Colon cancer in patients younger than age 50 in Kuantan: case series
Colorectal cancer (CRC) is the second most common cancer in Malaysia. In general, patients aged > 65 years comprise the majority of the population with CRC. However, recent reports indicate its increasing incidence in younger populations. We describe 4 cases of early onset colorectal cancer in...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Kulliyyah of Medicine, IIUM Kuantan
2019
|
| Subjects: | |
| Online Access: | http://irep.iium.edu.my/76871/ http://irep.iium.edu.my/76871/ http://irep.iium.edu.my/76871/1/76871_Colon%20cancer%20in%20patients%20younger%20than%20age%2050_new.pdf |
| Summary: | Colorectal cancer (CRC) is the second most common cancer in
Malaysia. In general, patients aged > 65 years comprise the majority of the
population with CRC. However, recent reports indicate its increasing incidence in
younger populations. We describe 4 cases of early onset colorectal cancer in
Kuantan. Materials and method: This is a descriptive study of a small series of
patients. Data between 2018 and 2019 were obtained from medical charts. Results:
We diagnosed four patients under the age of 50 with colon cancer (75% male), the
median age was 36 (23-47), with no comorbidities. None of the patient had family
history of colorectal cancer. The majority of our patients presented with
complication of tumour (2 perforation, 1 obstruction) required emergency surgeries.
Only one patient presented with rectal bleeding and was found to have tumor
of the rectosigmoid junction. Two patients had tumor at descending colon and one
at the splenic flexure. From this case series, we found there were one patient for
every stage of colorectal cancer. Carcinoembryonic (CEA) levels were elevated at
baseline in only two patients. Conclusion: Incidence of colon cancer rises among
young patients in Kuantan.Further studies are needed to clarify the clinical and
biological characteristics of colon cancer, improve its treatment strategies, and
promote better outcomes in young patients. |
|---|