The effect of flaxseed extract on skin elasticity of the healing wound in rabbits

Introduction: Management of disturbed wounds, large skin defects and the areas where skin tension precludes wound closure is of high clinical importance. Healing in wounds occurs through epithelization and contraction processes (second-intentions healing) that may result in certain undesirable com...

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Main Authors:	Abdul Jabbar, Omar, Kashmola, Muhanad Ali Hamdon, Mustafa Al-Ahmad, Basma Ezzat, Mokhtar@Makhtar, Khairani Idah, Muhammad, Naznin, Abdul Rahim, Roslina, La, Qouta
Format:	Article
Language:	English English English
Published:	Kulliyyah of Medicine, International Islamic University Malaysia 2019
Subjects:	R Medicine (General) RB Pathology RL Dermatology
Online Access:	http://irep.iium.edu.my/71466/ http://irep.iium.edu.my/71466/ http://irep.iium.edu.my/71466/1/71466_The%20Effect%20of%20Flaxseed%20Extract%20on%20Skin.pdf http://irep.iium.edu.my/71466/7/71466_The%20effect%20of%20flaxseed%20extract%20on%20skin%20elasticity%20_scopus.pdf http://irep.iium.edu.my/71466/13/71466_The%20Effect%20of%20Flaxseed%20Extract%20on%20Skin%20Elasticity%20of%20The%20Healing%20Wound%20In%20Rabbits_wos.pdf

