Optimisation of squalene recovery from palm oil by-product using integrated ScCO2-pressure swing

Squalene is used as an ingredient in functional foods, pharmaceuticals, and cosmetics. Due to the limitation of squalene availability from predominant source which is shark liver oil and to sustain the environment by fully utilising the by-product of palm oil, an effort has been made to find a poten...

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Main Authors:	Suleiman, Norhidayah, Baharin, Badlishah Sham, Sarker, Md. Zaidul Islam, Mirhosseini, Seyed Hamed, Ali, Mohd Helmi
Format:	Article
Language:	English English
Published:	Malaysian Palm Oil Board 2018
Subjects:	TP248.13 Biotechnology
Online Access:	http://irep.iium.edu.my/72840/ http://irep.iium.edu.my/72840/ http://irep.iium.edu.my/72840/ http://irep.iium.edu.my/72840/1/72840%20Optimisation%20of%20squalene%20recovery%20from%20palm%20oil.pdf http://irep.iium.edu.my/72840/2/72840%20Optimisation%20of%20squalene%20recovery%20from%20palm%20oil%20SCOPUS.pdf

id	iium-72840
recordtype	eprints
spelling	iium-728402019-06-24T07:35:39Z http://irep.iium.edu.my/72840/ Optimisation of squalene recovery from palm oil by-product using integrated ScCO2-pressure swing Suleiman, Norhidayah Baharin, Badlishah Sham Sarker, Md. Zaidul Islam Mirhosseini, Seyed Hamed Ali, Mohd Helmi TP248.13 Biotechnology Squalene is used as an ingredient in functional foods, pharmaceuticals, and cosmetics. Due to the limitation of squalene availability from predominant source which is shark liver oil and to sustain the environment by fully utilising the by-product of palm oil, an effort has been made to find a potential source of squalene as an alternative to shark liver oil. The motivation for this work is to optimise its extraction from an alternative source, a palm oil by-product known as palm fatty acid distillate (PFAD), using supercritical carbon dioxide (sc-CO2) with the aid of a pressure swing technique. The measurements were performed using a sc-CO2 extraction in a fixed bed at temperatures of 40°C, 50°C, and 60°C, pressures of 20, 30 and 40 MPa, and holding times of 20, 30 and 40 min; high performance liquid chromatography (HPLC) was used for squalene content analysis, optimised with a central composite design using research surface methodology (RSM). The second-order polynomial mathematical model adequately fitted the experimental results. The maximum squalene content from the model was predicted to be 356.24 ppm under the set of conditions with pressure of 23 MPa, temperature at 40°C, and 20 min holding time. Malaysian Palm Oil Board 2018-12 Article PeerReviewed application/pdf en http://irep.iium.edu.my/72840/1/72840%20Optimisation%20of%20squalene%20recovery%20from%20palm%20oil.pdf application/pdf en http://irep.iium.edu.my/72840/2/72840%20Optimisation%20of%20squalene%20recovery%20from%20palm%20oil%20SCOPUS.pdf Suleiman, Norhidayah and Baharin, Badlishah Sham and Sarker, Md. Zaidul Islam and Mirhosseini, Seyed Hamed and Ali, Mohd Helmi (2018) Optimisation of squalene recovery from palm oil by-product using integrated ScCO2-pressure swing. Journal of Oil Palm Research, 30 (4). pp. 570-578. ISSN 1511-2780 http://jopr.mpob.gov.my/wp-content/uploads/2018/12/jopr2018v30dec-loh.pdf 10.21894/jopr.2018.0045
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	TP248.13 Biotechnology
spellingShingle	TP248.13 Biotechnology Suleiman, Norhidayah Baharin, Badlishah Sham Sarker, Md. Zaidul Islam Mirhosseini, Seyed Hamed Ali, Mohd Helmi Optimisation of squalene recovery from palm oil by-product using integrated ScCO2-pressure swing
description	Squalene is used as an ingredient in functional foods, pharmaceuticals, and cosmetics. Due to the limitation of squalene availability from predominant source which is shark liver oil and to sustain the environment by fully utilising the by-product of palm oil, an effort has been made to find a potential source of squalene as an alternative to shark liver oil. The motivation for this work is to optimise its extraction from an alternative source, a palm oil by-product known as palm fatty acid distillate (PFAD), using supercritical carbon dioxide (sc-CO2) with the aid of a pressure swing technique. The measurements were performed using a sc-CO2 extraction in a fixed bed at temperatures of 40°C, 50°C, and 60°C, pressures of 20, 30 and 40 MPa, and holding times of 20, 30 and 40 min; high performance liquid chromatography (HPLC) was used for squalene content analysis, optimised with a central composite design using research surface methodology (RSM). The second-order polynomial mathematical model adequately fitted the experimental results. The maximum squalene content from the model was predicted to be 356.24 ppm under the set of conditions with pressure of 23 MPa, temperature at 40°C, and 20 min holding time.
format	Article
author	Suleiman, Norhidayah Baharin, Badlishah Sham Sarker, Md. Zaidul Islam Mirhosseini, Seyed Hamed Ali, Mohd Helmi
author_facet	Suleiman, Norhidayah Baharin, Badlishah Sham Sarker, Md. Zaidul Islam Mirhosseini, Seyed Hamed Ali, Mohd Helmi
author_sort	Suleiman, Norhidayah
title	Optimisation of squalene recovery from palm oil by-product using integrated ScCO2-pressure swing
title_short	Optimisation of squalene recovery from palm oil by-product using integrated ScCO2-pressure swing
title_full	Optimisation of squalene recovery from palm oil by-product using integrated ScCO2-pressure swing
title_fullStr	Optimisation of squalene recovery from palm oil by-product using integrated ScCO2-pressure swing
title_full_unstemmed	Optimisation of squalene recovery from palm oil by-product using integrated ScCO2-pressure swing
title_sort	optimisation of squalene recovery from palm oil by-product using integrated scco2-pressure swing
publisher	Malaysian Palm Oil Board
publishDate	2018
url	http://irep.iium.edu.my/72840/ http://irep.iium.edu.my/72840/ http://irep.iium.edu.my/72840/ http://irep.iium.edu.my/72840/1/72840%20Optimisation%20of%20squalene%20recovery%20from%20palm%20oil.pdf http://irep.iium.edu.my/72840/2/72840%20Optimisation%20of%20squalene%20recovery%20from%20palm%20oil%20SCOPUS.pdf
first_indexed	2023-09-18T21:43:16Z
last_indexed	2023-09-18T21:43:16Z
_version_	1777413282073673728

Optimisation of squalene recovery from palm oil by-product using integrated ScCO2-pressure swing

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