Screening of suitable ionic liquids as green solvents for extraction of eicosapentaenoic acid (EPA) from microalgae biomass using COSMO-RS model
Omega-3 poly unsaturated fatty acids (PUFA) particularly eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), have many health benefits including reducing the risk of cancer and cardiovascular disease. Recently, the use of ionic liquids (ILs) in lipid extraction from microalgae provides t...
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| Format: | Article |
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Multidisciplinary Digital Publishing Institute (MDPI)
2019
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| Online Access: | http://irep.iium.edu.my/70777/ http://irep.iium.edu.my/70777/ http://irep.iium.edu.my/70777/ http://irep.iium.edu.my/70777/19/70777_%20Screening%20of%20suitable%20ionic%20liquids%20as%20green%20solvents.pdf http://irep.iium.edu.my/70777/7/70777_Screening%20of%20Suitable%20Ionic%20Liquids_wos.pdf http://irep.iium.edu.my/70777/8/70777_Screening%20of%20Suitable%20Ionic%20Liquids_scopus.pdf |
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iium-70777 |
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eprints |
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iium-707772020-01-23T08:27:45Z http://irep.iium.edu.my/70777/ Screening of suitable ionic liquids as green solvents for extraction of eicosapentaenoic acid (EPA) from microalgae biomass using COSMO-RS model Motlagh, Shiva Rezaei Harun, Razif Awang Biak, Dayang Radiah Hussain, Siti Aslina Wan Ab Karim Ghani, Wan Azlina Khezri, Ramin Wilfred, Cecilia Devi Elgharbawy, Amal A.M. TP248.13 Biotechnology TX341 Nutrition. Foods and food supply Omega-3 poly unsaturated fatty acids (PUFA) particularly eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), have many health benefits including reducing the risk of cancer and cardiovascular disease. Recently, the use of ionic liquids (ILs) in lipid extraction from microalgae provides the potential to overcome common drawbacks, offers several other benefits. To date, very limited researches are available to focus on extracting microalgae lipid and PUFA in particular by using ILs. The objective of current work is to screen the potential ILs that can be applied in EPA extraction. In this study, fast ILs screening was performed with the help of a conductor like screening model for real solvents (COSMO-RS) and the ILs with higher capacity values for use in extraction of EPA were compared. According to the results, the highest capacity for EPA extraction among 352 screened cation/anion combinations belongs to [TMAm][SO4]. It is expected to achieve a higher yield of EPA once applying this combination as the solvent in the process of extraction. ILs with small anions were observed to have higher capacities, as well possessing higher charge density compared to larger ones, and therefore, they are more preferable for extraction purposes. Moreover, shorter alkyl chain cations are preferred when using imidazolium-based IL, which agrees with experimental data. Multidisciplinary Digital Publishing Institute (MDPI) 2019-02-16 Article PeerReviewed application/pdf en http://irep.iium.edu.my/70777/19/70777_%20Screening%20of%20suitable%20ionic%20liquids%20as%20green%20solvents.pdf application/pdf en http://irep.iium.edu.my/70777/7/70777_Screening%20of%20Suitable%20Ionic%20Liquids_wos.pdf application/pdf en http://irep.iium.edu.my/70777/8/70777_Screening%20of%20Suitable%20Ionic%20Liquids_scopus.pdf Motlagh, Shiva Rezaei and Harun, Razif and Awang Biak, Dayang Radiah and Hussain, Siti Aslina and Wan Ab Karim Ghani, Wan Azlina and Khezri, Ramin and Wilfred, Cecilia Devi and Elgharbawy, Amal A.M. (2019) Screening of suitable ionic liquids as green solvents for extraction of eicosapentaenoic acid (EPA) from microalgae biomass using COSMO-RS model. Molecules, 24 (4). pp. 1-18. ISSN 1420-3049 https://www.mdpi.com/1420-3049/24/4/713/htm 10.3390/molecules24040713 |
| repository_type |
Digital Repository |
| institution_category |
