Synthesis, characterization and biological activity of NitrogenOxygen-Sulfur (NOS) transition metal complexes derived from novel s-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin / Mohd Abdul Fatah Abdul Manan ... [et al.]

A novel Schiff base containing nitrogen-oxygen-sulfur (NOS) donor atoms formed from the condensation reaction of S-2,4dichlorobenzyldithiocarbazate (S-2.4BDTC) with 5-fluroisatin has been synthesized. Complexes of cobalt(ll), nickel(ll), copper(ll), zinc(ll) and cadmium(ll) with this Schiff base hav...

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Main Authors:	Abdul Manan, Mohd Abdul Fatah, Bahron, Hadariah, Kassim, Karimah, Muhamad, Mohd Asrul Hafiz, Sayed Mohamad, Syed Nazmi
Format:	Article
Language:	English
Published:	Research Management Institute (RMI) 2010
Subjects:	Schiff bases Fluoropolymers Metal complexes. Layered double hydroxides
Online Access:	http://ir.uitm.edu.my/id/eprint/12939/ http://ir.uitm.edu.my/id/eprint/12939/1/AJ_MOHD%20ABDUL%20FATAH%20ABDUL%20MANAN%20SRJ%2010%201.pdf

id	uitm-12939
recordtype	eprints
spelling	uitm-129392016-05-30T02:09:45Z http://ir.uitm.edu.my/id/eprint/12939/ Synthesis, characterization and biological activity of NitrogenOxygen-Sulfur (NOS) transition metal complexes derived from novel s-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin / Mohd Abdul Fatah Abdul Manan ... [et al.] Abdul Manan, Mohd Abdul Fatah Bahron, Hadariah Kassim, Karimah Muhamad, Mohd Asrul Hafiz Sayed Mohamad, Syed Nazmi Schiff bases Fluoropolymers Metal complexes. Layered double hydroxides A novel Schiff base containing nitrogen-oxygen-sulfur (NOS) donor atoms formed from the condensation reaction of S-2,4dichlorobenzyldithiocarbazate (S-2.4BDTC) with 5-fluroisatin has been synthesized. Complexes of cobalt(ll), nickel(ll), copper(ll), zinc(ll) and cadmium(ll) with this Schiff base have been prepared and characterized using elemental analysis and various physico-chemical techniques. In the cobalt(ll) andnickel(II) complexes the SchifJbase behaves as a uninegatively charged tridentate nitrogen-oxygen-sulfur (NOS) chelating ligand, bonding through the azomethine nitrogen, thiolate sulfur and carbonylic oxygen of the isatin moiety. However. in the copper(ll), zinc(II) and cadmium(II) complexes the Schiff base behaves as a nitrogen-sulfur (NS) bidentate chelating ligand, bonding through the azomethine nitrogen and thiolate sulfur. The Schiff base and the metal complexes were evaluated with respect to antimicrobial activity, which was performed in reallion to two selected pathogenic microbials (Bacillus subtilis and Pseudomonas aeruginosa). It was observed that only the zinc Schiffbase complex exhibited strong activity against the Bacillus subtilis bacteria with an inhibition zone of 25 mm. Research Management Institute (RMI) 2010 Article PeerReviewed text en http://ir.uitm.edu.my/id/eprint/12939/1/AJ_MOHD%20ABDUL%20FATAH%20ABDUL%20MANAN%20SRJ%2010%201.pdf Abdul Manan, Mohd Abdul Fatah and Bahron, Hadariah and Kassim, Karimah and Muhamad, Mohd Asrul Hafiz and Sayed Mohamad, Syed Nazmi (2010) Synthesis, characterization and biological activity of NitrogenOxygen-Sulfur (NOS) transition metal complexes derived from novel s-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin / Mohd Abdul Fatah Abdul Manan ... [et al.]. Scientific Research Journal, 7 (2). pp. 67-90. ISSN 1675-7009
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Teknologi MARA
building	UiTM Institutional Repository
collection	Online Access
language	English
topic	Schiff bases Fluoropolymers Metal complexes. Layered double hydroxides
