Prescribing of non-steroidal anti-inflammatory drugs, tramadol and opioids in children: patterns of its utilization

Background: Analgesic is commonly used in children but little is known about its patterns of utilization. This study explored the patterns of analgesic prescribing in children. Methods: This cross sectional study used prescription databases of tertiary hospital settings in Malaysia from 2010 to...

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Main Author: Zin, Che Suraya
Format: Conference or Workshop Item
Language:English
English
English
Published: 2019
Subjects:
Online Access:http://irep.iium.edu.my/75877/
http://irep.iium.edu.my/75877/1/191104_main%20page_program.pdf
http://irep.iium.edu.my/75877/2/191104_opioid_children%20pres_ten%20years%20opioid_naeem_poster_program.pdf
http://irep.iium.edu.my/75877/3/191009-Poster_icprp_children%20prescribing.pdf
id iium-75877
recordtype eprints
spelling iium-758772019-11-12T07:13:48Z http://irep.iium.edu.my/75877/ Prescribing of non-steroidal anti-inflammatory drugs, tramadol and opioids in children: patterns of its utilization Zin, Che Suraya RM Therapeutics. Pharmacology Background: Analgesic is commonly used in children but little is known about its patterns of utilization. This study explored the patterns of analgesic prescribing in children. Methods: This cross sectional study used prescription databases of tertiary hospital settings in Malaysia from 2010 to 2016. Prescriptions for nine NSAIDs (diclofenac, ketoprofen, etoricoxib, celecoxib, ibuprofen, indomethacin, mefenamic acid, meloxicam and naproxen), tramadol and five other opioids (morphine, oxycodone, fentanyl, buprenorphine and dihydrocodeine) prescribed for children age < 18 years old were included. Number of annual patients and prescriptions were measured and analysed using Stata v15. Results: During a 7-year study period, a total of 5040 analgesic prescriptions of the nine NSAIDs, tramadol, and five other opioids were prescribed for 2460 paediatric patients (81.8% NSAIDs patients, 17.9% tramadol patients, and 0.3% opioid patients). Ibuprofen was the primary analgesic in young children less than 12 years old (≤2 years old (y.o) (75%), 3-5 y.o (85%) and.6-12 y.o (56.3%)). While there was a wide range of analgesics used in older children (above 12 years old) with the majority for naproxen (13 to 15 y.o (28.2%) and 16 to 17 y.o (28.2%). Other frequently prescribed analgesics for older children included ibuprofen (20.6%) and diclofenac (18.2%)) for 12 to 15 y.o and diclofenac (26.7%) and tramadol (17.6%)) for 16-17 y.o. Conclusion: Ibuprofen was the primary analgesic for children less than 12 years old while there was a wide range of analgesics prescribed for children age above 12 years old including naproxen, diclofenac and tramadol. 2019-10-19 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/75877/1/191104_main%20page_program.pdf application/pdf en http://irep.iium.edu.my/75877/2/191104_opioid_children%20pres_ten%20years%20opioid_naeem_poster_program.pdf application/pdf en http://irep.iium.edu.my/75877/3/191009-Poster_icprp_children%20prescribing.pdf Zin, Che Suraya (2019) Prescribing of non-steroidal anti-inflammatory drugs, tramadol and opioids in children: patterns of its utilization. In: International Conference on Pharmaceutical Research and Pharmacy Practice cum 14th IIUM-MPS Pharmacy Scientific Conference (ICPRP 2019), 19-20th October 2019, Hotel Istana Kuala Lumpur. (Unpublished)
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
English
topic RM Therapeutics. Pharmacology
spellingShingle RM Therapeutics. Pharmacology
Zin, Che Suraya
Prescribing of non-steroidal anti-inflammatory drugs, tramadol and opioids in children: patterns of its utilization
description Background: Analgesic is commonly used in children but little is known about its patterns of utilization. This study explored the patterns of analgesic prescribing in children. Methods: This cross sectional study used prescription databases of tertiary hospital settings in Malaysia from 2010 to 2016. Prescriptions for nine NSAIDs (diclofenac, ketoprofen, etoricoxib, celecoxib, ibuprofen, indomethacin, mefenamic acid, meloxicam and naproxen), tramadol and five other opioids (morphine, oxycodone, fentanyl, buprenorphine and dihydrocodeine) prescribed for children age < 18 years old were included. Number of annual patients and prescriptions were measured and analysed using Stata v15. Results: During a 7-year study period, a total of 5040 analgesic prescriptions of the nine NSAIDs, tramadol, and five other opioids were prescribed for 2460 paediatric patients (81.8% NSAIDs patients, 17.9% tramadol patients, and 0.3% opioid patients). Ibuprofen was the primary analgesic in young children less than 12 years old (≤2 years old (y.o) (75%), 3-5 y.o (85%) and.6-12 y.o (56.3%)). While there was a wide range of analgesics used in older children (above 12 years old) with the majority for naproxen (13 to 15 y.o (28.2%) and 16 to 17 y.o (28.2%). Other frequently prescribed analgesics for older children included ibuprofen (20.6%) and diclofenac (18.2%)) for 12 to 15 y.o and diclofenac (26.7%) and tramadol (17.6%)) for 16-17 y.o. Conclusion: Ibuprofen was the primary analgesic for children less than 12 years old while there was a wide range of analgesics prescribed for children age above 12 years old including naproxen, diclofenac and tramadol.
format Conference or Workshop Item
author Zin, Che Suraya
author_facet Zin, Che Suraya
author_sort Zin, Che Suraya
title Prescribing of non-steroidal anti-inflammatory drugs, tramadol and opioids in children: patterns of its utilization
title_short Prescribing of non-steroidal anti-inflammatory drugs, tramadol and opioids in children: patterns of its utilization
title_full Prescribing of non-steroidal anti-inflammatory drugs, tramadol and opioids in children: patterns of its utilization
title_fullStr Prescribing of non-steroidal anti-inflammatory drugs, tramadol and opioids in children: patterns of its utilization
title_full_unstemmed Prescribing of non-steroidal anti-inflammatory drugs, tramadol and opioids in children: patterns of its utilization
title_sort prescribing of non-steroidal anti-inflammatory drugs, tramadol and opioids in children: patterns of its utilization
publishDate 2019
url http://irep.iium.edu.my/75877/
http://irep.iium.edu.my/75877/1/191104_main%20page_program.pdf
http://irep.iium.edu.my/75877/2/191104_opioid_children%20pres_ten%20years%20opioid_naeem_poster_program.pdf
http://irep.iium.edu.my/75877/3/191009-Poster_icprp_children%20prescribing.pdf
first_indexed 2023-09-18T21:47:19Z
last_indexed 2023-09-18T21:47:19Z
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