Anti-bacterial and anti-fungal activity of coleus leaves consumed as breast-milk stimulant

The aim of this study was to assess the anti-bacterial and anti-fungal activity of six coleus plants based on their traditional uses (as breast-milk stimulants in some parts of the Asia) from two Asian countries (Malaysia and Indonesia). Plants leaves of coleus species were collected from Kuantan (...

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Bibliographic Details
Main Authors: Khattak, Muhammad Muzaffar Ali Khan, Bakhtiar, M. Taher, Abdul Rahman, Suzanah, Abu Bakar, Ibrahim, Damanik, Muhammad Rizal Martua, Yahaya, Azhary
Format: Article
Language:English
Published: Emerald Group Publishing Limited 2013
Subjects:
Online Access:http://irep.iium.edu.my/8391/
http://irep.iium.edu.my/8391/
http://irep.iium.edu.my/8391/
http://irep.iium.edu.my/8391/1/taher.pdf
Description
Summary:The aim of this study was to assess the anti-bacterial and anti-fungal activity of six coleus plants based on their traditional uses (as breast-milk stimulants in some parts of the Asia) from two Asian countries (Malaysia and Indonesia). Plants leaves of coleus species were collected from Kuantan (Malaysia) and Jakarta (Indonesia). From Kuantan, Coleus aromaticus- Malaysia (CATM), Pogostemon cablin- Malaysia (PCM), Coleus blumei–purple leaves-Malaysia (CBPM), Coleus blumei –red leaves- Malaysia (CBRM), Coleus amboinicus-Malaysia (CALM) and from Jakarta Coleus amboinicus-Indonesia (CALI) were collected freeze dried and extracted with aqueous methanol. The antimicrobial activity of the extract was determined by making use of macro dilution and disc diffusion methods. The selected bacterias and fungus used were namely Bacillus subtilis & Staphylococcus aureus (gram positive) and Escherichia coli & Pseudomonas aeruginosa (gram negative) and Candida albicans(a fungi). All leaf extracts showed activity at least against one strain of bacteria. The results shows that there were significant differences (p<0.05) between the activities on microorganism. The minimum inhibitory concentration (MIC) of all leaves extracts ranged from 1.0–2.0 mg/ml in inhibiting the growth of S. aureus, E. coli, P. aeruginosa and B.subtilis. This study shows that the coleus plants leaves can be used as anti-bacterial anti-fungal agent apart from the breast milk stimulation properties.