Prevalence of comorbidities & risk factors for Multidrug Resistance among Tuberculosis patients in Institute of Respiratory Medicine, Kuala Lumpur / Alia Azmi

Globally, the issue of Multidrug Resistant Tuberculosis (MDR-TB) was acknowledged as a threat to the successful prevention and treatment of TB. In Malaysia, TB remains a major health issue and incidence has been rising slowly for the past decade indicating poor success rate in current TB control pr...

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Main Author:	Azmi, Alia
Format:	Thesis
Language:	English
Published:	2013
Subjects:	Building fittings and their installation Building control systems
Online Access:	http://ir.uitm.edu.my/id/eprint/15474/ http://ir.uitm.edu.my/id/eprint/15474/1/TM_ALIA%20AZMI%20HS%2013_5.PDF

id	uitm-15474
recordtype	eprints
spelling	uitm-154742016-11-23T06:56:14Z http://ir.uitm.edu.my/id/eprint/15474/ Prevalence of comorbidities & risk factors for Multidrug Resistance among Tuberculosis patients in Institute of Respiratory Medicine, Kuala Lumpur / Alia Azmi Azmi, Alia Building fittings and their installation Building control systems Globally, the issue of Multidrug Resistant Tuberculosis (MDR-TB) was acknowledged as a threat to the successful prevention and treatment of TB. In Malaysia, TB remains a major health issue and incidence has been rising slowly for the past decade indicating poor success rate in current TB control programme. Currently, very little epidemiological data can be found regarding the situation of TB and MDR-TB in Malaysia. Therefore, this study aims to bridge the gap in information regarding TB and MDR-TB by identifying the population at risk. The objective of this study is also to identify the independent risk factors associated with MDR-TB in Malaysia. 477 TB patients from the Institute of Respiratory Medicine (IPR) were universally sampled based on the records of patients in 2010. Among 477 patients sampled, 67.9% were male with mean age 37.2 (SD 14.9). 30% of patients were foreign born with the majority were from Myanmar (14.9%), Indonesia (9.4%) and Bangladesh (2.7%). Prevalence of TB/HIV and TB/Diabetes among the patients sampled was 0.059 and 0.155 respectively. In multivariate analysis, BCG Status (AOR=0.292, 95%CI 0.13-0.67) was found to be a protective risk factor while history of previous TB (AOR=4.36, 95%CI 1.80-10.56) was a risk factor for MDR-TB.Whilst history of previous TB is a commonly acknowledged risk factor, the evidence of BCG as a protective factor for MDR-TB indicates that BCG vaccination is still a viable preventive measure. Association was found between BCG Status and foreign bom patients (p-value <0.01) indicating a need for active screening of immigrants. 2013 Thesis NonPeerReviewed text en http://ir.uitm.edu.my/id/eprint/15474/1/TM_ALIA%20AZMI%20HS%2013_5.PDF Azmi, Alia (2013) Prevalence of comorbidities & risk factors for Multidrug Resistance among Tuberculosis patients in Institute of Respiratory Medicine, Kuala Lumpur / Alia Azmi. Masters thesis, Universiti Teknologi MARA.
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Teknologi MARA
building	UiTM Institutional Repository
collection	Online Access
language	English
topic	Building fittings and their installation Building control systems
spellingShingle	Building fittings and their installation Building control systems Azmi, Alia Prevalence of comorbidities & risk factors for Multidrug Resistance among Tuberculosis patients in Institute of Respiratory Medicine, Kuala Lumpur / Alia Azmi
description	Globally, the issue of Multidrug Resistant Tuberculosis (MDR-TB) was acknowledged as a threat to the successful prevention and treatment of TB. In Malaysia, TB remains a major health issue and incidence has been rising slowly for the past decade indicating poor success rate in current TB control programme. Currently, very little epidemiological data can be found regarding the situation of TB and MDR-TB in Malaysia. Therefore, this study aims to bridge the gap in information regarding TB and MDR-TB by identifying the population at risk. The objective of this study is also to identify the independent risk factors associated with MDR-TB in Malaysia. 477 TB patients from the Institute of Respiratory Medicine (IPR) were universally sampled based on the records of patients in 2010. Among 477 patients sampled, 67.9% were male with mean age 37.2 (SD 14.9). 30% of patients were foreign born with the majority were from Myanmar (14.9%), Indonesia (9.4%) and Bangladesh (2.7%). Prevalence of TB/HIV and TB/Diabetes among the patients sampled was 0.059 and 0.155 respectively. In multivariate analysis, BCG Status (AOR=0.292, 95%CI 0.13-0.67) was found to be a protective risk factor while history of previous TB (AOR=4.36, 95%CI 1.80-10.56) was a risk factor for MDR-TB.Whilst history of previous TB is a commonly acknowledged risk factor, the evidence of BCG as a protective factor for MDR-TB indicates that BCG vaccination is still a viable preventive measure. Association was found between BCG Status and foreign bom patients (p-value <0.01) indicating a need for active screening of immigrants.
format	Thesis
author	Azmi, Alia
author_facet	Azmi, Alia
author_sort	Azmi, Alia
title	Prevalence of comorbidities & risk factors for Multidrug Resistance among Tuberculosis patients in Institute of Respiratory Medicine, Kuala Lumpur / Alia Azmi
title_short	Prevalence of comorbidities & risk factors for Multidrug Resistance among Tuberculosis patients in Institute of Respiratory Medicine, Kuala Lumpur / Alia Azmi
title_full	Prevalence of comorbidities & risk factors for Multidrug Resistance among Tuberculosis patients in Institute of Respiratory Medicine, Kuala Lumpur / Alia Azmi
title_fullStr	Prevalence of comorbidities & risk factors for Multidrug Resistance among Tuberculosis patients in Institute of Respiratory Medicine, Kuala Lumpur / Alia Azmi
title_full_unstemmed	Prevalence of comorbidities & risk factors for Multidrug Resistance among Tuberculosis patients in Institute of Respiratory Medicine, Kuala Lumpur / Alia Azmi
title_sort	prevalence of comorbidities & risk factors for multidrug resistance among tuberculosis patients in institute of respiratory medicine, kuala lumpur / alia azmi
publishDate	2013
url	http://ir.uitm.edu.my/id/eprint/15474/ http://ir.uitm.edu.my/id/eprint/15474/1/TM_ALIA%20AZMI%20HS%2013_5.PDF
first_indexed	2023-09-18T22:53:56Z
last_indexed	2023-09-18T22:53:56Z
_version_	1777417727470731264

Prevalence of comorbidities & risk factors for Multidrug Resistance among Tuberculosis patients in Institute of Respiratory Medicine, Kuala Lumpur / Alia Azmi

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