Impact of Intermittent Screening and Treatment for Malaria among School Children in Kenya : A Cluster Randomized Trial
This paper investigates the effects of intermittent screening and treatment of malaria on the health and education of school children in an area of low-to-moderate malaria transmission. A cluster randomized trial was implemented with 5,233 children...
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| Format: | Policy Research Working Paper |
| Language: | English en_US |
| Published: |
World Bank, Washington, DC
2014
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| Subjects: | |
| Online Access: | http://documents.worldbank.org/curated/en/2014/02/19153553/impact-intermittent-screening-treatment-malaria-among-school-children-kenya-cluster-randomized-trial http://hdl.handle.net/10986/17333 |
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okr-10986-17333 |
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| recordtype |
oai_dc |
| repository_type |
Digital Repository |
| institution_category |
Foreign Institution |
| institution |
Digital Repositories |
| building |
World Bank Open Knowledge Repository |
| collection |
World Bank |
| language |
English en_US |
| topic |
ACADEMIC ACHIEVEMENT ACCESS TO FOOD ACCESS TO TREATMENT ACHIEVEMENT ACHIEVEMENT TESTS ADJUSTMENT ADOLESCENTS AGED AMODIAQUINE ANEMIA ANEMIA CONTROL ANOPHELES MOSQUITOES ANTENATAL CARE ARITHMETIC ATTENTION BASIC EDUCATION BASIC EDUCATION SECTOR BLIND BLOOD SAMPLES BURDEN OF MALARIA CERVICAL CANCER CHILD DEVELOPMENT CHILDHOOD CLASSROOM COGNITION COGNITIVE DEVELOPMENT COGNITIVE IMPAIRMENT COGNITIVE PERFORMANCE COMPARATIVE EDUCATION DEWORMING DIAGNOSIS DIAGNOSTIC TESTS DISEASE DISEASE BURDEN DROWNING DRUG ADMINISTRATION DRUG RESISTANCE DRUG TREATMENT DRUGS EDUCATIONAL ATTAINMENT EDUCATIONAL OUTCOMES EDUCATIONAL PERFORMANCE EFFECTIVE EDUCATION EFFECTIVE TEACHING ENROLLMENT EPIDEMIOLOGY ETHICS EXAM FEMALE ADOLESCENTS FEMALES FREE SCHOOLS GAMETOCYTE CARRIAGE GOVERNMENT PRIMARY SCHOOLS HEADACHE HEALTH FACILITY HEALTH INTERVENTIONS HEALTH OUTCOMES HEALTH SURVEYS HEALTH WORKERS HEMOGLOBIN CONCENTRATION HIGH MALARIA TRANSMISSION HIGH RISK OF INFECTION HIV HUMAN BIOLOGY HYGIENE IMPACT OF MALARIA INFANTS INFECTION INFECTION RATES INFECTIONS INFORMED CONSENT INTERVENTION IRON LEARNING LEUKEMIA LITERACY LITERACY INSTRUCTION LYMPHATIC FILARIASIS MALARIA MALARIA CONTROL MALARIA DIAGNOSIS MALARIA ENDEMIC COUNTRIES MALARIA IN PREGNANCY MALARIA INFECTION MALARIA INFECTIONS MALARIA INTERVENTIONS MALARIA MORBIDITY MALARIA PARASITES MALARIA PREVENTION MALARIA SYMPTOMS MALARIA TRANSMISSION MALARIA TREATMENTS MALARIA-ENDEMIC AREAS MASS SCREENING MEDICAL RESEARCH MENTAL DEVELOPMENT MIGRATION MODELING MORBIDITY MORBIDITY AND MORTALITY MORTALITY MOSQUITO NET NATIONAL SURVEILLANCE NEGATIVE EFFECTS NUMERACY NURSES NUTRITION NUTRITIONAL STATUS OLDER CHILDREN PARASITIC INFECTIONS PARASITOLOGY PARENTAL EDUCATION PNEUMONIA POLYMERASE CHAIN REACTION PREGNANCY PREGNANT WOMEN PREVALENCE PREVENTION OF MALARIA PREVENTIVE TREATMENT PRIMARY SCHOOL PRIMARY SCHOOL ACCESS PRIMARY SCHOOLING PRIMARY SCHOOLS PROPHYLAXIS PUBLIC HEALTH SCHOOL HEALTH SCHOOL QUALITY SCHOOLING SCREENING SEX SIBLINGS SOCIAL SCIENCE RESEARCH STOMACH TEACHER EDUCATION TEACHERS TEACHING METHODS THERAPY TRAUMA TREATMENT TREATMENT OF MALARIA TROPICAL DISEASES TROPICAL MEDICINE VECTORS VOMITING WORKERS YELLOW FEVER Microdata Set |
