Prevalence of thyroid disorders in pregnant women in Hospital Tengku Ampuan Afzan & International Islamic University Malaysia Medical Centre

Introduction: Data on the burden of thyroid disease in pregnant women in our community is scarce albeit the detrimental effects it brought to both the mother and fetus if left untreated. The aim of this study was to determine the prevalence of thyroid disorders, socio-demography distribution, and me...

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Main Authors:	mohd Azemi, Nurul Azyati, Zainal Abidin, Nur Afirah, Mohd Amin, Adlina Nadhirah, Daraup, Salmi, Zakaria, Miza Hiryanti, Shahar, Mohammad Arif
Format:	Article
Language:	English
Published:	Kulliyyah of Medicine, International Islamic University Malaysia 2018
Subjects:	R Medicine (General) RC Internal medicine RC648 Specialties of Internal Medicine-Diseases of The Endocrine Glands. Clinical Endocrinology
Online Access:	http://irep.iium.edu.my/68716/ http://irep.iium.edu.my/68716/ http://irep.iium.edu.my/68716/1/Prevalence%20of%20thyroid%20disorders%20in%20pregnancy.pdf

id	iium-68716
recordtype	eprints
spelling	iium-687162018-12-24T08:22:53Z http://irep.iium.edu.my/68716/ Prevalence of thyroid disorders in pregnant women in Hospital Tengku Ampuan Afzan & International Islamic University Malaysia Medical Centre mohd Azemi, Nurul Azyati Zainal Abidin, Nur Afirah Mohd Amin, Adlina Nadhirah Daraup, Salmi Zakaria, Miza Hiryanti Shahar, Mohammad Arif R Medicine (General) RC Internal medicine RC648 Specialties of Internal Medicine-Diseases of The Endocrine Glands. Clinical Endocrinology Introduction: Data on the burden of thyroid disease in pregnant women in our community is scarce albeit the detrimental effects it brought to both the mother and fetus if left untreated. The aim of this study was to determine the prevalence of thyroid disorders, socio-demography distribution, and method of diagnosis in pregnant women of both tertiary centres in Kuantan, Pahang. Materials and Methods: A retrospective cross sectional study involving patients under follow ups at the Endocrine and Obstetric Clinics of Hospital Tengku Ampuan Afzan (HTAA) and International Islamic University Malaysia Medical Center (IIUM MC) from the 1st January until the 30th June 2017. Out of 923 pregnant women, 29 were found to have thyroid disorders. Detailed demographic data and thyroid function test readings were taken from their medical records and thyroid status were determined from TSH and FT4 readings using the trimester-specific thyroid reference range. Results: The prevalence of thyroid disorders in both centres was 3.14%, with specific prevalence of 2.80% for HTAA and 6.12% for IIUM MC. Nearly half of them were hyperthyroid (47.85%), 17.4% was hypothyroid and Graves’ disease dominated the diagnosis of thyroid disease (30.43%). Significant association was found in weight changes with patients’ thyroid status; reduction in weight in first trimester and increment in weight in second trimester were mainly seen in the hyperthyroid group (p<0.01, p=0.027). Conclusion: The acceptable prevalence of 3.14% for thyroid disorders in pregnancy could be contributed by the iodine availability in this community. High prevalence of Graves’ disease warrants future screening for maternal thyroid stimulating immunoglobulin amongst hyperthyroid women. Kulliyyah of Medicine, International Islamic University Malaysia 2018-12 Article PeerReviewed application/pdf en http://irep.iium.edu.my/68716/1/Prevalence%20of%20thyroid%20disorders%20in%20pregnancy.pdf mohd Azemi, Nurul Azyati and Zainal Abidin, Nur Afirah and Mohd Amin, Adlina Nadhirah and Daraup, Salmi and Zakaria, Miza Hiryanti and Shahar, Mohammad Arif (2018) Prevalence of thyroid disorders in pregnant women in Hospital Tengku Ampuan Afzan & International Islamic University Malaysia Medical Centre. International Medical Journal Malaysia, 17 (Supplementary 1). p. 53. E-ISSN 1823-4631 http://iiumedic.net/imjm/v1/download/vol_17_no_3_supp_1/MRS2018-54.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	R Medicine (General) RC Internal medicine RC648 Specialties of Internal Medicine-Diseases of The Endocrine Glands. Clinical Endocrinology
