Antimacrobial Properties of gynura procumbens (Sambung Nyawa) leaves In methanolic and acidic extracts
Introduction: Gynura procumbens, commonly known as ‘sambung nyawa’ in Malaysia has been used traditionally as remedies for anti-inflammatory, anti-hyperlipidimic and anti-hyperglycemic. The purpose of the present study was to qualitatively evaluate the antimicrobial effects of Gynura procumbens e...
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KULLIYYAH OF ALLIED HEALTH SCIENCES, IIUM
2019
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iium-739542019-08-22T02:35:31Z http://irep.iium.edu.my/73954/ Antimacrobial Properties of gynura procumbens (Sambung Nyawa) leaves In methanolic and acidic extracts Haron, Normah Mat Jusoh, Hanapi RV Botanic, Thomsonian, and eclectic medicine RZ Other systems of medicine Introduction: Gynura procumbens, commonly known as ‘sambung nyawa’ in Malaysia has been used traditionally as remedies for anti-inflammatory, anti-hyperlipidimic and anti-hyperglycemic. The purpose of the present study was to qualitatively evaluate the antimicrobial effects of Gynura procumbens extracts. Methods: The sample was extracted using methanol and acid hydrolysis. The antimicrobial effects of the sample were determined by disc diffusion method against two bacteria and two fungi namely E. coli, S. aureus, C. albicans and S. cerevisiae. Results: The results showed that the acidic extract of G. procumbens has positive reactions towards E. coli, S. aureus and C. albicans with the presence of zone of inhibition at the concentration of 150 mg/mL. Following the positive reaction, the minimum inhibitory concentration (MIC) of the acidic extract was then evaluated by broth dilution method. The MIC of E. coli and S. aureus were determined at concentration 37.5 mg/mL and 75 mg/mL for C. albicans. It indicated that acidic extracts at lower concentration could inhibit the bacteria, but high concentration of extracts was required in the inhibition of the fungi. Conclusion: It can be concluded that, the present study proves that there is potential of antimicrobial effects in Gynura procumbens leaves extracts. KULLIYYAH OF ALLIED HEALTH SCIENCES, IIUM 2019-08-05 Article PeerReviewed application/pdf en http://irep.iium.edu.my/73954/1/179-Article%20Text-1123-2-10-20190809_daun%20sambung%20nyawa.pdf Haron, Normah and Mat Jusoh, Hanapi (2019) Antimacrobial Properties of gynura procumbens (Sambung Nyawa) leaves In methanolic and acidic extracts. INTERNATIONAL JOURNAL OF ALLIED HEALTH SCIENCES, 3 (2). pp. 605-615. https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/179 |
| repository_type |
Digital Repository |
| institution_category |
Local University |
| institution |
International Islamic University Malaysia |
| building |
IIUM Repository |
| collection |
Online Access |
| language |
English |
| topic |
RV Botanic, Thomsonian, and eclectic medicine RZ Other systems of medicine |
| spellingShingle |
RV Botanic, Thomsonian, and eclectic medicine RZ Other systems of medicine Haron, Normah Mat Jusoh, Hanapi Antimacrobial Properties of gynura procumbens (Sambung Nyawa) leaves In methanolic and acidic extracts |
| description |
Introduction: Gynura procumbens, commonly known as ‘sambung nyawa’ in Malaysia has been used
traditionally as remedies for anti-inflammatory, anti-hyperlipidimic and anti-hyperglycemic. The
purpose of the present study was to qualitatively evaluate the antimicrobial effects of Gynura procumbens
extracts. Methods: The sample was extracted using methanol and acid hydrolysis. The antimicrobial
effects of the sample were determined by disc diffusion method against two bacteria and two fungi
namely E. coli, S. aureus, C. albicans and S. cerevisiae. Results: The results showed that the acidic extract of
G. procumbens has positive reactions towards E. coli, S. aureus and C. albicans with the presence of zone of
inhibition at the concentration of 150 mg/mL. Following the positive reaction, the minimum inhibitory
concentration (MIC) of the acidic extract was then evaluated by broth dilution method. The MIC of E. coli
and S. aureus were determined at concentration 37.5 mg/mL and 75 mg/mL for C. albicans. It indicated
that acidic extracts at lower concentration could inhibit the bacteria, but high concentration of extracts
was required in the inhibition of the fungi. Conclusion: It can be concluded that, the present study proves
that there is potential of antimicrobial effects in Gynura procumbens leaves extracts. |
| format |
Article |
| author |
Haron, Normah Mat Jusoh, Hanapi |
| author_facet |
Haron, Normah Mat Jusoh, Hanapi |
| author_sort |
Haron, Normah |
| title |
Antimacrobial Properties of gynura procumbens (Sambung Nyawa) leaves In methanolic and acidic extracts |
| title_short |
Antimacrobial Properties of gynura procumbens (Sambung Nyawa) leaves In methanolic and acidic extracts |
| title_full |
Antimacrobial Properties of gynura procumbens (Sambung Nyawa) leaves In methanolic and acidic extracts |
| title_fullStr |
Antimacrobial Properties of gynura procumbens (Sambung Nyawa) leaves In methanolic and acidic extracts |
| title_full_unstemmed |
Antimacrobial Properties of gynura procumbens (Sambung Nyawa) leaves In methanolic and acidic extracts |
| title_sort |
antimacrobial properties of gynura procumbens (sambung nyawa) leaves in methanolic and acidic extracts |
| publisher |
KULLIYYAH OF ALLIED HEALTH SCIENCES, IIUM |
| publishDate |
2019 |
| url |
http://irep.iium.edu.my/73954/ http://irep.iium.edu.my/73954/ http://irep.iium.edu.my/73954/1/179-Article%20Text-1123-2-10-20190809_daun%20sambung%20nyawa.pdf |
| first_indexed |
2023-09-18T21:44:51Z |
| last_indexed |
2023-09-18T21:44:51Z |
| _version_ |
1777413380970119168 |