Does connecting tobacco cessation intervention with tuberculosis care improve quality of life outcomes?

Does connecting tobacco cessation intervention with tuberculosis care improve quality of life outcomes?

Objectives: The objective of this study was to document the impact of an integrated TB directly observed therapy short-course (DOTS) plus smoking cessation intervention (SCI) on HRQoL. Methods: This was a non-randomized controlled study (quasi experimental design) involving 120 TB patients who we...

Full description

Bibliographic Details
Main Authors: Awaisu, Ahmed, Nik Mohamed, Mohamad Haniki, Noordin, NM, Abd. Aziz, Noorizan, Syed Sulaiman, Syed Azhar, Ahmad Mahayiddin, Aziah, Muttalif, Abdul Razak
Format: Article
Language:English
English
Published: Elsevier Inc. 2011
Subjects:
RA Public aspects of medicine
RM Therapeutics. Pharmacology
Online Access:http://irep.iium.edu.my/8836/
http://irep.iium.edu.my/8836/
http://irep.iium.edu.my/8836/4/PIN96-Poster-TB-Tobacco-QoL-ISPOR-2011-V2.pdf
http://irep.iium.edu.my/8836/7/Value_in_Health.pdf
id iium-8836
recordtype eprints
spelling iium-88362013-06-27T03:47:15Z http://irep.iium.edu.my/8836/ Does connecting tobacco cessation intervention with tuberculosis care improve quality of life outcomes? Awaisu, Ahmed Nik Mohamed, Mohamad Haniki Noordin, NM Abd. Aziz, Noorizan Syed Sulaiman, Syed Azhar Ahmad Mahayiddin, Aziah Muttalif, Abdul Razak RA Public aspects of medicine RM Therapeutics. Pharmacology Objectives: The objective of this study was to document the impact of an integrated TB directly observed therapy short-course (DOTS) plus smoking cessation intervention (SCI) on HRQoL. Methods: This was a non-randomized controlled study (quasi experimental design) involving 120 TB patients who were current smokers at the time of TB diagnosis. Patients were assigned to either of two groups: conventional TB-DOTS plus smoking cessation intervention (SCIDOTS group) or conventional TB-DOTS only (DOTS group). The effects of the novel intervention on HRQoL were measured using EQ-5D questionnaire. Two-way repeated measure ANOVA was used to examine the effects. Results: When compared, participants who received the integrated intervention had a better HRQoL than those who received the conventional TB care. The SCIDOTS group had a significantly greater increase in EQ-5D utility score than the DOTS group during 6 months follow-up (mean± SD = 0.98 ± 0.08 vs. 0.91 ± 0.14, p = 0.006). Similarly, the mean scores for EQ-VAS showed a consistently similar trend as the EQ-5D indices, with the scores increasing over the course of TB treatment. Furthermore, for the EQ-VAS, there were significant main effects for group [F (1, 84) = 4.91, p = 0.029, η2 = 0.06], time [F (2, 168) = 139.50, p = <0.001, η2 = 0.62] and group x time interaction [F (2, 168) = 13.89, p = <0.001, η2 = 0.14]. Conclusions: This study provides evidence that an integrated TB-tobacco treatment strategy could potentially improve overall quality of life outcomes among TB patients who are smokers. Elsevier Inc. 2011 Article PeerReviewed application/pdf en http://irep.iium.edu.my/8836/4/PIN96-Poster-TB-Tobacco-QoL-ISPOR-2011-V2.pdf application/pdf en http://irep.iium.edu.my/8836/7/Value_in_Health.pdf Awaisu, Ahmed and Nik Mohamed, Mohamad Haniki and Noordin, NM and Abd. Aziz, Noorizan and Syed Sulaiman, Syed Azhar and Ahmad Mahayiddin, Aziah and Muttalif, Abdul Razak (2011) Does connecting tobacco cessation intervention with tuberculosis care improve quality of life outcomes? Value in Health, 14 (7). A283. ISSN 1524-4733 (O), 1098-3015 (P) http://www.valueinhealthjournal.com/article/S1098-3015(11)01844-4/fulltext
