Inflammatory response of bioscaffolds decellularized by sonication treatment

Decellularization of sonication system efficiency is dictated by evaluation of host immune response on scaffolds. This aim of this study is to examine the inflammatory response after implantation of bioscaffolds decellularized by sonication treatment at 35 days postsurgery in rats. In this study,...

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Main Authors: Hazwani, Aqilah, Sha'ban, Munirah, Azhim, Azran
Format: Conference or Workshop Item
Language:English
English
Published: Springer 2018
Subjects:
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http://irep.iium.edu.my/72879/
http://irep.iium.edu.my/72879/
http://irep.iium.edu.my/72879/14/72879%20Inflammatory%20Response.pdf
http://irep.iium.edu.my/72879/2/72879%20Inflammatory%20Response%20of%20Bioscaffolds%20Decellularized%20SCOPUS.pdf
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spelling iium-728792019-07-03T07:32:42Z http://irep.iium.edu.my/72879/ Inflammatory response of bioscaffolds decellularized by sonication treatment Hazwani, Aqilah Sha'ban, Munirah Azhim, Azran R Medicine (General) Decellularization of sonication system efficiency is dictated by evaluation of host immune response on scaffolds. This aim of this study is to examine the inflammatory response after implantation of bioscaffolds decellularized by sonication treatment at 35 days postsurgery in rats. In this study, aortic tissues decellularized by sonication treatment in 0.1 and 2% of Sodium Dodecyl Sulfate (SDS) detergents. Samples were washed for 5 days in Phosphate Buffer Saline (PBS) following decellularization. Samples were implanted in on the lower right thoracic cavity of rats for 35 days. To examine the inflammatory response, the implanted samples were explanted and evaluated histologically by Hematoxylin Eosin (H-E) staining. From the histological analysis, bioscaffolds decellularized by sonication treatment in response to macrophages shows the minimal inflammatory response. Minimal inflammatory response elicits by bioscaffolds suggests the safety of bioscaffolds prepared by sonication treatment as biomedical implants. Springer 2018 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/72879/14/72879%20Inflammatory%20Response.pdf application/pdf en http://irep.iium.edu.my/72879/2/72879%20Inflammatory%20Response%20of%20Bioscaffolds%20Decellularized%20SCOPUS.pdf Hazwani, Aqilah and Sha'ban, Munirah and Azhim, Azran (2018) Inflammatory response of bioscaffolds decellularized by sonication treatment. In: 2nd International Conference for Innovation in Biomedical Engineering and Life Sciences ICIBEL 2017 (in conjunction with APCMBE 2017), 10th–13th December 2017, Penang, Malaysia. https://link.springer.com/chapter/10.1007/978-981-10-7554-4_32 10.1007/978-981-10-7554-4_32
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
topic R Medicine (General)
spellingShingle R Medicine (General)
Hazwani, Aqilah
Sha'ban, Munirah
Azhim, Azran
Inflammatory response of bioscaffolds decellularized by sonication treatment
description Decellularization of sonication system efficiency is dictated by evaluation of host immune response on scaffolds. This aim of this study is to examine the inflammatory response after implantation of bioscaffolds decellularized by sonication treatment at 35 days postsurgery in rats. In this study, aortic tissues decellularized by sonication treatment in 0.1 and 2% of Sodium Dodecyl Sulfate (SDS) detergents. Samples were washed for 5 days in Phosphate Buffer Saline (PBS) following decellularization. Samples were implanted in on the lower right thoracic cavity of rats for 35 days. To examine the inflammatory response, the implanted samples were explanted and evaluated histologically by Hematoxylin Eosin (H-E) staining. From the histological analysis, bioscaffolds decellularized by sonication treatment in response to macrophages shows the minimal inflammatory response. Minimal inflammatory response elicits by bioscaffolds suggests the safety of bioscaffolds prepared by sonication treatment as biomedical implants.
format Conference or Workshop Item
author Hazwani, Aqilah
Sha'ban, Munirah
Azhim, Azran
author_facet Hazwani, Aqilah
Sha'ban, Munirah
Azhim, Azran
author_sort Hazwani, Aqilah
title Inflammatory response of bioscaffolds decellularized by sonication treatment
title_short Inflammatory response of bioscaffolds decellularized by sonication treatment
title_full Inflammatory response of bioscaffolds decellularized by sonication treatment
title_fullStr Inflammatory response of bioscaffolds decellularized by sonication treatment
title_full_unstemmed Inflammatory response of bioscaffolds decellularized by sonication treatment
title_sort inflammatory response of bioscaffolds decellularized by sonication treatment
publisher Springer
publishDate 2018
url http://irep.iium.edu.my/72879/
http://irep.iium.edu.my/72879/
http://irep.iium.edu.my/72879/
http://irep.iium.edu.my/72879/14/72879%20Inflammatory%20Response.pdf
http://irep.iium.edu.my/72879/2/72879%20Inflammatory%20Response%20of%20Bioscaffolds%20Decellularized%20SCOPUS.pdf
first_indexed 2023-09-18T21:43:20Z
last_indexed 2023-09-18T21:43:20Z
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