Detection of metabolomic profile of saliva in healthy Malaysian adults / Han Hing Lee … [et al.]

Background: Saliva is a readily accessible biofluid that is important for the overall quality of life, functionally essential in the chewing, swallowing, tasting, regulation mouth flora and prevention of caries. The aim of this study is to assess the global metabolomic profile of saliva in healthy M...

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Main Author:	Han Hing Lee
Format:	Article
Language:	English
Published:	Faculty of Dentistry 2015
Online Access:	http://ir.uitm.edu.my/id/eprint/18346/ http://ir.uitm.edu.my/id/eprint/18346/2/AJ_HAN%20HING%20LEE%20COS%2015.pdf

id	uitm-18346
recordtype	eprints
spelling	uitm-183462019-07-03T07:15:12Z http://ir.uitm.edu.my/id/eprint/18346/ Detection of metabolomic profile of saliva in healthy Malaysian adults / Han Hing Lee … [et al.] Han Hing Lee Background: Saliva is a readily accessible biofluid that is important for the overall quality of life, functionally essential in the chewing, swallowing, tasting, regulation mouth flora and prevention of caries. The aim of this study is to assess the global metabolomic profile of saliva in healthy Malaysian adults. Methods: As a first step to determining and understanding the metabolomic profile of saliva in healthy Malaysian adults, we have collected saliva samples of 50 adults and measured the salivary metabolite to establish a profiling metabolite data, Human Metabolome Database (HMDB). Metabolites concentrations of saliva in healthy subjects were measured by using 1H NMR spectroscopy. Results: The results showed there was no significant inter-individual variations of the key metabolites observed among the healthy Malaysian adults and there was no significant variation of the metabolites between female and male subjects. Conclusion: The metabolomic profile of saliva in healthy Malaysian adults could be used to establish the metabolomic database and used as a comparison for future study of the saliva of specific diseases. Faculty of Dentistry 2015 Article PeerReviewed text en http://ir.uitm.edu.my/id/eprint/18346/2/AJ_HAN%20HING%20LEE%20COS%2015.pdf Han Hing Lee (2015) Detection of metabolomic profile of saliva in healthy Malaysian adults / Han Hing Lee … [et al.]. Compendium of Oral Science (Compend. Oral Sci.), 1. pp. 40-46. ISSN 2489-1102
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Teknologi MARA
building	UiTM Institutional Repository
collection	Online Access
language	English
description	Background: Saliva is a readily accessible biofluid that is important for the overall quality of life, functionally essential in the chewing, swallowing, tasting, regulation mouth flora and prevention of caries. The aim of this study is to assess the global metabolomic profile of saliva in healthy Malaysian adults. Methods: As a first step to determining and understanding the metabolomic profile of saliva in healthy Malaysian adults, we have collected saliva samples of 50 adults and measured the salivary metabolite to establish a profiling metabolite data, Human Metabolome Database (HMDB). Metabolites concentrations of saliva in healthy subjects were measured by using 1H NMR spectroscopy. Results: The results showed there was no significant inter-individual variations of the key metabolites observed among the healthy Malaysian adults and there was no significant variation of the metabolites between female and male subjects. Conclusion: The metabolomic profile of saliva in healthy Malaysian adults could be used to establish the metabolomic database and used as a comparison for future study of the saliva of specific diseases.
format	Article
author	Han Hing Lee
spellingShingle	Han Hing Lee Detection of metabolomic profile of saliva in healthy Malaysian adults / Han Hing Lee … [et al.]
author_facet	Han Hing Lee
author_sort	Han Hing Lee
title	Detection of metabolomic profile of saliva in healthy Malaysian adults / Han Hing Lee … [et al.]
title_short	Detection of metabolomic profile of saliva in healthy Malaysian adults / Han Hing Lee … [et al.]
title_full	Detection of metabolomic profile of saliva in healthy Malaysian adults / Han Hing Lee … [et al.]
title_fullStr	Detection of metabolomic profile of saliva in healthy Malaysian adults / Han Hing Lee … [et al.]
title_full_unstemmed	Detection of metabolomic profile of saliva in healthy Malaysian adults / Han Hing Lee … [et al.]
title_sort	detection of metabolomic profile of saliva in healthy malaysian adults / han hing lee … [et al.]
publisher	Faculty of Dentistry
publishDate	2015
url	http://ir.uitm.edu.my/id/eprint/18346/ http://ir.uitm.edu.my/id/eprint/18346/2/AJ_HAN%20HING%20LEE%20COS%2015.pdf
first_indexed	2023-09-18T23:00:19Z
last_indexed	2023-09-18T23:00:19Z
_version_	1777418129193828352

Detection of metabolomic profile of saliva in healthy Malaysian adults / Han Hing Lee … [et al.]

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