spellingShingle	R Medicine (General) RC Internal medicine RC648 Specialties of Internal Medicine-Diseases of The Endocrine Glands. Clinical Endocrinology mohd Azemi, Nurul Azyati Zainal Abidin, Nur Afirah Mohd Amin, Adlina Nadhirah Daraup, Salmi Zakaria, Miza Hiryanti Shahar, Mohammad Arif Prevalence of thyroid disorders in pregnant women in Hospital Tengku Ampuan Afzan & International Islamic University Malaysia Medical Centre
description	Introduction: Data on the burden of thyroid disease in pregnant women in our community is scarce albeit the detrimental effects it brought to both the mother and fetus if left untreated. The aim of this study was to determine the prevalence of thyroid disorders, socio-demography distribution, and method of diagnosis in pregnant women of both tertiary centres in Kuantan, Pahang. Materials and Methods: A retrospective cross sectional study involving patients under follow ups at the Endocrine and Obstetric Clinics of Hospital Tengku Ampuan Afzan (HTAA) and International Islamic University Malaysia Medical Center (IIUM MC) from the 1st January until the 30th June 2017. Out of 923 pregnant women, 29 were found to have thyroid disorders. Detailed demographic data and thyroid function test readings were taken from their medical records and thyroid status were determined from TSH and FT4 readings using the trimester-specific thyroid reference range. Results: The prevalence of thyroid disorders in both centres was 3.14%, with specific prevalence of 2.80% for HTAA and 6.12% for IIUM MC. Nearly half of them were hyperthyroid (47.85%), 17.4% was hypothyroid and Graves’ disease dominated the diagnosis of thyroid disease (30.43%). Significant association was found in weight changes with patients’ thyroid status; reduction in weight in first trimester and increment in weight in second trimester were mainly seen in the hyperthyroid group (p<0.01, p=0.027). Conclusion: The acceptable prevalence of 3.14% for thyroid disorders in pregnancy could be contributed by the iodine availability in this community. High prevalence of Graves’ disease warrants future screening for maternal thyroid stimulating immunoglobulin amongst hyperthyroid women.
format	Article
author	mohd Azemi, Nurul Azyati Zainal Abidin, Nur Afirah Mohd Amin, Adlina Nadhirah Daraup, Salmi Zakaria, Miza Hiryanti Shahar, Mohammad Arif
author_facet	mohd Azemi, Nurul Azyati Zainal Abidin, Nur Afirah Mohd Amin, Adlina Nadhirah Daraup, Salmi Zakaria, Miza Hiryanti Shahar, Mohammad Arif
author_sort	mohd Azemi, Nurul Azyati
title	Prevalence of thyroid disorders in pregnant women in Hospital Tengku Ampuan Afzan & International Islamic University Malaysia Medical Centre
title_short	Prevalence of thyroid disorders in pregnant women in Hospital Tengku Ampuan Afzan & International Islamic University Malaysia Medical Centre
title_full	Prevalence of thyroid disorders in pregnant women in Hospital Tengku Ampuan Afzan & International Islamic University Malaysia Medical Centre
title_fullStr	Prevalence of thyroid disorders in pregnant women in Hospital Tengku Ampuan Afzan & International Islamic University Malaysia Medical Centre
title_full_unstemmed	Prevalence of thyroid disorders in pregnant women in Hospital Tengku Ampuan Afzan & International Islamic University Malaysia Medical Centre
title_sort	prevalence of thyroid disorders in pregnant women in hospital tengku ampuan afzan & international islamic university malaysia medical centre
publisher	Kulliyyah of Medicine, International Islamic University Malaysia
publishDate	2018
url	http://irep.iium.edu.my/68716/ http://irep.iium.edu.my/68716/ http://irep.iium.edu.my/68716/1/Prevalence%20of%20thyroid%20disorders%20in%20pregnancy.pdf
first_indexed	2023-09-18T21:37:29Z
last_indexed	2023-09-18T21:37:29Z
_version_	1777412918204170240

Prevalence of thyroid disorders in pregnant women in Hospital Tengku Ampuan Afzan & International Islamic University Malaysia Medical Centre

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