Effects of Eurycoma longifolia jack (Tongkat Ali) alcoholic root extract against oral pathogens

Introduction: Eurycoma longifolia jack (E.L) is a herbal medicinal plant of South-East Asian origin, popularly recognized as ‘Tongkat Ali.’ The plant roots have been scientifically proven to have many biological effects including antibacterial activity however, no previous research to date has st...

Full description

Bibliographic Details
Main Authors:	Alloha, Irani, Binti Aziz, Nurul ‘Ain Liyana, Faisal, Ghasak Ghazi, Abllah, Zurainie, Arzmi, Mohd Hafiz
Format:	Article
Language:	English English
Published:	2019
Subjects:	RB Pathology
Online Access:	http://irep.iium.edu.my/75384/ http://irep.iium.edu.my/75384/ http://irep.iium.edu.my/75384/ http://irep.iium.edu.my/75384/7/75384%20Effects%20of%20Eurycoma%20Longifolia%20Jack.pdf http://irep.iium.edu.my/75384/8/75384%20Effects%20of%20Eurycoma%20Longifolia%20Jack%20SCOPUS.pdf

id	iium-75384
recordtype	eprints
spelling	iium-753842019-11-15T01:47:14Z http://irep.iium.edu.my/75384/ Effects of Eurycoma longifolia jack (Tongkat Ali) alcoholic root extract against oral pathogens Alloha, Irani Binti Aziz, Nurul ‘Ain Liyana Faisal, Ghasak Ghazi Abllah, Zurainie Arzmi, Mohd Hafiz RB Pathology Introduction: Eurycoma longifolia jack (E.L) is a herbal medicinal plant of South-East Asian origin, popularly recognized as ‘Tongkat Ali.’ The plant roots have been scientifically proven to have many biological effects including antibacterial activity however, no previous research to date has studied the effect on oral pathogens including cariogenic bacteria. This study was done to determine the antibacterial and antifungal activities of E.L. root extract against three common oral pathogens. Material and Methods: The microorganisms used were Candida albicans, Streptococcus mutans and Lactobacillus casei. E.L root was extracted using soxhlet method. Disc diffusion assay was conducted using extract concentration of 200 mg/ml. Nystatin and Ampicillin were used as positive control for fungal and bacterial tests respectively. Minimum Inhibitory Concentration (MIC) was done to determine the lowest inhibitory concentration of the extract on the microorganisms. Results: E.L extract inhibited the growth of Candida albicans and Streptococcus mutans at a concentration of 200 mg/ ml with a zone of inhibition of 16.0 ± 3.0 mm and 7.0 ± 1.0 mm respectively. There was no antimicrobial effect of the extract on Lactobacillus casei. The MIC of E.L extract against both Candida albicans and Streptococcus mutans was 25 mg/ml. Conclusions: The results from this study revealed the potential use of Eurycoma longifolia jack as an antimicrobial agent which can be used to produce new oral care products. 2019-10 Article PeerReviewed application/pdf en http://irep.iium.edu.my/75384/7/75384%20Effects%20of%20Eurycoma%20Longifolia%20Jack.pdf application/pdf en http://irep.iium.edu.my/75384/8/75384%20Effects%20of%20Eurycoma%20Longifolia%20Jack%20SCOPUS.pdf Alloha, Irani and Binti Aziz, Nurul ‘Ain Liyana and Faisal, Ghasak Ghazi and Abllah, Zurainie and Arzmi, Mohd Hafiz (2019) Effects of Eurycoma longifolia jack (Tongkat Ali) alcoholic root extract against oral pathogens. Pharmacognosy Journal, 11 (5). pp. 1299-1302. ISSN 0975-3575 https://phcogj.com/sites/default/files/PJ-11-6-165.pdf 10.5530/pj.2019.11.201
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	RB Pathology
spellingShingle	RB Pathology Alloha, Irani Binti Aziz, Nurul ‘Ain Liyana Faisal, Ghasak Ghazi Abllah, Zurainie Arzmi, Mohd Hafiz Effects of Eurycoma longifolia jack (Tongkat Ali) alcoholic root extract against oral pathogens
description	Introduction: Eurycoma longifolia jack (E.L) is a herbal medicinal plant of South-East Asian origin, popularly recognized as ‘Tongkat Ali.’ The plant roots have been scientifically proven to have many biological effects including antibacterial activity however, no previous research to date has studied the effect on oral pathogens including cariogenic bacteria. This study was done to determine the antibacterial and antifungal activities of E.L. root extract against three common oral pathogens. Material and Methods: The microorganisms used were Candida albicans, Streptococcus mutans and Lactobacillus casei. E.L root was extracted using soxhlet method. Disc diffusion assay was conducted using extract concentration of 200 mg/ml. Nystatin and Ampicillin were used as positive control for fungal and bacterial tests respectively. Minimum Inhibitory Concentration (MIC) was done to determine the lowest inhibitory concentration of the extract on the microorganisms. Results: E.L extract inhibited the growth of Candida albicans and Streptococcus mutans at a concentration of 200 mg/ ml with a zone of inhibition of 16.0 ± 3.0 mm and 7.0 ± 1.0 mm respectively. There was no antimicrobial effect of the extract on Lactobacillus casei. The MIC of E.L extract against both Candida albicans and Streptococcus mutans was 25 mg/ml. Conclusions: The results from this study revealed the potential use of Eurycoma longifolia jack as an antimicrobial agent which can be used to produce new oral care products.
format	Article
author	Alloha, Irani Binti Aziz, Nurul ‘Ain Liyana Faisal, Ghasak Ghazi Abllah, Zurainie Arzmi, Mohd Hafiz
author_facet	Alloha, Irani Binti Aziz, Nurul ‘Ain Liyana Faisal, Ghasak Ghazi Abllah, Zurainie Arzmi, Mohd Hafiz
author_sort	Alloha, Irani
title	Effects of Eurycoma longifolia jack (Tongkat Ali) alcoholic root extract against oral pathogens
title_short	Effects of Eurycoma longifolia jack (Tongkat Ali) alcoholic root extract against oral pathogens
title_full	Effects of Eurycoma longifolia jack (Tongkat Ali) alcoholic root extract against oral pathogens
title_fullStr	Effects of Eurycoma longifolia jack (Tongkat Ali) alcoholic root extract against oral pathogens
title_full_unstemmed	Effects of Eurycoma longifolia jack (Tongkat Ali) alcoholic root extract against oral pathogens
title_sort	effects of eurycoma longifolia jack (tongkat ali) alcoholic root extract against oral pathogens
publishDate	2019
url	http://irep.iium.edu.my/75384/ http://irep.iium.edu.my/75384/ http://irep.iium.edu.my/75384/ http://irep.iium.edu.my/75384/7/75384%20Effects%20of%20Eurycoma%20Longifolia%20Jack.pdf http://irep.iium.edu.my/75384/8/75384%20Effects%20of%20Eurycoma%20Longifolia%20Jack%20SCOPUS.pdf
first_indexed	2023-09-18T21:46:39Z
last_indexed	2023-09-18T21:46:39Z
_version_	1777413494993321984

Effects of Eurycoma longifolia jack (Tongkat Ali) alcoholic root extract against oral pathogens

Similar Items