Hydrodistillation and soxhlet extraction of agarwood leaf extract from Aquilaria malaccensis

Agarwood (A. malaccensis) is a valuable tree; highly sought after the resin and its essential oil. It also possesses bioactive compounds that are beneficial for health. However, less is focused on the agarwood leaf despite the recorded use in traditional medicine. As such, this present work focuse...

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Main Authors:	Hashim, Yumi Zuhanis Has-Yun, Mat Jamil, Mohamad Akmal, Jamal, Parveen, Zainurin, Nur Aimi Aliah, Syed Abdul Azzizz, Saripah Salbiah
Format:	Article
Language:	English English
Published:	Universiti Teknologi Malaysia ( UTM ) 2019
Subjects:	Q Science (General)
Online Access:	http://irep.iium.edu.my/77203/ http://irep.iium.edu.my/77203/ http://irep.iium.edu.my/77203/1/Paper_Hashim%20et%20al%202019%20%28MJFAS%29.pdf http://irep.iium.edu.my/77203/7/77203_Hydrodistillation%20and%20Soxhlet%20extraction_wos.pdf

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recordtype	eprints
spelling	iium-772032020-01-09T03:39:29Z http://irep.iium.edu.my/77203/ Hydrodistillation and soxhlet extraction of agarwood leaf extract from Aquilaria malaccensis Hashim, Yumi Zuhanis Has-Yun Mat Jamil, Mohamad Akmal Jamal, Parveen Zainurin, Nur Aimi Aliah Syed Abdul Azzizz, Saripah Salbiah Q Science (General) Agarwood (A. malaccensis) is a valuable tree; highly sought after the resin and its essential oil. It also possesses bioactive compounds that are beneficial for health. However, less is focused on the agarwood leaf despite the recorded use in traditional medicine. As such, this present work focused on the screening of operational parameters of hydrodistillation and Soxhlet extraction of agarwood leaf extract (ALEX) with subsequent phytochemical and gas chromatography mass spectrometry (GCMS) analyses. Hydrodistillation failed to obtain any essential oil. Therefore, only soxhlet extraction was further studied based on Plackett-Burman design generated using design expert software, version 6. The parameters studied were solvent type and volume, time, leaf type and particle size. Based on the ALEX yield obtained, solvent type was found to be the most significant parameters followed by solvent volume, particle size and time. Meanwhile leaf type was found to be the least influential parameter. Ethanol gave higher yield as compared to hexane. Run 2 gave the highest ALEX yield (121.34 ± 31.6 mg/g) and Run 4 gave the lowest yield (20.38 ± 4.1 mg/g). Based on phytochemical analysis, ALEX possess phenol, flavonoid, alkaloid, saponin and steroid compounds . GCMS analysis has identified a total of 50 compounds from ALEX in 12 experiments. Hexadecanoic acid was found to be the major compound in run 2 (highest yield) and phytol was found to be the major compound in run 4 (lowest yield). To this end, ALEX was succesfully obtained through Soxhlet extraction and the significant parameters can be further studied to achive optimal yield. Universiti Teknologi Malaysia ( UTM ) 2019 Article PeerReviewed application/pdf en http://irep.iium.edu.my/77203/1/Paper_Hashim%20et%20al%202019%20%28MJFAS%29.pdf application/pdf en http://irep.iium.edu.my/77203/7/77203_Hydrodistillation%20and%20Soxhlet%20extraction_wos.pdf Hashim, Yumi Zuhanis Has-Yun and Mat Jamil, Mohamad Akmal and Jamal, Parveen and Zainurin, Nur Aimi Aliah and Syed Abdul Azzizz, Saripah Salbiah (2019) Hydrodistillation and soxhlet extraction of agarwood leaf extract from Aquilaria malaccensis. Malaysian Journal of Fundamental and Applied Science, 15 (6). 842 -846. ISSN 2289-5981 E-ISSN 2289-599X. https://mjfas.utm.my/index.php/mjfas/article/view/1589/pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	Q Science (General)
spellingShingle	Q Science (General) Hashim, Yumi Zuhanis Has-Yun Mat Jamil, Mohamad Akmal Jamal, Parveen Zainurin, Nur Aimi Aliah Syed Abdul Azzizz, Saripah Salbiah Hydrodistillation and soxhlet extraction of agarwood leaf extract from Aquilaria malaccensis
description	Agarwood (A. malaccensis) is a valuable tree; highly sought after the resin and its essential oil. It also possesses bioactive compounds that are beneficial for health. However, less is focused on the agarwood leaf despite the recorded use in traditional medicine. As such, this present work focused on the screening of operational parameters of hydrodistillation and Soxhlet extraction of agarwood leaf extract (ALEX) with subsequent phytochemical and gas chromatography mass spectrometry (GCMS) analyses. Hydrodistillation failed to obtain any essential oil. Therefore, only soxhlet extraction was further studied based on Plackett-Burman design generated using design expert software, version 6. The parameters studied were solvent type and volume, time, leaf type and particle size. Based on the ALEX yield obtained, solvent type was found to be the most significant parameters followed by solvent volume, particle size and time. Meanwhile leaf type was found to be the least influential parameter. Ethanol gave higher yield as compared to hexane. Run 2 gave the highest ALEX yield (121.34 ± 31.6 mg/g) and Run 4 gave the lowest yield (20.38 ± 4.1 mg/g). Based on phytochemical analysis, ALEX possess phenol, flavonoid, alkaloid, saponin and steroid compounds . GCMS analysis has identified a total of 50 compounds from ALEX in 12 experiments. Hexadecanoic acid was found to be the major compound in run 2 (highest yield) and phytol was found to be the major compound in run 4 (lowest yield). To this end, ALEX was succesfully obtained through Soxhlet extraction and the significant parameters can be further studied to achive optimal yield.
format	Article
author	Hashim, Yumi Zuhanis Has-Yun Mat Jamil, Mohamad Akmal Jamal, Parveen Zainurin, Nur Aimi Aliah Syed Abdul Azzizz, Saripah Salbiah
author_facet	Hashim, Yumi Zuhanis Has-Yun Mat Jamil, Mohamad Akmal Jamal, Parveen Zainurin, Nur Aimi Aliah Syed Abdul Azzizz, Saripah Salbiah
author_sort	Hashim, Yumi Zuhanis Has-Yun
title	Hydrodistillation and soxhlet extraction of agarwood leaf extract from Aquilaria malaccensis
title_short	Hydrodistillation and soxhlet extraction of agarwood leaf extract from Aquilaria malaccensis
title_full	Hydrodistillation and soxhlet extraction of agarwood leaf extract from Aquilaria malaccensis
title_fullStr	Hydrodistillation and soxhlet extraction of agarwood leaf extract from Aquilaria malaccensis
title_full_unstemmed	Hydrodistillation and soxhlet extraction of agarwood leaf extract from Aquilaria malaccensis
title_sort	hydrodistillation and soxhlet extraction of agarwood leaf extract from aquilaria malaccensis
publisher	Universiti Teknologi Malaysia ( UTM )
publishDate	2019
url	http://irep.iium.edu.my/77203/ http://irep.iium.edu.my/77203/ http://irep.iium.edu.my/77203/1/Paper_Hashim%20et%20al%202019%20%28MJFAS%29.pdf http://irep.iium.edu.my/77203/7/77203_Hydrodistillation%20and%20Soxhlet%20extraction_wos.pdf
first_indexed	2023-09-18T21:48:55Z
last_indexed	2023-09-18T21:48:55Z
_version_	1777413637259919360

Hydrodistillation and soxhlet extraction of agarwood leaf extract from Aquilaria malaccensis

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