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
topic RA Public aspects of medicine
RM Therapeutics. Pharmacology
spellingShingle RA Public aspects of medicine
RM Therapeutics. Pharmacology
Awaisu, Ahmed
Nik Mohamed, Mohamad Haniki
Noordin, NM
Abd. Aziz, Noorizan
Syed Sulaiman, Syed Azhar
Ahmad Mahayiddin, Aziah
Muttalif, Abdul Razak
Does connecting tobacco cessation intervention with tuberculosis care improve quality of life outcomes?
description Objectives: The objective of this study was to document the impact of an integrated TB directly observed therapy short-course (DOTS) plus smoking cessation intervention (SCI) on HRQoL. Methods: This was a non-randomized controlled study (quasi experimental design) involving 120 TB patients who were current smokers at the time of TB diagnosis. Patients were assigned to either of two groups: conventional TB-DOTS plus smoking cessation intervention (SCIDOTS group) or conventional TB-DOTS only (DOTS group). The effects of the novel intervention on HRQoL were measured using EQ-5D questionnaire. Two-way repeated measure ANOVA was used to examine the effects. Results: When compared, participants who received the integrated intervention had a better HRQoL than those who received the conventional TB care. The SCIDOTS group had a significantly greater increase in EQ-5D utility score than the DOTS group during 6 months follow-up (mean± SD = 0.98 ± 0.08 vs. 0.91 ± 0.14, p = 0.006). Similarly, the mean scores for EQ-VAS showed a consistently similar trend as the EQ-5D indices, with the scores increasing over the course of TB treatment. Furthermore, for the EQ-VAS, there were significant main effects for group [F (1, 84) = 4.91, p = 0.029, η2 = 0.06], time [F (2, 168) = 139.50, p = <0.001, η2 = 0.62] and group x time interaction [F (2, 168) = 13.89, p = <0.001, η2 = 0.14]. Conclusions: This study provides evidence that an integrated TB-tobacco treatment strategy could potentially improve overall quality of life outcomes among TB patients who are smokers.
format Article
author Awaisu, Ahmed
Nik Mohamed, Mohamad Haniki
Noordin, NM
Abd. Aziz, Noorizan
Syed Sulaiman, Syed Azhar
Ahmad Mahayiddin, Aziah
Muttalif, Abdul Razak
author_facet Awaisu, Ahmed
Nik Mohamed, Mohamad Haniki
Noordin, NM
Abd. Aziz, Noorizan
Syed Sulaiman, Syed Azhar
Ahmad Mahayiddin, Aziah
Muttalif, Abdul Razak
author_sort Awaisu, Ahmed
title Does connecting tobacco cessation intervention with tuberculosis care improve quality of life outcomes?
title_short Does connecting tobacco cessation intervention with tuberculosis care improve quality of life outcomes?
title_full Does connecting tobacco cessation intervention with tuberculosis care improve quality of life outcomes?
title_fullStr Does connecting tobacco cessation intervention with tuberculosis care improve quality of life outcomes?
title_full_unstemmed Does connecting tobacco cessation intervention with tuberculosis care improve quality of life outcomes?
title_sort does connecting tobacco cessation intervention with tuberculosis care improve quality of life outcomes?
publisher Elsevier Inc.
publishDate 2011
url http://irep.iium.edu.my/8836/
http://irep.iium.edu.my/8836/
http://irep.iium.edu.my/8836/4/PIN96-Poster-TB-Tobacco-QoL-ISPOR-2011-V2.pdf
http://irep.iium.edu.my/8836/7/Value_in_Health.pdf
first_indexed 2023-09-18T20:18:39Z
last_indexed 2023-09-18T20:18:39Z
_version_ 1777407958041231360

Similar Items