Successful intravenous thrombolysis of a wake-up stroke with underlying valvular atrial fibrillation

A 42-year-old female admitted with new-onset atrial fibrillation had a wake-up stroke on the high-dependency unit and the time last seen well (TLSW) was 6.5 h. She suffered left-sided body weakness and her National Institutes of Health Stroke Scale (NIHSS) score was 17. An emergency CT perfusion sho...

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Main Authors:	Koya Kutty, Shahedah, Ching, Soong Khoo, Wan Yahya, Wan Nur Nafisah, Ng, Chen Fei, Md Sari, Noor Ashikin, Mohd Yaakob, Mohd Naim, Osman, Syazarina Sharis, Zakaria, Rozman, Wan Zaidi, Wan Asyraf
Format:	Article
Language:	English English English
Published:	Royal College of Physicians of Edinburgh 2018
Subjects:	RF Otorhinolaryngology
Online Access:	http://irep.iium.edu.my/70141/ http://irep.iium.edu.my/70141/ http://irep.iium.edu.my/70141/ http://irep.iium.edu.my/70141/1/70141_Successful%20intravenous%20thrombolysis.pdf http://irep.iium.edu.my/70141/2/70141_Successful%20intravenous%20thrombolysis_SCOPUS.pdf http://irep.iium.edu.my/70141/3/70141_Successful%20intravenous%20thrombolysis_WOS.pdf

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recordtype	eprints
spelling	iium-701412019-01-25T06:02:15Z http://irep.iium.edu.my/70141/ Successful intravenous thrombolysis of a wake-up stroke with underlying valvular atrial fibrillation Koya Kutty, Shahedah Ching, Soong Khoo Wan Yahya, Wan Nur Nafisah Ng, Chen Fei Md Sari, Noor Ashikin Mohd Yaakob, Mohd Naim Osman, Syazarina Sharis Zakaria, Rozman Wan Zaidi, Wan Asyraf RF Otorhinolaryngology A 42-year-old female admitted with new-onset atrial fibrillation had a wake-up stroke on the high-dependency unit and the time last seen well (TLSW) was 6.5 h. She suffered left-sided body weakness and her National Institutes of Health Stroke Scale (NIHSS) score was 17. An emergency CT perfusion showed right M1 segment occlusion with more than 50% penumbra. She was given recombinant tissue plasminogen activator (r-tPA) at 9 h from TLSW. An immediate diagnostic angiogram with intention to treat, owing to the presence of large vessel occlusion, showed complete reperfusion after intravenous r-tPA. She was discharged with NIHSS of 2, and at 3-month follow up her Modified Rankin Scale was 0. We demonstrated a successful reperfusion and excellent clinical recovery with intravenous thrombolysis in a patient who presented with a wake-up stroke with underlying valvular atrial fibrillation despite evidence of large vessel occlusion. © 2018, Royal College of Physicians of Edinburgh. All rights reserved. Royal College of Physicians of Edinburgh 2018 Article PeerReviewed application/pdf en http://irep.iium.edu.my/70141/1/70141_Successful%20intravenous%20thrombolysis.pdf application/pdf en http://irep.iium.edu.my/70141/2/70141_Successful%20intravenous%20thrombolysis_SCOPUS.pdf application/pdf en http://irep.iium.edu.my/70141/3/70141_Successful%20intravenous%20thrombolysis_WOS.pdf Koya Kutty, Shahedah and Ching, Soong Khoo and Wan Yahya, Wan Nur Nafisah and Ng, Chen Fei and Md Sari, Noor Ashikin and Mohd Yaakob, Mohd Naim and Osman, Syazarina Sharis and Zakaria, Rozman and Wan Zaidi, Wan Asyraf (2018) Successful intravenous thrombolysis of a wake-up stroke with underlying valvular atrial fibrillation. Journal of the Royal College of Physicians of Edinburgh, 48 (3). pp. 239-241. ISSN 1478-2715 E-ISSN 2042-8189 https://www.rcpe.ac.uk/sites/default/files/jrcpe_48_3_shahedah.pdf 10.4997/JRCPE.2018.308
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	RF Otorhinolaryngology
spellingShingle	RF Otorhinolaryngology Koya Kutty, Shahedah Ching, Soong Khoo Wan Yahya, Wan Nur Nafisah Ng, Chen Fei Md Sari, Noor Ashikin Mohd Yaakob, Mohd Naim Osman, Syazarina Sharis Zakaria, Rozman Wan Zaidi, Wan Asyraf Successful intravenous thrombolysis of a wake-up stroke with underlying valvular atrial fibrillation
description	A 42-year-old female admitted with new-onset atrial fibrillation had a wake-up stroke on the high-dependency unit and the time last seen well (TLSW) was 6.5 h. She suffered left-sided body weakness and her National Institutes of Health Stroke Scale (NIHSS) score was 17. An emergency CT perfusion showed right M1 segment occlusion with more than 50% penumbra. She was given recombinant tissue plasminogen activator (r-tPA) at 9 h from TLSW. An immediate diagnostic angiogram with intention to treat, owing to the presence of large vessel occlusion, showed complete reperfusion after intravenous r-tPA. She was discharged with NIHSS of 2, and at 3-month follow up her Modified Rankin Scale was 0. We demonstrated a successful reperfusion and excellent clinical recovery with intravenous thrombolysis in a patient who presented with a wake-up stroke with underlying valvular atrial fibrillation despite evidence of large vessel occlusion. © 2018, Royal College of Physicians of Edinburgh. All rights reserved.
format	Article
author	Koya Kutty, Shahedah Ching, Soong Khoo Wan Yahya, Wan Nur Nafisah Ng, Chen Fei Md Sari, Noor Ashikin Mohd Yaakob, Mohd Naim Osman, Syazarina Sharis Zakaria, Rozman Wan Zaidi, Wan Asyraf
author_facet	Koya Kutty, Shahedah Ching, Soong Khoo Wan Yahya, Wan Nur Nafisah Ng, Chen Fei Md Sari, Noor Ashikin Mohd Yaakob, Mohd Naim Osman, Syazarina Sharis Zakaria, Rozman Wan Zaidi, Wan Asyraf
author_sort	Koya Kutty, Shahedah
title	Successful intravenous thrombolysis of a wake-up stroke with underlying valvular atrial fibrillation
title_short	Successful intravenous thrombolysis of a wake-up stroke with underlying valvular atrial fibrillation
title_full	Successful intravenous thrombolysis of a wake-up stroke with underlying valvular atrial fibrillation
title_fullStr	Successful intravenous thrombolysis of a wake-up stroke with underlying valvular atrial fibrillation
title_full_unstemmed	Successful intravenous thrombolysis of a wake-up stroke with underlying valvular atrial fibrillation
title_sort	successful intravenous thrombolysis of a wake-up stroke with underlying valvular atrial fibrillation
publisher	Royal College of Physicians of Edinburgh
publishDate	2018
url	http://irep.iium.edu.my/70141/ http://irep.iium.edu.my/70141/ http://irep.iium.edu.my/70141/ http://irep.iium.edu.my/70141/1/70141_Successful%20intravenous%20thrombolysis.pdf http://irep.iium.edu.my/70141/2/70141_Successful%20intravenous%20thrombolysis_SCOPUS.pdf http://irep.iium.edu.my/70141/3/70141_Successful%20intravenous%20thrombolysis_WOS.pdf
first_indexed	2023-09-18T21:39:34Z
last_indexed	2023-09-18T21:39:34Z
_version_	1777413049477496832

Successful intravenous thrombolysis of a wake-up stroke with underlying valvular atrial fibrillation

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