Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) – masquerade diagnosis: a case report

Diagnostic challenge is seen in Systemic Lupus Erythematosus (SLE) due to insidious onset, unpredictable course and broad spectrum of clinical presentation [1]. SLE can mimic other diseases manifestation and possibility not fulfilling the classification criteria at the earlier course of the disease...

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Main Authors: Mohd Hanafi, Mohd Sharil Iman, Che Man, Mohammad, Che Alhadi, Shahidah
Format: Article
Language:English
Published: Science Forecast Publications 2019
Subjects:
Online Access:http://irep.iium.edu.my/74793/
http://irep.iium.edu.my/74793/
http://irep.iium.edu.my/74793/1/Dr.%20Mohd%20Aug%20NPSLE.pdf
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spelling iium-747932019-10-11T08:28:06Z http://irep.iium.edu.my/74793/ Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) – masquerade diagnosis: a case report Mohd Hanafi, Mohd Sharil Iman Che Man, Mohammad Che Alhadi, Shahidah R Medicine (General) RA Public aspects of medicine Diagnostic challenge is seen in Systemic Lupus Erythematosus (SLE) due to insidious onset, unpredictable course and broad spectrum of clinical presentation [1]. SLE can mimic other diseases manifestation and possibility not fulfilling the classification criteria at the earlier course of the disease [1]. We highlighted a case of a man, lived with diagnosis of Schizophrenia for almost 15 years subsequently revealed him suffered from neuropsychiatric lupus as he fulfilled the SLE classification criteria. His initial presentation was altered sensorium treated as acute psychosis- the tip of an iceberg to the underlying disease [2]. His multiple admissions to psychiatric ward were believed contributed by episode of lupus flare [2,3]. Necessary investigation is important to exclude another medical condition before make a diagnosis of Schizophrenia using DSM-V criteria [2]. The misdiagnosis has significantly impaired his social life and untreated disease had leads to morbidity and severe organ damage. This case emphasizes on the crucial aspect of assessing patient as a whole, follow-up the progression and re-evaluates patient’s condition for a new hint. Even though there is no cure yet for SLE, correct and early diagnosis is able to guide for individualized treatment and thus helping in good disease control that warrant better outcome [4]. Science Forecast Publications 2019-08-22 Article PeerReviewed application/pdf en http://irep.iium.edu.my/74793/1/Dr.%20Mohd%20Aug%20NPSLE.pdf Mohd Hanafi, Mohd Sharil Iman and Che Man, Mohammad and Che Alhadi, Shahidah (2019) Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) – masquerade diagnosis: a case report. Journal of Family Medicine Forecast, 2 (2). pp. 1-3. ISSN 2643-7864 https://scienceforecastoa.com/Articles/JFM-V2-E2-1021.pdf
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic R Medicine (General)
RA Public aspects of medicine
spellingShingle R Medicine (General)
RA Public aspects of medicine
Mohd Hanafi, Mohd Sharil Iman
Che Man, Mohammad
Che Alhadi, Shahidah
Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) – masquerade diagnosis: a case report
description Diagnostic challenge is seen in Systemic Lupus Erythematosus (SLE) due to insidious onset, unpredictable course and broad spectrum of clinical presentation [1]. SLE can mimic other diseases manifestation and possibility not fulfilling the classification criteria at the earlier course of the disease [1]. We highlighted a case of a man, lived with diagnosis of Schizophrenia for almost 15 years subsequently revealed him suffered from neuropsychiatric lupus as he fulfilled the SLE classification criteria. His initial presentation was altered sensorium treated as acute psychosis- the tip of an iceberg to the underlying disease [2]. His multiple admissions to psychiatric ward were believed contributed by episode of lupus flare [2,3]. Necessary investigation is important to exclude another medical condition before make a diagnosis of Schizophrenia using DSM-V criteria [2]. The misdiagnosis has significantly impaired his social life and untreated disease had leads to morbidity and severe organ damage. This case emphasizes on the crucial aspect of assessing patient as a whole, follow-up the progression and re-evaluates patient’s condition for a new hint. Even though there is no cure yet for SLE, correct and early diagnosis is able to guide for individualized treatment and thus helping in good disease control that warrant better outcome [4].
format Article
author Mohd Hanafi, Mohd Sharil Iman
Che Man, Mohammad
Che Alhadi, Shahidah
author_facet Mohd Hanafi, Mohd Sharil Iman
Che Man, Mohammad
Che Alhadi, Shahidah
author_sort Mohd Hanafi, Mohd Sharil Iman
title Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) – masquerade diagnosis: a case report
title_short Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) – masquerade diagnosis: a case report
title_full Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) – masquerade diagnosis: a case report
title_fullStr Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) – masquerade diagnosis: a case report
title_full_unstemmed Neuropsychiatric Systemic Lupus Erythematosus (NPSLE) – masquerade diagnosis: a case report
title_sort neuropsychiatric systemic lupus erythematosus (npsle) – masquerade diagnosis: a case report
publisher Science Forecast Publications
publishDate 2019
url http://irep.iium.edu.my/74793/
http://irep.iium.edu.my/74793/
http://irep.iium.edu.my/74793/1/Dr.%20Mohd%20Aug%20NPSLE.pdf
first_indexed 2023-09-18T21:45:51Z
last_indexed 2023-09-18T21:45:51Z
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