spellingShingle	Schiff bases Fluoropolymers Metal complexes. Layered double hydroxides Abdul Manan, Mohd Abdul Fatah Bahron, Hadariah Kassim, Karimah Muhamad, Mohd Asrul Hafiz Sayed Mohamad, Syed Nazmi Synthesis, characterization and biological activity of NitrogenOxygen-Sulfur (NOS) transition metal complexes derived from novel s-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin / Mohd Abdul Fatah Abdul Manan ... [et al.]
description	A novel Schiff base containing nitrogen-oxygen-sulfur (NOS) donor atoms formed from the condensation reaction of S-2,4dichlorobenzyldithiocarbazate (S-2.4BDTC) with 5-fluroisatin has been synthesized. Complexes of cobalt(ll), nickel(ll), copper(ll), zinc(ll) and cadmium(ll) with this Schiff base have been prepared and characterized using elemental analysis and various physico-chemical techniques. In the cobalt(ll) andnickel(II) complexes the SchifJbase behaves as a uninegatively charged tridentate nitrogen-oxygen-sulfur (NOS) chelating ligand, bonding through the azomethine nitrogen, thiolate sulfur and carbonylic oxygen of the isatin moiety. However. in the copper(ll), zinc(II) and cadmium(II) complexes the Schiff base behaves as a nitrogen-sulfur (NS) bidentate chelating ligand, bonding through the azomethine nitrogen and thiolate sulfur. The Schiff base and the metal complexes were evaluated with respect to antimicrobial activity, which was performed in reallion to two selected pathogenic microbials (Bacillus subtilis and Pseudomonas aeruginosa). It was observed that only the zinc Schiffbase complex exhibited strong activity against the Bacillus subtilis bacteria with an inhibition zone of 25 mm.
format	Article
author	Abdul Manan, Mohd Abdul Fatah Bahron, Hadariah Kassim, Karimah Muhamad, Mohd Asrul Hafiz Sayed Mohamad, Syed Nazmi
author_facet	Abdul Manan, Mohd Abdul Fatah Bahron, Hadariah Kassim, Karimah Muhamad, Mohd Asrul Hafiz Sayed Mohamad, Syed Nazmi
author_sort	Abdul Manan, Mohd Abdul Fatah
title	Synthesis, characterization and biological activity of NitrogenOxygen-Sulfur (NOS) transition metal complexes derived from novel s-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin / Mohd Abdul Fatah Abdul Manan ... [et al.]
title_short	Synthesis, characterization and biological activity of NitrogenOxygen-Sulfur (NOS) transition metal complexes derived from novel s-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin / Mohd Abdul Fatah Abdul Manan ... [et al.]
title_full	Synthesis, characterization and biological activity of NitrogenOxygen-Sulfur (NOS) transition metal complexes derived from novel s-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin / Mohd Abdul Fatah Abdul Manan ... [et al.]
title_fullStr	Synthesis, characterization and biological activity of NitrogenOxygen-Sulfur (NOS) transition metal complexes derived from novel s-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin / Mohd Abdul Fatah Abdul Manan ... [et al.]
title_full_unstemmed	Synthesis, characterization and biological activity of NitrogenOxygen-Sulfur (NOS) transition metal complexes derived from novel s-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin / Mohd Abdul Fatah Abdul Manan ... [et al.]
title_sort	synthesis, characterization and biological activity of nitrogenoxygen-sulfur (nos) transition metal complexes derived from novel s-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin / mohd abdul fatah abdul manan ... [et al.]
publisher	Research Management Institute (RMI)
publishDate	2010
url	http://ir.uitm.edu.my/id/eprint/12939/ http://ir.uitm.edu.my/id/eprint/12939/1/AJ_MOHD%20ABDUL%20FATAH%20ABDUL%20MANAN%20SRJ%2010%201.pdf
first_indexed	2023-09-18T22:49:35Z
last_indexed	2023-09-18T22:49:35Z
_version_	1777417454432026624

Synthesis, characterization and biological activity of NitrogenOxygen-Sulfur (NOS) transition metal complexes derived from novel s-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin / Mohd Abdul Fatah Abdul Manan ... [et al.]

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