Antimacrobial Properties of gynura procumbens (Sambung Nyawa) leaves In methanolic and acidic extracts

Introduction: Gynura procumbens, commonly known as ‘sambung nyawa’ in Malaysia has been used traditionally as remedies for anti-inflammatory, anti-hyperlipidimic and anti-hyperglycemic. The purpose of the present study was to qualitatively evaluate the antimicrobial effects of Gynura procumbens e...

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Main Authors: Haron, Normah, Mat Jusoh, Hanapi
Format: Article
Language:English
Published: KULLIYYAH OF ALLIED HEALTH SCIENCES, IIUM 2019
Subjects:
Online Access:http://irep.iium.edu.my/73954/
http://irep.iium.edu.my/73954/
http://irep.iium.edu.my/73954/1/179-Article%20Text-1123-2-10-20190809_daun%20sambung%20nyawa.pdf
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spelling iium-739542019-08-22T02:35:31Z http://irep.iium.edu.my/73954/ Antimacrobial Properties of gynura procumbens (Sambung Nyawa) leaves In methanolic and acidic extracts Haron, Normah Mat Jusoh, Hanapi RV Botanic, Thomsonian, and eclectic medicine RZ Other systems of medicine Introduction: Gynura procumbens, commonly known as ‘sambung nyawa’ in Malaysia has been used traditionally as remedies for anti-inflammatory, anti-hyperlipidimic and anti-hyperglycemic. The purpose of the present study was to qualitatively evaluate the antimicrobial effects of Gynura procumbens extracts. Methods: The sample was extracted using methanol and acid hydrolysis. The antimicrobial effects of the sample were determined by disc diffusion method against two bacteria and two fungi namely E. coli, S. aureus, C. albicans and S. cerevisiae. Results: The results showed that the acidic extract of G. procumbens has positive reactions towards E. coli, S. aureus and C. albicans with the presence of zone of inhibition at the concentration of 150 mg/mL. Following the positive reaction, the minimum inhibitory concentration (MIC) of the acidic extract was then evaluated by broth dilution method. The MIC of E. coli and S. aureus were determined at concentration 37.5 mg/mL and 75 mg/mL for C. albicans. It indicated that acidic extracts at lower concentration could inhibit the bacteria, but high concentration of extracts was required in the inhibition of the fungi. Conclusion: It can be concluded that, the present study proves that there is potential of antimicrobial effects in Gynura procumbens leaves extracts. KULLIYYAH OF ALLIED HEALTH SCIENCES, IIUM 2019-08-05 Article PeerReviewed application/pdf en http://irep.iium.edu.my/73954/1/179-Article%20Text-1123-2-10-20190809_daun%20sambung%20nyawa.pdf Haron, Normah and Mat Jusoh, Hanapi (2019) Antimacrobial Properties of gynura procumbens (Sambung Nyawa) leaves In methanolic and acidic extracts. INTERNATIONAL JOURNAL OF ALLIED HEALTH SCIENCES, 3 (2). pp. 605-615. https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/179
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic RV Botanic, Thomsonian, and eclectic medicine
RZ Other systems of medicine
spellingShingle RV Botanic, Thomsonian, and eclectic medicine
RZ Other systems of medicine
Haron, Normah
Mat Jusoh, Hanapi
Antimacrobial Properties of gynura procumbens (Sambung Nyawa) leaves In methanolic and acidic extracts
description Introduction: Gynura procumbens, commonly known as ‘sambung nyawa’ in Malaysia has been used traditionally as remedies for anti-inflammatory, anti-hyperlipidimic and anti-hyperglycemic. The purpose of the present study was to qualitatively evaluate the antimicrobial effects of Gynura procumbens extracts. Methods: The sample was extracted using methanol and acid hydrolysis. The antimicrobial effects of the sample were determined by disc diffusion method against two bacteria and two fungi namely E. coli, S. aureus, C. albicans and S. cerevisiae. Results: The results showed that the acidic extract of G. procumbens has positive reactions towards E. coli, S. aureus and C. albicans with the presence of zone of inhibition at the concentration of 150 mg/mL. Following the positive reaction, the minimum inhibitory concentration (MIC) of the acidic extract was then evaluated by broth dilution method. The MIC of E. coli and S. aureus were determined at concentration 37.5 mg/mL and 75 mg/mL for C. albicans. It indicated that acidic extracts at lower concentration could inhibit the bacteria, but high concentration of extracts was required in the inhibition of the fungi. Conclusion: It can be concluded that, the present study proves that there is potential of antimicrobial effects in Gynura procumbens leaves extracts.
format Article
author Haron, Normah
Mat Jusoh, Hanapi
author_facet Haron, Normah
Mat Jusoh, Hanapi
author_sort Haron, Normah
title Antimacrobial Properties of gynura procumbens (Sambung Nyawa) leaves In methanolic and acidic extracts
title_short Antimacrobial Properties of gynura procumbens (Sambung Nyawa) leaves In methanolic and acidic extracts
title_full Antimacrobial Properties of gynura procumbens (Sambung Nyawa) leaves In methanolic and acidic extracts
title_fullStr Antimacrobial Properties of gynura procumbens (Sambung Nyawa) leaves In methanolic and acidic extracts
title_full_unstemmed Antimacrobial Properties of gynura procumbens (Sambung Nyawa) leaves In methanolic and acidic extracts
title_sort antimacrobial properties of gynura procumbens (sambung nyawa) leaves in methanolic and acidic extracts
publisher KULLIYYAH OF ALLIED HEALTH SCIENCES, IIUM
publishDate 2019
url http://irep.iium.edu.my/73954/
http://irep.iium.edu.my/73954/
http://irep.iium.edu.my/73954/1/179-Article%20Text-1123-2-10-20190809_daun%20sambung%20nyawa.pdf
first_indexed 2023-09-18T21:44:51Z
last_indexed 2023-09-18T21:44:51Z
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