| spellingShingle |
ACADEMIC ACHIEVEMENT ACCESS TO FOOD ACCESS TO TREATMENT ACHIEVEMENT ACHIEVEMENT TESTS ADJUSTMENT ADOLESCENTS AGED AMODIAQUINE ANEMIA ANEMIA CONTROL ANOPHELES MOSQUITOES ANTENATAL CARE ARITHMETIC ATTENTION BASIC EDUCATION BASIC EDUCATION SECTOR BLIND BLOOD SAMPLES BURDEN OF MALARIA CERVICAL CANCER CHILD DEVELOPMENT CHILDHOOD CLASSROOM COGNITION COGNITIVE DEVELOPMENT COGNITIVE IMPAIRMENT COGNITIVE PERFORMANCE COMPARATIVE EDUCATION DEWORMING DIAGNOSIS DIAGNOSTIC TESTS DISEASE DISEASE BURDEN DROWNING DRUG ADMINISTRATION DRUG RESISTANCE DRUG TREATMENT DRUGS EDUCATIONAL ATTAINMENT EDUCATIONAL OUTCOMES EDUCATIONAL PERFORMANCE EFFECTIVE EDUCATION EFFECTIVE TEACHING ENROLLMENT EPIDEMIOLOGY ETHICS EXAM FEMALE ADOLESCENTS FEMALES FREE SCHOOLS GAMETOCYTE CARRIAGE GOVERNMENT PRIMARY SCHOOLS HEADACHE HEALTH FACILITY HEALTH INTERVENTIONS HEALTH OUTCOMES HEALTH SURVEYS HEALTH WORKERS HEMOGLOBIN CONCENTRATION HIGH MALARIA TRANSMISSION HIGH RISK OF INFECTION HIV HUMAN BIOLOGY HYGIENE IMPACT OF MALARIA INFANTS INFECTION INFECTION RATES INFECTIONS INFORMED CONSENT INTERVENTION IRON LEARNING LEUKEMIA LITERACY LITERACY INSTRUCTION LYMPHATIC FILARIASIS MALARIA MALARIA CONTROL MALARIA DIAGNOSIS MALARIA ENDEMIC COUNTRIES MALARIA IN PREGNANCY MALARIA INFECTION MALARIA INFECTIONS MALARIA INTERVENTIONS MALARIA MORBIDITY MALARIA PARASITES MALARIA PREVENTION MALARIA SYMPTOMS MALARIA TRANSMISSION MALARIA TREATMENTS MALARIA-ENDEMIC AREAS MASS SCREENING MEDICAL RESEARCH MENTAL DEVELOPMENT MIGRATION MODELING MORBIDITY MORBIDITY AND MORTALITY MORTALITY MOSQUITO NET NATIONAL SURVEILLANCE NEGATIVE EFFECTS NUMERACY NURSES NUTRITION NUTRITIONAL STATUS OLDER CHILDREN PARASITIC INFECTIONS PARASITOLOGY PARENTAL EDUCATION PNEUMONIA POLYMERASE CHAIN REACTION PREGNANCY PREGNANT WOMEN PREVALENCE PREVENTION OF MALARIA PREVENTIVE TREATMENT PRIMARY SCHOOL PRIMARY SCHOOL ACCESS PRIMARY SCHOOLING PRIMARY SCHOOLS PROPHYLAXIS PUBLIC HEALTH SCHOOL HEALTH SCHOOL QUALITY SCHOOLING SCREENING SEX SIBLINGS SOCIAL SCIENCE RESEARCH STOMACH TEACHER EDUCATION TEACHERS TEACHING METHODS THERAPY TRAUMA TREATMENT TREATMENT OF MALARIA TROPICAL DISEASES TROPICAL MEDICINE VECTORS VOMITING WORKERS YELLOW FEVER Microdata Set Halliday, Katherine E. Okello, George Turner, Elizabeth L. Njagi, Kiambo Mcharo, Carlos Kengo, Juddy Allen, Elizabeth Dubeck, Margaret M. Jukes, Matthew C.H. Brooker, Simon J. Impact of Intermittent Screening and Treatment for Malaria among School Children in Kenya : A Cluster Randomized Trial |
| geographic_facet |
Africa Kenya |
| relation |
Policy Research Working Paper;No. 6791 |
| description |
This paper investigates the effects of
intermittent screening and treatment of malaria on the
health and education of school children in an area of
low-to-moderate malaria transmission. A cluster randomized
trial was implemented with 5,233 children in 101 government
primary schools on the south coast of Kenya in 2010-12. The
intervention was delivered to children randomly selected
from classes 1 and 5 who were followed up twice across 24
months. Once during each school term, public health workers
used malaria rapid diagnostic tests to screen the children.
