730/ http://irep.iium.edu.my/6730/ http://irep.iium.edu.my/6730/1/Skin_prick_test_MJM.pdf
first_indexed	2023-09-18T20:15:51Z
last_indexed	2023-09-18T20:15:51Z
_version_	1777407781938135040

Comparison of serum specific IgE with skin prick test in the diagnosis of allergy in Malaysia

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