Comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study

INTRODUCTION: There is no consensus on the optimal timing of liver resection in patients with synchronous colorectal liver metastasis. METHODS: Patients undergoing hepatic resections between 2004- 2013 for synchronous colorectal liver metastases were analyzed from a prospectively maintained and...

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Main Authors:	Elagili, Faisal, Ozuner, Gokhan, Berber, Eren, Akyuz, Muhammet, Cem Dural, Ahmet
Format:	Article
Language:	English
Published:	Elsevier 2014
Subjects:	RD Surgery
Online Access:	http://irep.iium.edu.my/69804/ http://irep.iium.edu.my/69804/ http://irep.iium.edu.my/69804/ http://irep.iium.edu.my/69804/2/liver%20resection.pdf

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spelling	iium-698042019-04-11T03:26:57Z http://irep.iium.edu.my/69804/ Comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study Elagili, Faisal Ozuner, Gokhan Berber, Eren Akyuz, Muhammet Cem Dural, Ahmet RD Surgery INTRODUCTION: There is no consensus on the optimal timing of liver resection in patients with synchronous colorectal liver metastasis. METHODS: Patients undergoing hepatic resections between 2004- 2013 for synchronous colorectal liver metastases were analyzed from a prospectively maintained and institutional review board approved database. Patients who underwent simultaneous resection of a colorectal primary and hepatic metastasis in a single operation (Group I) were case-matched 1:1with patients who underwent staged operation (Group II) according to age, sex, ASA classification, size of liver lesion and number of liver lesion. RESULTS: 66 patients (33 Group I, 33 Group II) were matched from a total cohort of 106 patients with synchronous colorectal liver metastasis. The patients’ characteristics of both groups were similar. 62% were male and the mean age was 55.511 years. Blood loss and duration of surgery did not differ between simultaneous resections and staged resection (p¼0.63; p¼0.14, respectively). Perioperative complication rate were similar in both groups (P¼0.70). There was no mortality. The median number of in-hospital days during the course of treatment was 9 (4-23) days in Group I and 6 (3-17) days in Group II (p <0.001). There was no difference in 2 years disease free survival and overall survival were found between Group I and Group II ( 30% and 34%, p¼ 0.58; 67% and 62%, p¼0.86 respectively). CONCLUSIONS: Simultaneous liver resections result in similar short and long eterm outcomes as in patients undergoing sequential resections for synchronous colorectal cancer with comparable metastatic disease burden. Elsevier 2014-10 Article PeerReviewed application/pdf en http://irep.iium.edu.my/69804/2/liver%20resection.pdf Elagili, Faisal and Ozuner, Gokhan and Berber, Eren and Akyuz, Muhammet and Cem Dural, Ahmet (2014) Comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study. Journal of The American College of Surgeons, 219 (4 Supplement). e75-e76. ISSN 1072-7515 https://www.journalacs.org/article/S1072-7515(14)01120-X/pdf 10.1016/j.jamcollsurg.2014.07.584
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RD Surgery
spellingShingle	RD Surgery Elagili, Faisal Ozuner, Gokhan Berber, Eren Akyuz, Muhammet Cem Dural, Ahmet Comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study
description	INTRODUCTION: There is no consensus on the optimal timing of liver resection in patients with synchronous colorectal liver metastasis. METHODS: Patients undergoing hepatic resections between 2004- 2013 for synchronous colorectal liver metastases were analyzed from a prospectively maintained and institutional review board approved database. Patients who underwent simultaneous resection of a colorectal primary and hepatic metastasis in a single operation (Group I) were case-matched 1:1with patients who underwent staged operation (Group II) according to age, sex, ASA classification, size of liver lesion and number of liver lesion. RESULTS: 66 patients (33 Group I, 33 Group II) were matched from a total cohort of 106 patients with synchronous colorectal liver metastasis. The patients’ characteristics of both groups were similar. 62% were male and the mean age was 55.511 years. Blood loss and duration of surgery did not differ between simultaneous resections and staged resection (p¼0.63; p¼0.14, respectively). Perioperative complication rate were similar in both groups (P¼0.70). There was no mortality. The median number of in-hospital days during the course of treatment was 9 (4-23) days in Group I and 6 (3-17) days in Group II (p <0.001). There was no difference in 2 years disease free survival and overall survival were found between Group I and Group II ( 30% and 34%, p¼ 0.58; 67% and 62%, p¼0.86 respectively). CONCLUSIONS: Simultaneous liver resections result in similar short and long eterm outcomes as in patients undergoing sequential resections for synchronous colorectal cancer with comparable metastatic disease burden.
format	Article
author	Elagili, Faisal Ozuner, Gokhan Berber, Eren Akyuz, Muhammet Cem Dural, Ahmet
author_facet	Elagili, Faisal Ozuner, Gokhan Berber, Eren Akyuz, Muhammet Cem Dural, Ahmet
author_sort	Elagili, Faisal
title	Comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study
title_short	Comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study
title_full	Comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study
title_fullStr	Comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study
title_full_unstemmed	Comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study
title_sort	comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study
publisher	Elsevier
publishDate	2014
url	http://irep.iium.edu.my/69804/ http://irep.iium.edu.my/69804/ http://irep.iium.edu.my/69804/ http://irep.iium.edu.my/69804/2/liver%20resection.pdf
first_indexed	2023-09-18T21:39:06Z
last_indexed	2023-09-18T21:39:06Z
_version_	1777413019513389056

Comparing simultaneous versus staged resection in patients with synchronous colorectal liver metastases: case match study

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