Clinical outcomes and quality of life of patients with short-term and long-term opioid therapy for the treatment of non- cancer pain

Introduction: Data from the US showed that there are increasing evidences of opioid-related harms such as opioid overdose deaths in long term opioid use for the treatment of chronic non-cancer pain. There is lack of data from Malaysia on opioid use particularly on its opioid related clinical outcom...

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Main Authors:	Abdullah Sani, Asween Rowena, Zin, Che Suraya
Format:	Conference or Workshop Item
Language:	English English English
Published:	2019
Subjects:	RM Therapeutics. Pharmacology
Online Access:	http://irep.iium.edu.my/76016/ http://irep.iium.edu.my/76016/1/191104_main%20page_program.pdf http://irep.iium.edu.my/76016/2/191104_asween_poster_program.pdf http://irep.iium.edu.my/76016/3/191105_ICPRP_poster_Asween.pdf

id	iium-76016
recordtype	eprints
spelling	iium-760162019-11-12T07:23:19Z http://irep.iium.edu.my/76016/ Clinical outcomes and quality of life of patients with short-term and long-term opioid therapy for the treatment of non- cancer pain Abdullah Sani, Asween Rowena Zin, Che Suraya RM Therapeutics. Pharmacology Introduction: Data from the US showed that there are increasing evidences of opioid-related harms such as opioid overdose deaths in long term opioid use for the treatment of chronic non-cancer pain. There is lack of data from Malaysia on opioid use particularly on its opioid related clinical outcomes. Objectives: To examine the clinical outcomes and quality of life of short-term and long-term opioid use in patients with non-cancer pain. Methods: This was a prospective clinical study where patients (age ≥18 years old) with non-cancer pain currently treated with opioids were recruited from three pain clinics in Malaysia. Patients were stratified into short-term or long-term opioid users based on opioid use ≥ 90 days. Outcome measures included pain intensity and pain interference with daily activities assessed by Brief Pain Inventory-Short Form, health-related quality of life assessed by Short-Form 36v2 and pain medication profiles assessed by Medication Quantification Scale-III (MQS-III. These measures were compared between short- and long-term opioid users. Results: Of the 61 non-cancer pain patients recruited, 49.2% (n=) were short-term and 50.8%(n=) were long-term opioid users. There were no statistically significant differences in the pain intensity, overall pain interference, health-related quality of life, and pain medication profiles between short-term and long-term opioid users in this study. Conclusion: Long-term opioid use did not significantly improve the clinical outcomes of patients with non-cancer pain which further supports the evidence of lack of benefits of opioids therapy in this condition. 2019-10-19 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/76016/1/191104_main%20page_program.pdf application/pdf en http://irep.iium.edu.my/76016/2/191104_asween_poster_program.pdf application/pdf en http://irep.iium.edu.my/76016/3/191105_ICPRP_poster_Asween.pdf Abdullah Sani, Asween Rowena and Zin, Che Suraya (2019) Clinical outcomes and quality of life of patients with short-term and long-term opioid therapy for the treatment of non- cancer pain. In: International Conference on Pharmaceutical Research and Pharmacy Practice cum 14th IIUM-MPS Pharmacy Scientific Conference (ICPRP 2019), 19-20th October 2019, Hotel Istana Kuala Lumpur. (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	RM Therapeutics. Pharmacology
spellingShingle	RM Therapeutics. Pharmacology Abdullah Sani, Asween Rowena Zin, Che Suraya Clinical outcomes and quality of life of patients with short-term and long-term opioid therapy for the treatment of non- cancer pain
description	Introduction: Data from the US showed that there are increasing evidences of opioid-related harms such as opioid overdose deaths in long term opioid use for the treatment of chronic non-cancer pain. There is lack of data from Malaysia on opioid use particularly on its opioid related clinical outcomes. Objectives: To examine the clinical outcomes and quality of life of short-term and long-term opioid use in patients with non-cancer pain. Methods: This was a prospective clinical study where patients (age ≥18 years old) with non-cancer pain currently treated with opioids were recruited from three pain clinics in Malaysia. Patients were stratified into short-term or long-term opioid users based on opioid use ≥ 90 days. Outcome measures included pain intensity and pain interference with daily activities assessed by Brief Pain Inventory-Short Form, health-related quality of life assessed by Short-Form 36v2 and pain medication profiles assessed by Medication Quantification Scale-III (MQS-III. These measures were compared between short- and long-term opioid users. Results: Of the 61 non-cancer pain patients recruited, 49.2% (n=) were short-term and 50.8%(n=) were long-term opioid users. There were no statistically significant differences in the pain intensity, overall pain interference, health-related quality of life, and pain medication profiles between short-term and long-term opioid users in this study. Conclusion: Long-term opioid use did not significantly improve the clinical outcomes of patients with non-cancer pain which further supports the evidence of lack of benefits of opioids therapy in this condition.
format	Conference or Workshop Item
author	Abdullah Sani, Asween Rowena Zin, Che Suraya
author_facet	Abdullah Sani, Asween Rowena Zin, Che Suraya
author_sort	Abdullah Sani, Asween Rowena
title	Clinical outcomes and quality of life of patients with short-term and long-term opioid therapy for the treatment of non- cancer pain
title_short	Clinical outcomes and quality of life of patients with short-term and long-term opioid therapy for the treatment of non- cancer pain
title_full	Clinical outcomes and quality of life of patients with short-term and long-term opioid therapy for the treatment of non- cancer pain
title_fullStr	Clinical outcomes and quality of life of patients with short-term and long-term opioid therapy for the treatment of non- cancer pain
title_full_unstemmed	Clinical outcomes and quality of life of patients with short-term and long-term opioid therapy for the treatment of non- cancer pain
title_sort	clinical outcomes and quality of life of patients with short-term and long-term opioid therapy for the treatment of non- cancer pain
publishDate	2019
url	http://irep.iium.edu.my/76016/ http://irep.iium.edu.my/76016/1/191104_main%20page_program.pdf http://irep.iium.edu.my/76016/2/191104_asween_poster_program.pdf http://irep.iium.edu.my/76016/3/191105_ICPRP_poster_Asween.pdf
first_indexed	2023-09-18T21:47:30Z
last_indexed	2023-09-18T21:47:30Z
_version_	1777413547856232448

Clinical outcomes and quality of life of patients with short-term and long-term opioid therapy for the treatment of non- cancer pain

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