Slc6a4 and Htr2a gene Polymorphisms in Malay-Malaysian Schizophrenia

Slc6a4 and Htr2a gene Polymorphisms in Malay-Malaysian Schizophrenia

Schizophrenia (Sz) affect about 21 million people worldwide. This disorder alters perception, thoughts, affect and behaviour. Serotonin (5-Hydroxytryptamine, 5-HT) is a monoamine neurotransmitter which has been hypothesized to be abnormal in schizophrenia. The solute carrier family 6 member 4...

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Main Authors: A.Talib, Norlelawati, Abdullah, Nor Zamzila, Aladzemi, Farah Wahida
Format: Book
Language:English
Published: IIUM Press, International Islamic University Malaysia 2017
Subjects:
R Medicine (General)
RC Internal medicine
Online Access:http://irep.iium.edu.my/73663/
http://irep.iium.edu.my/73663/1/73663_slc6a4%20and%20htr2a%20gene%20polymorphisms%20in%20malay-malaysian%20schizophrenia.pdf
id iium-73663
recordtype eprints
spelling iium-736632019-10-17T01:50:08Z http://irep.iium.edu.my/73663/ Slc6a4 and Htr2a gene Polymorphisms in Malay-Malaysian Schizophrenia A.Talib, Norlelawati Abdullah, Nor Zamzila Aladzemi, Farah Wahida R Medicine (General) RC Internal medicine Schizophrenia (Sz) affect about 21 million people worldwide. This disorder alters perception, thoughts, affect and behaviour. Serotonin (5-Hydroxytryptamine, 5-HT) is a monoamine neurotransmitter which has been hypothesized to be abnormal in schizophrenia. The solute carrier family 6 member 4 (SLC6A4) gene and serotonin receptor 2A (HTR2A) gene are among the important genes within the serotonergic system-related genes family. The SLC6A4 gene encode for serotonin transporter (SERT) which regulates the synaptic concentration of serotonin by transporting serotonin molecules back to the pre-synaptic neuron while the HTR2A gene is another gene that encode for the serotonin receptor subtype 2A. Studies done previously failed to produce consistent result for specific locus of schizohrenia susceptibility IIUM Press, International Islamic University Malaysia 2017 Book PeerReviewed application/pdf en http://irep.iium.edu.my/73663/1/73663_slc6a4%20and%20htr2a%20gene%20polymorphisms%20in%20malay-malaysian%20schizophrenia.pdf A.Talib, Norlelawati and Abdullah, Nor Zamzila and Aladzemi, Farah Wahida (2017) Slc6a4 and Htr2a gene Polymorphisms in Malay-Malaysian Schizophrenia. IIUM Press, International Islamic University Malaysia, Kuala Lumpur, Malaysia. ISBN 978-967-418-724-8
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic R Medicine (General)
RC Internal medicine
spellingShingle R Medicine (General)
RC Internal medicine
A.Talib, Norlelawati
Abdullah, Nor Zamzila
Aladzemi, Farah Wahida
Slc6a4 and Htr2a gene Polymorphisms in Malay-Malaysian Schizophrenia
description Schizophrenia (Sz) affect about 21 million people worldwide. This disorder alters perception, thoughts, affect and behaviour. Serotonin (5-Hydroxytryptamine, 5-HT) is a monoamine neurotransmitter which has been hypothesized to be abnormal in schizophrenia. The solute carrier family 6 member 4 (SLC6A4) gene and serotonin receptor 2A (HTR2A) gene are among the important genes within the serotonergic system-related genes family. The SLC6A4 gene encode for serotonin transporter (SERT) which regulates the synaptic concentration of serotonin by transporting serotonin molecules back to the pre-synaptic neuron while the HTR2A gene is another gene that encode for the serotonin receptor subtype 2A. Studies done previously failed to produce consistent result for specific locus of schizohrenia susceptibility
format Book
author A.Talib, Norlelawati
Abdullah, Nor Zamzila
Aladzemi, Farah Wahida
author_facet A.Talib, Norlelawati
Abdullah, Nor Zamzila
Aladzemi, Farah Wahida
author_sort A.Talib, Norlelawati
title Slc6a4 and Htr2a gene Polymorphisms in Malay-Malaysian Schizophrenia
title_short Slc6a4 and Htr2a gene Polymorphisms in Malay-Malaysian Schizophrenia
title_full Slc6a4 and Htr2a gene Polymorphisms in Malay-Malaysian Schizophrenia
title_fullStr Slc6a4 and Htr2a gene Polymorphisms in Malay-Malaysian Schizophrenia
title_full_unstemmed Slc6a4 and Htr2a gene Polymorphisms in Malay-Malaysian Schizophrenia
title_sort slc6a4 and htr2a gene polymorphisms in malay-malaysian schizophrenia
publisher IIUM Press, International Islamic University Malaysia
publishDate 2017
url http://irep.iium.edu.my/73663/
http://irep.iium.edu.my/73663/1/73663_slc6a4%20and%20htr2a%20gene%20polymorphisms%20in%20malay-malaysian%20schizophrenia.pdf
first_indexed 2023-09-18T21:44:26Z
last_indexed 2023-09-18T21:44:26Z
_version_ 1777413354784030720

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