African Programme for Onchocerciasis Control 1995– 2015 : Updated Health Impact Estimates Based on New Disability Weights

Since 1995, the African Programme for Onchocerciasis Control (APOC) has coordinated mass treatment with ivermectin in 16 sub-Saharan countries (Angola, Burundi, Cameroon, Central African Republic, Chad, Congo, Democratic Republic of Congo, Equatorial Guinea, Ethiopia, Liberia, Malawi, Nigeria, North...

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Bibliographic Details
Main Authors: Coffeng, Luc E., Stolk, Wilma A., Zoure, Honorat G. M., Veerman, J. Lennert, Agblewonu, Koffi B.
Format: Journal Article
Language:en_US
Published: Public Library of Science 2015
Subjects:
Online Access:http://hdl.handle.net/10986/23198
Description
Summary:Since 1995, the African Programme for Onchocerciasis Control (APOC) has coordinated mass treatment with ivermectin in 16 sub-Saharan countries (Angola, Burundi, Cameroon, Central African Republic, Chad, Congo, Democratic Republic of Congo, Equatorial Guinea, Ethiopia, Liberia, Malawi, Nigeria, North Sudan, South Sudan, Uganda, and the United Republic of Tanzania) with the aim to control morbidity due to infection with Onchocerca volvulus, a filarial nematode. Recently, we predicted trends in prevalence of infection, visual impairment, blindness, and troublesome itch due to onchocerciasis in APOC countries for the period 1995–2015, based on extensive data on pre-control infection levels, population coverage of ivermectin mass treatment, and the association between infection and morbidity. We also estimated the associated health impact, expressed in disability-adjusted life years (DALYs).