Cryptosporidium-host Interaction alters regulation of oncomiRNAs and tumor suppressor miRNA expression

Cryptosporidium-host Interaction alters regulation of oncomiRNAs and tumor suppressor miRNA expression

The apicomplexan parasite Cryptosporidium is well-known for its capability to induce cryptosporidiosis, a severe diarrheal disease in human and animals. Cryptosporidium can also be a potential pathogen in human for cancer progression, particularly colorectal cancer. This review was designed to outli...

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Main Authors: Başak, Feyza, Jainul, Mohammed Abdullah, Mat Yusof, Afzan
Format: Article
Language:English
Published: Asian Network for Scientific Information 2019
Subjects:
Q Science (General)
Online Access:http://irep.iium.edu.my/75063/
http://irep.iium.edu.my/75063/
http://irep.iium.edu.my/75063/
http://irep.iium.edu.my/75063/1/Ba%C5%9Fak%20et%20al.%2C%20%282019%29.pdf
id iium-75063
recordtype eprints
spelling iium-750632019-10-30T03:51:21Z http://irep.iium.edu.my/75063/ Cryptosporidium-host Interaction alters regulation of oncomiRNAs and tumor suppressor miRNA expression Başak, Feyza Jainul, Mohammed Abdullah Mat Yusof, Afzan Q Science (General) The apicomplexan parasite Cryptosporidium is well-known for its capability to induce cryptosporidiosis, a severe diarrheal disease in human and animals. Cryptosporidium can also be a potential pathogen in human for cancer progression, particularly colorectal cancer. This review was designed to outline the information about the life cycle of the Cryptosporidium, the consequences of Cryptosporidium infection into the response mechanism in immune compromised host and finally the regulation of oncomiRNAs and tumor suppressor miRNAs upon Cryptosporidium infection. Host-Cryptosporidium interaction caused alteration of expression of a series of microRNAs or miRNAs as a result of controlling defense mechanism. Regulation of miRNAs in the infected cells may be identified as possible biomarkers in cancer progression. Upregulation of oncomicroRNAs or oncomiRNAs and the downregulation of tumor suppressor miRNAs in the host epithelial cells due to the Cryptosporidium infection may lead to cancer initiation on human. Asian Network for Scientific Information 2019 Article PeerReviewed application/pdf en http://irep.iium.edu.my/75063/1/Ba%C5%9Fak%20et%20al.%2C%20%282019%29.pdf Başak, Feyza and Jainul, Mohammed Abdullah and Mat Yusof, Afzan (2019) Cryptosporidium-host Interaction alters regulation of oncomiRNAs and tumor suppressor miRNA expression. Journal of Biological Sciences, 19 (4). pp. 272-279. ISSN 1727-3048 E-ISSN 1812-5719 http://docsdrive.com/pdfs/ansinet/jbs/2019/272-279.pdf 10.3923/jbs.2019.272.279
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic Q Science (General)
spellingShingle Q Science (General)
Başak, Feyza
Jainul, Mohammed Abdullah
Mat Yusof, Afzan
Cryptosporidium-host Interaction alters regulation of oncomiRNAs and tumor suppressor miRNA expression
description The apicomplexan parasite Cryptosporidium is well-known for its capability to induce cryptosporidiosis, a severe diarrheal disease in human and animals. Cryptosporidium can also be a potential pathogen in human for cancer progression, particularly colorectal cancer. This review was designed to outline the information about the life cycle of the Cryptosporidium, the consequences of Cryptosporidium infection into the response mechanism in immune compromised host and finally the regulation of oncomiRNAs and tumor suppressor miRNAs upon Cryptosporidium infection. Host-Cryptosporidium interaction caused alteration of expression of a series of microRNAs or miRNAs as a result of controlling defense mechanism. Regulation of miRNAs in the infected cells may be identified as possible biomarkers in cancer progression. Upregulation of oncomicroRNAs or oncomiRNAs and the downregulation of tumor suppressor miRNAs in the host epithelial cells due to the Cryptosporidium infection may lead to cancer initiation on human.
format Article
author Başak, Feyza
Jainul, Mohammed Abdullah
Mat Yusof, Afzan
author_facet Başak, Feyza
Jainul, Mohammed Abdullah
Mat Yusof, Afzan
author_sort Başak, Feyza
title Cryptosporidium-host Interaction alters regulation of oncomiRNAs and tumor suppressor miRNA expression
title_short Cryptosporidium-host Interaction alters regulation of oncomiRNAs and tumor suppressor miRNA expression
title_full Cryptosporidium-host Interaction alters regulation of oncomiRNAs and tumor suppressor miRNA expression
title_fullStr Cryptosporidium-host Interaction alters regulation of oncomiRNAs and tumor suppressor miRNA expression
title_full_unstemmed Cryptosporidium-host Interaction alters regulation of oncomiRNAs and tumor suppressor miRNA expression
title_sort cryptosporidium-host interaction alters regulation of oncomirnas and tumor suppressor mirna expression
publisher Asian Network for Scientific Information
publishDate 2019
url http://irep.iium.edu.my/75063/
http://irep.iium.edu.my/75063/
http://irep.iium.edu.my/75063/
http://irep.iium.edu.my/75063/1/Ba%C5%9Fak%20et%20al.%2C%20%282019%29.pdf
first_indexed 2023-09-18T21:46:14Z
last_indexed 2023-09-18T21:46:14Z
_version_ 1777413468035481600

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