The changing incidence of dengue fever in Hulu Langat, Selangor: a 5-year registry-based analysis
INTRODUCTION: Dengue fever, a mosquito-borne disease that occurs in tropical and subtropical areas of the world, is a significant threat for the mankind in both developing and developed countries. Dengue virus infection is a systemic disease and has dynamic change in clinical phase. This resear...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Malaysian Medical Association
2019
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/73574/ http://irep.iium.edu.my/73574/ http://irep.iium.edu.my/73574/1/73574%20The%20changing%20incidence%20of%20dengue%20fever%20in%20Hulu%20Langat%2C%20Selangor.pdf |
| Summary: | INTRODUCTION: Dengue fever, a mosquito-borne
disease that occurs in tropical and subtropical areas of the
world, is a significant threat for the mankind in both
developing and developed countries. Dengue virus
infection is a systemic disease and has dynamic change in
clinical phase. This research aimed to study the
epidemiology of dengue with reference to demographic
profile, circulating serotypes and complications.
METHODS: A literature survey was conducted and
demographic data between 2014 and 2018 in e-Dengue
registry were analysed to describe the epidemiology of
dengue cases in Hulu Langat. RESULTS: The highest
incidence rate, 254.3 per 100,000 populations was
recorded in 2015 (n=14,939). Urban sub-districts (88.3%),
male (57%), Malay (61.5%), age group 18-40 years old
(51%) and landed house (61%) contributed most of the
cases. Case-fatality rate increased from 2014 to 2017
(0.0018 to 0.0022) but decreased in 2018 (0.0014). Out of
114 mortalities, majority were male (53%), age 18-40
years old (46%) and Malay (63%). Complications
recorded were liver failure (60%), renal failure (51%),
encephalitis (18%) and myocarditis (18%). In year 2014-
2015, DEN-1 serotype was dominantly reported (52.2%
and 56.5%), shifted to DEN-3 in year 2016-2017 (34.8%
and 43.4%) and DEN-2 in year 2018 (49.5%).
DISCUSSION: Hulu Langat, being hyperendemic, the
occurrence of multiple organ involvement following
dengue infections has become a frequent finding. The
study emphasizes the need of epidemiological and
entomological surveillance to monitor trends in dengue
distribution, seasonal patterns and circulating serotypes to
guide dengue control activities, especially in rapidly
growing urban and suburban areas. |
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