Local University |
| institution |
International Islamic University Malaysia |
| building |
IIUM Repository |
| collection |
Online Access |
| language |
English English English |
| topic |
TP248.13 Biotechnology TX341 Nutrition. Foods and food supply |
| spellingShingle |
TP248.13 Biotechnology TX341 Nutrition. Foods and food supply Motlagh, Shiva Rezaei Harun, Razif Awang Biak, Dayang Radiah Hussain, Siti Aslina Wan Ab Karim Ghani, Wan Azlina Khezri, Ramin Wilfred, Cecilia Devi Elgharbawy, Amal A.M. Screening of suitable ionic liquids as green solvents for extraction of eicosapentaenoic acid (EPA) from microalgae biomass using COSMO-RS model |
| description |
Omega-3 poly unsaturated fatty acids (PUFA) particularly eicosapentaenoic acid (EPA),
and docosahexaenoic acid (DHA), have many health benefits including reducing the risk of cancer
and cardiovascular disease. Recently, the use of ionic liquids (ILs) in lipid extraction from microalgae
provides the potential to overcome common drawbacks, offers several other benefits. To date, very
limited researches are available to focus on extracting microalgae lipid and PUFA in particular by
using ILs. The objective of current work is to screen the potential ILs that can be applied in EPA
extraction. In this study, fast ILs screening was performed with the help of a conductor like screening
model for real solvents (COSMO-RS) and the ILs with higher capacity values for use in extraction
of EPA were compared. According to the results, the highest capacity for EPA extraction among
352 screened cation/anion combinations belongs to [TMAm][SO4]. It is expected to achieve a higher
yield of EPA once applying this combination as the solvent in the process of extraction. ILs with small
anions were observed to have higher capacities, as well possessing higher charge density compared to
larger ones, and therefore, they are more preferable for extraction purposes. Moreover, shorter alkyl
chain cations are preferred when using imidazolium-based IL, which agrees with experimental data. |
| format |
Article |
| author |
Motlagh, Shiva Rezaei Harun, Razif Awang Biak, Dayang Radiah Hussain, Siti Aslina Wan Ab Karim Ghani, Wan Azlina Khezri, Ramin Wilfred, Cecilia Devi Elgharbawy, Amal A.M. |
| author_facet |
Motlagh, Shiva Rezaei Harun, Razif Awang Biak, Dayang Radiah Hussain, Siti Aslina Wan Ab Karim Ghani, Wan Azlina Khezri, Ramin Wilfred, Cecilia Devi Elgharbawy, Amal A.M. |
| author_sort |
Motlagh, Shiva Rezaei |
| title |
Screening of suitable ionic liquids as green solvents for extraction of eicosapentaenoic acid (EPA) from microalgae biomass using COSMO-RS model |
| title_short |
Screening of suitable ionic liquids as green solvents for extraction of eicosapentaenoic acid (EPA) from microalgae biomass using COSMO-RS model |
| title_full |
Screening of suitable ionic liquids as green solvents for extraction of eicosapentaenoic acid (EPA) from microalgae biomass using COSMO-RS model |
| title_fullStr |
Screening of suitable ionic liquids as green solvents for extraction of eicosapentaenoic acid (EPA) from microalgae biomass using COSMO-RS model |
| title_full_unstemmed |
Screening of suitable ionic liquids as green solvents for extraction of eicosapentaenoic acid (EPA) from microalgae biomass using COSMO-RS model |
| title_sort |
screening of suitable ionic liquids as green solvents for extraction of eicosapentaenoic acid (epa) from microalgae biomass using cosmo-rs model |
| publisher |
Multidisciplinary Digital Publishing Institute (MDPI) |
| publishDate |
2019 |
| url |
http://irep.iium.edu.my/70777/ http://irep.iium.edu.my/70777/ http://irep.iium.edu.my/70777/ http://irep.iium.edu.my/70777/19/70777_%20Screening%20of%20suitable%20ionic%20liquids%20as%20green%20solvents.pdf http://irep.iium.edu.my/70777/7/70777_Screening%20of%20Suitable%20Ionic%20Liquids_wos.pdf http://irep.iium.edu.my/70777/8/70777_Screening%20of%20Suitable%20Ionic%20Liquids_scopus.pdf |
| first_indexed |
2023-09-18T21:40:28Z |
| last_indexed |
2023-09-18T21:40:28Z |
| _version_ |
1777413105350868992 |