Effects of Eurycoma longifolia jack (Tongkat Ali) alcoholic root extract against oral pathogens

Introduction: Eurycoma longifolia jack (E.L) is a herbal medicinal plant of South-East Asian origin, popularly recognized as ‘Tongkat Ali.’ The plant roots have been scientifically proven to have many biological effects including antibacterial activity however, no previous research to date has studi...

Full description

Bibliographic Details
Main Authors:	Alloha, Irani, Aziz, Nurul Ain Liyana, Faisal, Ghasak Ghazi, Arzmi, Mohd Hafiz, Abllah, Zurainie
Format:	Conference or Workshop Item
Language:	English English
Published:	2018
Subjects:	RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works
Online Access:	http://irep.iium.edu.my/67837/ http://irep.iium.edu.my/67837/19/67837%20abstract%20book.pdf http://irep.iium.edu.my/67837/3/POSTER%20IRANI%20YANA.pdf

id	iium-67837
recordtype	eprints
spelling	iium-678372018-11-30T03:14:56Z http://irep.iium.edu.my/67837/ Effects of Eurycoma longifolia jack (Tongkat Ali) alcoholic root extract against oral pathogens Alloha, Irani Aziz, Nurul Ain Liyana Faisal, Ghasak Ghazi Arzmi, Mohd Hafiz Abllah, Zurainie RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works Introduction: Eurycoma longifolia jack (E.L) is a herbal medicinal plant of South-East Asian origin, popularly recognized as ‘Tongkat Ali.’ The plant roots have been scientifically proven to have many biological effects including antibacterial activity however, no previous research to date has studied the effect on oral pathogens including cariogenic bacteria.This study was done to determine the antibacterial and antifungal activities of E.L. root extract against three common oral pathogens. Material and Methods: The microorganisms used were Candida albicans, Streptococcus mutans and Lactobacillus casei.: E.L root was extracted using soxhlet method. Disc diffusion assay was conducted using extract concentration of 200mg/ml. Nystatin and Ampicillin were used as positive control for fungal and bacterial tests respectively. Minimum Inhibitory Concentration (MIC) was done to determine the lowest inhibitory concentration of the extract on the microorganisms. Results: E.L extract inhibited the growth of Candida albicans and Streptococcus mutans at a concentration of 200mg/ml with a zone of inhibition of 16.0 ± 3.0mm and 7.0 ± 1.0mm respectively. There was no antimicrobial effect of the extract on Lactobacillus casei. The MIC of E.L extract against both Candida albicans and Streptococcus mutans was 25mg/ml. Conclusions: The results from this study revealed the potential use of Eurycoma longifolia jack as an antimicrobial agent which can be used to produce new oral care products. 2018 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/67837/19/67837%20abstract%20book.pdf application/pdf en http://irep.iium.edu.my/67837/3/POSTER%20IRANI%20YANA.pdf Alloha, Irani and Aziz, Nurul Ain Liyana and Faisal, Ghasak Ghazi and Arzmi, Mohd Hafiz and Abllah, Zurainie (2018) Effects of Eurycoma longifolia jack (Tongkat Ali) alcoholic root extract against oral pathogens. In: 7th Dental Students Scientific Conference 2018 (DSSC), 26 February 2018, Kuantan, Pahang. (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works
spellingShingle	RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works Alloha, Irani Aziz, Nurul Ain Liyana Faisal, Ghasak Ghazi Arzmi, Mohd Hafiz Abllah, Zurainie Effects of Eurycoma longifolia jack (Tongkat Ali) alcoholic root extract against oral pathogens
description	Introduction: Eurycoma longifolia jack (E.L) is a herbal medicinal plant of South-East Asian origin, popularly recognized as ‘Tongkat Ali.’ The plant roots have been scientifically proven to have many biological effects including antibacterial activity however, no previous research to date has studied the effect on oral pathogens including cariogenic bacteria.This study was done to determine the antibacterial and antifungal activities of E.L. root extract against three common oral pathogens. Material and Methods: The microorganisms used were Candida albicans, Streptococcus mutans and Lactobacillus casei.: E.L root was extracted using soxhlet method. Disc diffusion assay was conducted using extract concentration of 200mg/ml. Nystatin and Ampicillin were used as positive control for fungal and bacterial tests respectively. Minimum Inhibitory Concentration (MIC) was done to determine the lowest inhibitory concentration of the extract on the microorganisms. Results: E.L extract inhibited the growth of Candida albicans and Streptococcus mutans at a concentration of 200mg/ml with a zone of inhibition of 16.0 ± 3.0mm and 7.0 ± 1.0mm respectively. There was no antimicrobial effect of the extract on Lactobacillus casei. The MIC of E.L extract against both Candida albicans and Streptococcus mutans was 25mg/ml. Conclusions: The results from this study revealed the potential use of Eurycoma longifolia jack as an antimicrobial agent which can be used to produce new oral care products.
format	Conference or Workshop Item
author	Alloha, Irani Aziz, Nurul Ain Liyana Faisal, Ghasak Ghazi Arzmi, Mohd Hafiz Abllah, Zurainie
author_facet	Alloha, Irani Aziz, Nurul Ain Liyana Faisal, Ghasak Ghazi Arzmi, Mohd Hafiz Abllah, Zurainie
author_sort	Alloha, Irani
title	Effects of Eurycoma longifolia jack (Tongkat Ali) alcoholic root extract against oral pathogens
title_short	Effects of Eurycoma longifolia jack (Tongkat Ali) alcoholic root extract against oral pathogens
title_full	Effects of Eurycoma longifolia jack (Tongkat Ali) alcoholic root extract against oral pathogens
title_fullStr	Effects of Eurycoma longifolia jack (Tongkat Ali) alcoholic root extract against oral pathogens
title_full_unstemmed	Effects of Eurycoma longifolia jack (Tongkat Ali) alcoholic root extract against oral pathogens
title_sort	effects of eurycoma longifolia jack (tongkat ali) alcoholic root extract against oral pathogens
publishDate	2018
url	http://irep.iium.edu.my/67837/ http://irep.iium.edu.my/67837/19/67837%20abstract%20book.pdf http://irep.iium.edu.my/67837/3/POSTER%20IRANI%20YANA.pdf
first_indexed	2023-09-18T21:36:19Z
last_indexed	2023-09-18T21:36:19Z
_version_	1777412844579454976

Effects of Eurycoma longifolia jack (Tongkat Ali) alcoholic root extract against oral pathogens

Similar Items