Antimacrobial Properties of gynura procumbens (Sambung Nyawa) leaves In methanolic and acidic extracts
Introduction: Gynura procumbens, commonly known as ‘sambung nyawa’ in Malaysia has been used traditionally as remedies for anti-inflammatory, anti-hyperlipidimic and anti-hyperglycemic. The purpose of the present study was to qualitatively evaluate the antimicrobial effects of Gynura procumbens e...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
KULLIYYAH OF ALLIED HEALTH SCIENCES, IIUM
2019
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/73954/ http://irep.iium.edu.my/73954/ http://irep.iium.edu.my/73954/1/179-Article%20Text-1123-2-10-20190809_daun%20sambung%20nyawa.pdf |
| Summary: | Introduction: Gynura procumbens, commonly known as ‘sambung nyawa’ in Malaysia has been used
traditionally as remedies for anti-inflammatory, anti-hyperlipidimic and anti-hyperglycemic. The
purpose of the present study was to qualitatively evaluate the antimicrobial effects of Gynura procumbens
extracts. Methods: The sample was extracted using methanol and acid hydrolysis. The antimicrobial
effects of the sample were determined by disc diffusion method against two bacteria and two fungi
namely E. coli, S. aureus, C. albicans and S. cerevisiae. Results: The results showed that the acidic extract of
G. procumbens has positive reactions towards E. coli, S. aureus and C. albicans with the presence of zone of
inhibition at the concentration of 150 mg/mL. Following the positive reaction, the minimum inhibitory
concentration (MIC) of the acidic extract was then evaluated by broth dilution method. The MIC of E. coli
and S. aureus were determined at concentration 37.5 mg/mL and 75 mg/mL for C. albicans. It indicated
that acidic extracts at lower concentration could inhibit the bacteria, but high concentration of extracts
was required in the inhibition of the fungi. Conclusion: It can be concluded that, the present study proves
that there is potential of antimicrobial effects in Gynura procumbens leaves extracts. |
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