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recordtype	eprints
spelling	iium-714662020-02-06T00:14:40Z http://irep.iium.edu.my/71466/ The effect of flaxseed extract on skin elasticity of the healing wound in rabbits Abdul Jabbar, Omar Kashmola, Muhanad Ali Hamdon Mustafa Al-Ahmad, Basma Ezzat Mokhtar@Makhtar, Khairani Idah Muhammad, Naznin Abdul Rahim, Roslina La, Qouta R Medicine (General) RB Pathology RL Dermatology Introduction: Management of disturbed wounds, large skin defects and the areas where skin tension precludes wound closure is of high clinical importance. Healing in wounds occurs through epithelization and contraction processes (second-intentions healing) that may result in certain undesirable complications including keloid and formation of a fragile epithelial layer. Materials and methods: 27 white New Zealand rabbit included in this study divided into 3 groups; one group of 9 rabbits received Flaxseed gel topically for three time intervals (1, 7, and 14 days); a second group received Fucidin cream as positive control, while a third group has not received any treatment as negative control, Skin elasticity measurements were performed using the DermaLab system. Results: Throughout the study, skin elasticity was significantly greater in Flaxseed group than in others. Flaxseed decrease elasticity value from (3.46 ± 2.05). Hence, Young's modulus of skin elasticity in flaxseed group was (2.46 ± 1.02) after 14 days (p = 0.003), while no significant differences were evident in both Fucidin group (1.16 ± 0.77) and non-treated group (1.86 ± 1.40) (p = 0.019), accordingly flaxseed extract more reproducible than other groups demonstrating comparable efficacy in skin elasticity and distensibility. Conclusions: This study showed the therapeutic effect of flaxseed on biologic tissue. Elasticity evaluation demonstrated increased density and firmness in the network of collagen fibers in the dermis and subcutis during wound healing process promise in generating therapeutic gel to be used in wound healing process. Kulliyyah of Medicine, International Islamic University Malaysia 2019-04-01 Article PeerReviewed application/pdf en http://irep.iium.edu.my/71466/1/71466_The%20Effect%20of%20Flaxseed%20Extract%20on%20Skin.pdf application/pdf en http://irep.iium.edu.my/71466/7/71466_The%20effect%20of%20flaxseed%20extract%20on%20skin%20elasticity%20_scopus.pdf application/pdf en http://irep.iium.edu.my/71466/13/71466_The%20Effect%20of%20Flaxseed%20Extract%20on%20Skin%20Elasticity%20of%20The%20Healing%20Wound%20In%20Rabbits_wos.pdf Abdul Jabbar, Omar and Kashmola, Muhanad Ali Hamdon and Mustafa Al-Ahmad, Basma Ezzat and Mokhtar@Makhtar, Khairani Idah and Muhammad, Naznin and Abdul Rahim, Roslina and La, Qouta (2019) The effect of flaxseed extract on skin elasticity of the healing wound in rabbits. The International Medical Journal Malaysia, 18 (1). pp. 5-12. E-ISSN 1823-4631 http://iiumedic.net/imjm/v1/download/volume_18_no_1/Pages-from-IMJMVol18No1-005-012.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	R Medicine (General) RB Pathology RL Dermatology
spellingShingle	R Medicine (General) RB Pathology RL Dermatology Abdul Jabbar, Omar Kashmola, Muhanad Ali Hamdon Mustafa Al-Ahmad, Basma Ezzat Mokhtar@Makhtar, Khairani Idah Muhammad, Naznin Abdul Rahim, Roslina La, Qouta The effect of flaxseed extract on skin elasticity of the healing wound in rabbits
description	Introduction: Management of disturbed wounds, large skin defects and the areas where skin tension precludes wound closure is of high clinical importance. Healing in wounds occurs through epithelization and contraction processes (second-intentions healing) that may result in certain undesirable complications including keloid and formation of a fragile epithelial layer. Materials and methods: 27 white New Zealand rabbit included in this study divided into 3 groups; one group of 9 rabbits received Flaxseed gel topically for three time intervals (1, 7, and 14 days); a second group received Fucidin cream as positive control, while a third group has not received any treatment as negative control, Skin elasticity measurements were performed using the DermaLab system. Results: Throughout the study, skin elasticity was significantly greater in Flaxseed group than in others. Flaxseed decrease elasticity value from (3.46 ± 2.05). Hence, Young's modulus of skin elasticity in flaxseed group was (2.46 ± 1.02) after 14 days (p = 0.003), while no significant differences were evident in both Fucidin group (1.16 ± 0.77) and non-treated group (1.86 ± 1.40) (p = 0.019), accordingly flaxseed extract more reproducible than other groups demonstrating comparable efficacy in skin elasticity and distensibility. Conclusions: This study showed the therapeutic effect of flaxseed on biologic tissue. Elasticity evaluation demonstrated increased density and firmness in the network of collagen fibers in the dermis and subcutis during wound healing process promise in generating therapeutic gel to be used in wound healing process.
format	Article
author	Abdul Jabbar, Omar Kashmola, Muhanad Ali Hamdon Mustafa Al-Ahmad, Basma Ezzat Mokhtar@Makhtar, Khairani Idah Muhammad, Naznin Abdul Rahim, Roslina La, Qouta
author_facet	Abdul Jabbar, Omar Kashmola, Muhanad Ali Hamdon Mustafa Al-Ahmad, Basma Ezzat Mokhtar@Makhtar, Khairani Idah Muhammad, Naznin Abdul Rahim, Roslina La, Qouta
author_sort	Abdul Jabbar, Omar
title	The effect of flaxseed extract on skin elasticity of the healing wound in rabbits
title_short	The effect of flaxseed extract on skin elasticity of the healing wound in rabbits
title_full	The effect of flaxseed extract on skin elasticity of the healing wound in rabbits
title_fullStr	The effect of flaxseed extract on skin elasticity of the healing wound in rabbits
title_full_unstemmed	The effect of flaxseed extract on skin elasticity of the healing wound in rabbits
title_sort	effect of flaxseed extract on skin elasticity of the healing wound in rabbits
publisher	Kulliyyah of Medicine, International Islamic University Malaysia
publishDate	2019
url	http://irep.iium.edu.my/71466/ http://irep.iium.edu.my/71466/ http://irep.iium.edu.my/71466/1/71466_The%20Effect%20of%20Flaxseed%20Extract%20on%20Skin.pdf http://irep.iium.edu.my/71466/7/71466_The%20effect%20of%20flaxseed%20extract%20on%20skin%20elasticity%20_scopus.pdf http://irep.iium.edu.my/71466/13/71466_The%20Effect%20of%20Flaxseed%20Extract%20on%20Skin%20Elasticity%20of%20The%20Healing%20Wound%20In%20Rabbits_wos.pdf
first_indexed	2023-09-18T21:41:20Z
last_indexed	2023-09-18T21:41:20Z
_version_	1777413160223899648

The effect of flaxseed extract on skin elasticity of the healing wound in rabbits

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