Chemical constituents of the insecticidal active extract of Tinospora crispa / Nor Aziyah Bakhari, Siti Nur Amirah Diana Fadzillah and Norain Isa

Tinospora crispa Miers (Menispermaceae) is a climbing vine with stems rich in warts. The plant is called Akar Seruntum or Patawali in Malaysia and is widely used for treating skin complaints, malaria, bacterial abscess, high blood pressure and diabetes. In the present study, the stems of T. crispa w...

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Main Authors:	Bakhari, Nor Aziyah, Fadzillah, Siti Nur Amirah Diana, Isa, Norain
Format:	Article
Language:	English
Published:	Research Management Institute (RMI) 2013
Subjects:	Menispermaceae (Moonseed) Alkaloids
Online Access:	http://ir.uitm.edu.my/id/eprint/13042/ http://ir.uitm.edu.my/id/eprint/13042/1/AJ_NOR%20AZIYAH%20BAKHARI%20SRJ%2013%201.pdf

id	uitm-13042
recordtype	eprints
spelling	uitm-130422016-05-30T04:06:04Z http://ir.uitm.edu.my/id/eprint/13042/ Chemical constituents of the insecticidal active extract of Tinospora crispa / Nor Aziyah Bakhari, Siti Nur Amirah Diana Fadzillah and Norain Isa Bakhari, Nor Aziyah Fadzillah, Siti Nur Amirah Diana Isa, Norain Menispermaceae (Moonseed) Alkaloids Tinospora crispa Miers (Menispermaceae) is a climbing vine with stems rich in warts. The plant is called Akar Seruntum or Patawali in Malaysia and is widely used for treating skin complaints, malaria, bacterial abscess, high blood pressure and diabetes. In the present study, the stems of T. crispa were collected from the locality and succesively extracted with petroleum ether, followed by chloroform and ethanol. The insecticidal active extract (ethanol extract) was subjected to column chromatography of silica gel eluted with a gradient mobile phase containing hexane, chloroform and ethanol. Among the chemical constituents isolated are n-tetracosyl trans-ferulate and n-octacosyl alcohol, along with three known aporphine alkaloids; N-formylnornuciferine, N-acetylnornuciferine and lysicamine. All compounds were identified by comparing their spectroscopic data (UV, IR, 1H NMR, MS) with data from corresponding values in the literature. Isolation of n-tetracosyl trans-ferulate and n-octacosyl alcohol is reported the first time for T. crispa. Research Management Institute (RMI) 2013 Article PeerReviewed text en http://ir.uitm.edu.my/id/eprint/13042/1/AJ_NOR%20AZIYAH%20BAKHARI%20SRJ%2013%201.pdf Bakhari, Nor Aziyah and Fadzillah, Siti Nur Amirah Diana and Isa, Norain (2013) Chemical constituents of the insecticidal active extract of Tinospora crispa / Nor Aziyah Bakhari, Siti Nur Amirah Diana Fadzillah and Norain Isa. Scientific Research Journal, 10 (1). pp. 23-35. ISSN 1675-7009
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Teknologi MARA
building	UiTM Institutional Repository
collection	Online Access
language	English
topic	Menispermaceae (Moonseed) Alkaloids
spellingShingle	Menispermaceae (Moonseed) Alkaloids Bakhari, Nor Aziyah Fadzillah, Siti Nur Amirah Diana Isa, Norain Chemical constituents of the insecticidal active extract of Tinospora crispa / Nor Aziyah Bakhari, Siti Nur Amirah Diana Fadzillah and Norain Isa
description	Tinospora crispa Miers (Menispermaceae) is a climbing vine with stems rich in warts. The plant is called Akar Seruntum or Patawali in Malaysia and is widely used for treating skin complaints, malaria, bacterial abscess, high blood pressure and diabetes. In the present study, the stems of T. crispa were collected from the locality and succesively extracted with petroleum ether, followed by chloroform and ethanol. The insecticidal active extract (ethanol extract) was subjected to column chromatography of silica gel eluted with a gradient mobile phase containing hexane, chloroform and ethanol. Among the chemical constituents isolated are n-tetracosyl trans-ferulate and n-octacosyl alcohol, along with three known aporphine alkaloids; N-formylnornuciferine, N-acetylnornuciferine and lysicamine. All compounds were identified by comparing their spectroscopic data (UV, IR, 1H NMR, MS) with data from corresponding values in the literature. Isolation of n-tetracosyl trans-ferulate and n-octacosyl alcohol is reported the first time for T. crispa.
format	Article
author	Bakhari, Nor Aziyah Fadzillah, Siti Nur Amirah Diana Isa, Norain
author_facet	Bakhari, Nor Aziyah Fadzillah, Siti Nur Amirah Diana Isa, Norain
author_sort	Bakhari, Nor Aziyah
title	Chemical constituents of the insecticidal active extract of Tinospora crispa / Nor Aziyah Bakhari, Siti Nur Amirah Diana Fadzillah and Norain Isa
title_short	Chemical constituents of the insecticidal active extract of Tinospora crispa / Nor Aziyah Bakhari, Siti Nur Amirah Diana Fadzillah and Norain Isa
title_full	Chemical constituents of the insecticidal active extract of Tinospora crispa / Nor Aziyah Bakhari, Siti Nur Amirah Diana Fadzillah and Norain Isa
title_fullStr	Chemical constituents of the insecticidal active extract of Tinospora crispa / Nor Aziyah Bakhari, Siti Nur Amirah Diana Fadzillah and Norain Isa
title_full_unstemmed	Chemical constituents of the insecticidal active extract of Tinospora crispa / Nor Aziyah Bakhari, Siti Nur Amirah Diana Fadzillah and Norain Isa
title_sort	chemical constituents of the insecticidal active extract of tinospora crispa / nor aziyah bakhari, siti nur amirah diana fadzillah and norain isa
publisher	Research Management Institute (RMI)
publishDate	2013
url	http://ir.uitm.edu.my/id/eprint/13042/ http://ir.uitm.edu.my/id/eprint/13042/1/AJ_NOR%20AZIYAH%20BAKHARI%20SRJ%2013%201.pdf
first_indexed	2023-09-18T22:49:44Z
last_indexed	2023-09-18T22:49:44Z
_version_	1777417463402594304

Chemical constituents of the insecticidal active extract of Tinospora crispa / Nor Aziyah Bakhari, Siti Nur Amirah Diana Fadzillah and Norain Isa

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