Children who tested positive were treated with a six-dose
regimen of artemether-lumefantrine. Given the nature of the
intervention, the trial was not blinded. The primary
outcomes were anemia and sustained attention and the
secondary outcomes were malaria parasitaemia and educational
achievement. The data were analyzed on an intention-to-treat
basis. Anemia in this setting in Kenya, intermittent
screening and treatment, as implemented in this study, is
not effective in improving the health or education of school
children. Possible reasons for the absence of an impact are
the marked geographical heterogeneity in transmission, the
rapid rate of reinfection following artemether-lumefantrine
treatment, the variable reliability of malaria rapid
diagnostic tests, and the relative contribution of malaria
to the etiology of anemia in this setting. |
| format |
Publications & Research :: Policy Research Working Paper |
| author |
Halliday, Katherine E. Okello, George Turner, Elizabeth L. Njagi, Kiambo Mcharo, Carlos Kengo, Juddy Allen, Elizabeth Dubeck, Margaret M. Jukes, Matthew C.H. Brooker, Simon J. |
| author_facet |
Halliday, Katherine E. Okello, George Turner, Elizabeth L. Njagi, Kiambo Mcharo, Carlos Kengo, Juddy Allen, Elizabeth Dubeck, Margaret M. Jukes, Matthew C.H. Brooker, Simon J. |
| author_sort |
Halliday, Katherine E. |
| title |
Impact of Intermittent Screening and Treatment for Malaria among School Children in Kenya : A Cluster Randomized Trial |
| title_short |
Impact of Intermittent Screening and Treatment for Malaria among School Children in Kenya : A Cluster Randomized Trial |
| title_full |
Impact of Intermittent Screening and Treatment for Malaria among School Children in Kenya : A Cluster Randomized Trial |
| title_fullStr |
Impact of Intermittent Screening and Treatment for Malaria among School Children in Kenya : A Cluster Randomized Trial |
| title_full_unstemmed |
Impact of Intermittent Screening and Treatment for Malaria among School Children in Kenya : A Cluster Randomized Trial |
| title_sort |
impact of intermittent screening and treatment for malaria among school children in kenya : a cluster randomized trial |
| publisher |
World Bank, Washington, DC |
| publishDate |
2014 |
| url |
http://documents.worldbank.org/curated/en/2014/02/19153553/impact-intermittent-screening-treatment-malaria-among-school-children-kenya-cluster-randomized-trial http://hdl.handle.net/10986/17333 |
| _version_ |
1764436889285165056 |
| spelling |
okr-10986-173332021-04-23T14:03:37Z Impact of Intermittent Screening and Treatment for Malaria among School Children in Kenya : A Cluster Randomized Trial Halliday, Katherine E. Okello, George Turner, Elizabeth L. Njagi, Kiambo Mcharo, Carlos Kengo, Juddy Allen, Elizabeth Dubeck, Margaret M. Jukes, Matthew C.H. Brooker, Simon J. ACADEMIC ACHIEVEMENT ACCESS TO FOOD ACCESS TO TREATMENT ACHIEVEMENT ACHIEVEMENT TESTS ADJUSTMENT ADOLESCENTS AGED AMODIAQUINE ANEMIA ANEMIA CONTROL ANOPHELES MOSQUITOES ANTENATAL CARE ARITHMETIC ATTENTION BASIC EDUCATION BASIC EDUCATION SECTOR BLIND BLOOD SAMPLES BURDEN OF MALARIA CERVICAL CANCER CHILD DEVELOPMENT CHILDHOOD CLASSROOM COGNITION COGNITIVE DEVELOPMENT COGNITIVE IMPAIRMENT COGNITIVE PERFORMANCE COMPARATIVE EDUCATION DEWORMING DIAGNOSIS DIAGNOSTIC TESTS DISEASE DISEASE BURDEN DROWNING DRUG ADMINISTRATION DRUG RESISTANCE DRUG TREATMENT DRUGS EDUCATIONAL ATTAINMENT EDUCATIONAL OUTCOMES EDUCATIONAL PERFORMANCE