Anticancer activity of acetogenins from Annona muricata fruit

Medicinal plants become very important in our days for their therapeutic benefits to humankind. It sustains human health, and it is commonly known as herbal medicines since ancient times. Annona muricata is a heart-shaped fruit that is consumed raw or as the fruit juice in the tropical area. A. mu...

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Main Authors:	Daddiouaissa, Djabir, Amid, Azura
Format:	Article
Language:	English English English
Published:	IIUM Press 2018
Subjects:	TP248.13 Biotechnology
Online Access:	http://irep.iium.edu.my/68372/ http://irep.iium.edu.my/68372/8/68372_Anticancer%20activity%20of%20acetogenins%20from%20Annona%20muricata%20fruit_ARTICLE.pdf http://irep.iium.edu.my/68372/7/68372_Anticancer%20activity%20of%20acetogenins%20from%20Annona%20muricata%20fruit_SCOPUS.pdf http://irep.iium.edu.my/68372/19/68372%20Anticancer%20Activity%20of%20Acetogenins%20from%20Annona%20Muricata%20Fruit%20WOS.pdf

id	iium-68372
recordtype	eprints
spelling	iium-683722019-01-27T07:13:14Z http://irep.iium.edu.my/68372/ Anticancer activity of acetogenins from Annona muricata fruit Daddiouaissa, Djabir Amid, Azura TP248.13 Biotechnology Medicinal plants become very important in our days for their therapeutic benefits to humankind. It sustains human health, and it is commonly known as herbal medicines since ancient times. Annona muricata is a heart-shaped fruit that is consumed raw or as the fruit juice in the tropical area. A. muricata is used in traditional and alternative medicine to treat different ailments such as diabetes, hypertension, respiratory and skin illness, inflammation and cancer. A. muricata contains essential anticancer agents named acetogenins that play the significant role in various cancer types. Acetogenins are strong nicotinamide adenine dinucleotide oxidase inhibitors of the cancer cell's mitochondrial membrane but showed neurotoxic effects in rats. Therefore, acetogenins need to be further investigated to determine the exact mechanisms of action, long-term safety, optimal dosage, and potential side effects. Given the extensive studies on A. muricata, this review focuses on the phytochemistry, medicinal uses, biological activities and the mechanisms of action for the fruit extracts and acetogenins, to stimulate further studies on the fruit pulp used for human consumption. IIUM Press 2018 Article PeerReviewed application/pdf en http://irep.iium.edu.my/68372/8/68372_Anticancer%20activity%20of%20acetogenins%20from%20Annona%20muricata%20fruit_ARTICLE.pdf application/pdf en http://irep.iium.edu.my/68372/7/68372_Anticancer%20activity%20of%20acetogenins%20from%20Annona%20muricata%20fruit_SCOPUS.pdf application/pdf en http://irep.iium.edu.my/68372/19/68372%20Anticancer%20Activity%20of%20Acetogenins%20from%20Annona%20Muricata%20Fruit%20WOS.pdf Daddiouaissa, Djabir and Amid, Azura (2018) Anticancer activity of acetogenins from Annona muricata fruit. International Medical Journal Malaysia, 17 (3). pp. 103-112. ISSN 1823-4631 E-ISSN 1823-4631
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	TP248.13 Biotechnology
spellingShingle	TP248.13 Biotechnology Daddiouaissa, Djabir Amid, Azura Anticancer activity of acetogenins from Annona muricata fruit
description	Medicinal plants become very important in our days for their therapeutic benefits to humankind. It sustains human health, and it is commonly known as herbal medicines since ancient times. Annona muricata is a heart-shaped fruit that is consumed raw or as the fruit juice in the tropical area. A. muricata is used in traditional and alternative medicine to treat different ailments such as diabetes, hypertension, respiratory and skin illness, inflammation and cancer. A. muricata contains essential anticancer agents named acetogenins that play the significant role in various cancer types. Acetogenins are strong nicotinamide adenine dinucleotide oxidase inhibitors of the cancer cell's mitochondrial membrane but showed neurotoxic effects in rats. Therefore, acetogenins need to be further investigated to determine the exact mechanisms of action, long-term safety, optimal dosage, and potential side effects. Given the extensive studies on A. muricata, this review focuses on the phytochemistry, medicinal uses, biological activities and the mechanisms of action for the fruit extracts and acetogenins, to stimulate further studies on the fruit pulp used for human consumption.
format	Article
author	Daddiouaissa, Djabir Amid, Azura
author_facet	Daddiouaissa, Djabir Amid, Azura
author_sort	Daddiouaissa, Djabir
title	Anticancer activity of acetogenins from Annona muricata fruit
title_short	Anticancer activity of acetogenins from Annona muricata fruit
title_full	Anticancer activity of acetogenins from Annona muricata fruit
title_fullStr	Anticancer activity of acetogenins from Annona muricata fruit
title_full_unstemmed	Anticancer activity of acetogenins from Annona muricata fruit
title_sort	anticancer activity of acetogenins from annona muricata fruit
publisher	IIUM Press
publishDate	2018
url	http://irep.iium.edu.my/68372/ http://irep.iium.edu.my/68372/8/68372_Anticancer%20activity%20of%20acetogenins%20from%20Annona%20muricata%20fruit_ARTICLE.pdf http://irep.iium.edu.my/68372/7/68372_Anticancer%20activity%20of%20acetogenins%20from%20Annona%20muricata%20fruit_SCOPUS.pdf http://irep.iium.edu.my/68372/19/68372%20Anticancer%20Activity%20of%20Acetogenins%20from%20Annona%20Muricata%20Fruit%20WOS.pdf
first_indexed	2023-09-18T21:37:02Z
last_indexed	2023-09-18T21:37:02Z
_version_	1777412889862209536

Anticancer activity of acetogenins from Annona muricata fruit

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