Zinc intake during the pregnancy increases the proliferation at ventricular zone of the newborn brain

Neurogenesis involves cell proliferation, cell cycle arrest, differentiation, migration and the natural developmental death of the neural precursors. These processes are highly co-ordinated and governed by cell-cycle genes and neural transcription factors. Zn plays a crucial role as a functional...

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Main Authors: Azman, Mohd S., Wan Saudi, Wan S., Ilhami, Mohammad, Abdul Mutalib, Mohd Sokhini, Rahman, Muhammad Tariqur
Format: Article
Language:English
Published: Maney Publishing 2009
Subjects:
Online Access:http://irep.iium.edu.my/806/
http://irep.iium.edu.my/806/
http://irep.iium.edu.my/806/
http://irep.iium.edu.my/806/1/Zinc_intake_during_pregnancy_increases_the_proliferation_at_ventricular_zone_of_the_newborn_brain.pdf
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recordtype eprints
spelling iium-8062011-06-30T07:54:22Z http://irep.iium.edu.my/806/ Zinc intake during the pregnancy increases the proliferation at ventricular zone of the newborn brain Azman, Mohd S. Wan Saudi, Wan S. Ilhami, Mohammad Abdul Mutalib, Mohd Sokhini Rahman, Muhammad Tariqur RG Gynecology and obstetrics Neurogenesis involves cell proliferation, cell cycle arrest, differentiation, migration and the natural developmental death of the neural precursors. These processes are highly co-ordinated and governed by cell-cycle genes and neural transcription factors. Zn plays a crucial role as a functional and structural component of enzymes and transcription factors and components of the intracellular signaling pathway associated with the regulation of cell proliferation. The influence of additional Zn intake during pregnancy on the neuronal proliferation at ventricular zone of the developing fetus has been studied. Pups delivered by the group of mice provided with drinking water with 4.0 mM Zn supplement throughout pregnancy contained an increased number of proliferating neurons in the ventricular zone at P0 compared to those delivered by the mice provided with drinking water without any Zn supplement. This finding provides direct evidence to support the notion that maternal Zn levels influence the development of the nervous system of the offspring. Maney Publishing 2009 Article PeerReviewed application/pdf en http://irep.iium.edu.my/806/1/Zinc_intake_during_pregnancy_increases_the_proliferation_at_ventricular_zone_of_the_newborn_brain.pdf Azman, Mohd S. and Wan Saudi, Wan S. and Ilhami, Mohammad and Abdul Mutalib, Mohd Sokhini and Rahman, Muhammad Tariqur (2009) Zinc intake during the pregnancy increases the proliferation at ventricular zone of the newborn brain. Nutritional Neuroscience, 12 (1). pp. 9-12. ISSN 1476-8305 http://www.maney.co.uk/index.php/journals/nns/?back=1 DOI: 10.1179/147683009X388904
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic RG Gynecology and obstetrics
spellingShingle RG Gynecology and obstetrics
Azman, Mohd S.
Wan Saudi, Wan S.
Ilhami, Mohammad
Abdul Mutalib, Mohd Sokhini
Rahman, Muhammad Tariqur
Zinc intake during the pregnancy increases the proliferation at ventricular zone of the newborn brain
description Neurogenesis involves cell proliferation, cell cycle arrest, differentiation, migration and the natural developmental death of the neural precursors. These processes are highly co-ordinated and governed by cell-cycle genes and neural transcription factors. Zn plays a crucial role as a functional and structural component of enzymes and transcription factors and components of the intracellular signaling pathway associated with the regulation of cell proliferation. The influence of additional Zn intake during pregnancy on the neuronal proliferation at ventricular zone of the developing fetus has been studied. Pups delivered by the group of mice provided with drinking water with 4.0 mM Zn supplement throughout pregnancy contained an increased number of proliferating neurons in the ventricular zone at P0 compared to those delivered by the mice provided with drinking water without any Zn supplement. This finding provides direct evidence to support the notion that maternal Zn levels influence the development of the nervous system of the offspring.
format Article
author Azman, Mohd S.
Wan Saudi, Wan S.
Ilhami, Mohammad
Abdul Mutalib, Mohd Sokhini
Rahman, Muhammad Tariqur
author_facet Azman, Mohd S.
Wan Saudi, Wan S.
Ilhami, Mohammad
Abdul Mutalib, Mohd Sokhini
Rahman, Muhammad Tariqur
author_sort Azman, Mohd S.
title Zinc intake during the pregnancy increases the proliferation at ventricular zone of the newborn brain
title_short Zinc intake during the pregnancy increases the proliferation at ventricular zone of the newborn brain
title_full Zinc intake during the pregnancy increases the proliferation at ventricular zone of the newborn brain
title_fullStr Zinc intake during the pregnancy increases the proliferation at ventricular zone of the newborn brain
title_full_unstemmed Zinc intake during the pregnancy increases the proliferation at ventricular zone of the newborn brain
title_sort zinc intake during the pregnancy increases the proliferation at ventricular zone of the newborn brain
publisher Maney Publishing
publishDate 2009
url http://irep.iium.edu.my/806/
http://irep.iium.edu.my/806/
http://irep.iium.edu.my/806/
http://irep.iium.edu.my/806/1/Zinc_intake_during_pregnancy_increases_the_proliferation_at_ventricular_zone_of_the_newborn_brain.pdf
first_indexed 2023-09-18T20:07:59Z
last_indexed 2023-09-18T20:07:59Z
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