EFFECTIVE EDUCATION EFFECTIVE TEACHING ENROLLMENT EPIDEMIOLOGY ETHICS EXAM FEMALE ADOLESCENTS FEMALES FREE SCHOOLS GAMETOCYTE CARRIAGE GOVERNMENT PRIMARY SCHOOLS HEADACHE HEALTH FACILITY HEALTH INTERVENTIONS HEALTH OUTCOMES HEALTH SURVEYS HEALTH WORKERS HEMOGLOBIN CONCENTRATION HIGH MALARIA TRANSMISSION HIGH RISK OF INFECTION HIV HUMAN BIOLOGY HYGIENE IMPACT OF MALARIA INFANTS INFECTION INFECTION RATES INFECTIONS INFORMED CONSENT INTERVENTION IRON LEARNING LEUKEMIA LITERACY LITERACY INSTRUCTION LYMPHATIC FILARIASIS MALARIA MALARIA CONTROL MALARIA DIAGNOSIS MALARIA ENDEMIC COUNTRIES MALARIA IN PREGNANCY MALARIA INFECTION MALARIA INFECTIONS MALARIA INTERVENTIONS MALARIA MORBIDITY MALARIA PARASITES MALARIA PREVENTION MALARIA SYMPTOMS MALARIA TRANSMISSION MALARIA TREATMENTS MALARIA-ENDEMIC AREAS MASS SCREENING MEDICAL RESEARCH MENTAL DEVELOPMENT MIGRATION MODELING MORBIDITY MORBIDITY AND MORTALITY MORTALITY MOSQUITO NET NATIONAL SURVEILLANCE NEGATIVE EFFECTS NUMERACY NURSES NUTRITION NUTRITIONAL STATUS OLDER CHILDREN PARASITIC INFECTIONS PARASITOLOGY PARENTAL EDUCATION PNEUMONIA POLYMERASE CHAIN REACTION PREGNANCY PREGNANT WOMEN PREVALENCE PREVENTION OF MALARIA PREVENTIVE TREATMENT PRIMARY SCHOOL PRIMARY SCHOOL ACCESS PRIMARY SCHOOLING PRIMARY SCHOOLS PROPHYLAXIS PUBLIC HEALTH SCHOOL HEALTH SCHOOL QUALITY SCHOOLING SCREENING SEX SIBLINGS SOCIAL SCIENCE RESEARCH STOMACH TEACHER EDUCATION TEACHERS TEACHING METHODS THERAPY TRAUMA TREATMENT TREATMENT OF MALARIA TROPICAL DISEASES TROPICAL MEDICINE VECTORS VOMITING WORKERS YELLOW FEVER Microdata Set This paper investigates the effects of intermittent screening and treatment of malaria on the health and education of school children in an area of low-to-moderate malaria transmission. A cluster randomized trial was implemented with 5,233 children in 101 government primary schools on the south coast of Kenya in 2010-12. The intervention was delivered to children randomly selected from classes 1 and 5 who were followed up twice across 24 months. Once during each school term, public health workers used malaria rapid diagnostic tests to screen the children. Children who tested positive were treated with a six-dose regimen of artemether-lumefantrine. Given the nature of the intervention, the trial was not blinded. The primary outcomes were anemia and sustained attention and the secondary outcomes were malaria parasitaemia and educational achievement. The data were analyzed on an intention-to-treat basis. Anemia in this setting in Kenya, intermittent screening and treatment, as implemented in this study, is not effective in improving the health or education of school children. Possible reasons for the absence of an impact are the marked geographical heterogeneity in transmission, the rapid rate of reinfection following artemether-lumefantrine treatment, the variable reliability of malaria rapid diagnostic tests, and the relative contribution of malaria to the etiology of anemia in this setting. 2014-03-18T21:32:22Z 2014-03-18T21:32:22Z 2014-02 http://documents.worldbank.org/curated/en/2014/02/19153553/impact-intermittent-screening-treatment-malaria-among-school-children-kenya-cluster-randomized-trial http://hdl.handle.net/10986/17333 English en_US Policy Research Working Paper;No. 6791 CC BY 3.0 IGO http://creativecommons.org/licenses/by/3.0/igo/ World Bank, Washington, DC Publications & Research :: Policy Research Working Paper Publications & Research Africa Kenya |