Colon cancer in patients younger than age 50 in Kuantan: case series

Colorectal cancer (CRC) is the second most common cancer in Malaysia. In general, patients aged > 65 years comprise the majority of the population with CRC. However, recent reports indicate its increasing incidence in younger populations. We describe 4 cases of early onset colorectal cancer in...

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Main Authors: AK, Nurul Syazwani, K, Muhammad Afiq, Sainal, Yusof, Elagili, Faisal, Md Nor, Azmi
Format: Article
Language:English
Published: Kulliyyah of Medicine, IIUM Kuantan 2019
Subjects:
Online Access:http://irep.iium.edu.my/76871/
http://irep.iium.edu.my/76871/
http://irep.iium.edu.my/76871/1/76871_Colon%20cancer%20in%20patients%20younger%20than%20age%2050_new.pdf
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spelling iium-768712020-01-29T03:22:02Z http://irep.iium.edu.my/76871/ Colon cancer in patients younger than age 50 in Kuantan: case series AK, Nurul Syazwani K, Muhammad Afiq Sainal, Yusof Elagili, Faisal Md Nor, Azmi RD Surgery Colorectal cancer (CRC) is the second most common cancer in Malaysia. In general, patients aged > 65 years comprise the majority of the population with CRC. However, recent reports indicate its increasing incidence in younger populations. We describe 4 cases of early onset colorectal cancer in Kuantan. Materials and method: This is a descriptive study of a small series of patients. Data between 2018 and 2019 were obtained from medical charts. Results: We diagnosed four patients under the age of 50 with colon cancer (75% male), the median age was 36 (23-47), with no comorbidities. None of the patient had family history of colorectal cancer. The majority of our patients presented with complication of tumour (2 perforation, 1 obstruction) required emergency surgeries. Only one patient presented with rectal bleeding and was found to have tumor of the rectosigmoid junction. Two patients had tumor at descending colon and one at the splenic flexure. From this case series, we found there were one patient for every stage of colorectal cancer. Carcinoembryonic (CEA) levels were elevated at baseline in only two patients. Conclusion: Incidence of colon cancer rises among young patients in Kuantan.Further studies are needed to clarify the clinical and biological characteristics of colon cancer, improve its treatment strategies, and promote better outcomes in young patients. Kulliyyah of Medicine, IIUM Kuantan 2019 Article PeerReviewed application/pdf en http://irep.iium.edu.my/76871/1/76871_Colon%20cancer%20in%20patients%20younger%20than%20age%2050_new.pdf AK, Nurul Syazwani and K, Muhammad Afiq and Sainal, Yusof and Elagili, Faisal and Md Nor, Azmi (2019) Colon cancer in patients younger than age 50 in Kuantan: case series. International Medical Journal of Malaysia, 18 (Supplementary) (Issue 2). p. 55. ISSN 1823-4631. https://journals.iium.edu.my/kom/index.php/imjm/article/view/633/393
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic RD Surgery
spellingShingle RD Surgery
AK, Nurul Syazwani
K, Muhammad Afiq
Sainal, Yusof
Elagili, Faisal
Md Nor, Azmi
Colon cancer in patients younger than age 50 in Kuantan: case series
description Colorectal cancer (CRC) is the second most common cancer in Malaysia. In general, patients aged > 65 years comprise the majority of the population with CRC. However, recent reports indicate its increasing incidence in younger populations. We describe 4 cases of early onset colorectal cancer in Kuantan. Materials and method: This is a descriptive study of a small series of patients. Data between 2018 and 2019 were obtained from medical charts. Results: We diagnosed four patients under the age of 50 with colon cancer (75% male), the median age was 36 (23-47), with no comorbidities. None of the patient had family history of colorectal cancer. The majority of our patients presented with complication of tumour (2 perforation, 1 obstruction) required emergency surgeries. Only one patient presented with rectal bleeding and was found to have tumor of the rectosigmoid junction. Two patients had tumor at descending colon and one at the splenic flexure. From this case series, we found there were one patient for every stage of colorectal cancer. Carcinoembryonic (CEA) levels were elevated at baseline in only two patients. Conclusion: Incidence of colon cancer rises among young patients in Kuantan.Further studies are needed to clarify the clinical and biological characteristics of colon cancer, improve its treatment strategies, and promote better outcomes in young patients.
format Article
author AK, Nurul Syazwani
K, Muhammad Afiq
Sainal, Yusof
Elagili, Faisal
Md Nor, Azmi
author_facet AK, Nurul Syazwani
K, Muhammad Afiq
Sainal, Yusof
Elagili, Faisal
Md Nor, Azmi
author_sort AK, Nurul Syazwani
title Colon cancer in patients younger than age 50 in Kuantan: case series
title_short Colon cancer in patients younger than age 50 in Kuantan: case series
title_full Colon cancer in patients younger than age 50 in Kuantan: case series
title_fullStr Colon cancer in patients younger than age 50 in Kuantan: case series
title_full_unstemmed Colon cancer in patients younger than age 50 in Kuantan: case series
title_sort colon cancer in patients younger than age 50 in kuantan: case series
publisher Kulliyyah of Medicine, IIUM Kuantan
publishDate 2019
url http://irep.iium.edu.my/76871/
http://irep.iium.edu.my/76871/
http://irep.iium.edu.my/76871/1/76871_Colon%20cancer%20in%20patients%20younger%20than%20age%2050_new.pdf
first_indexed 2023-09-18T21:48:33Z
last_indexed 2023-09-18T21:48:33Z
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