New modules and assembled systems for the controlled release of drugs in combination / Camillo Benetti

New modules and assembled systems for the controlled release of drugs in combination / Camillo Benetti

Dome Matrix technology is a platform for the controlled release of drug. This technology is based on the assembling of modules used as elements for controlling the drug release. The research project of the doctorate thesis was devoted to the application of Dome Matrix technology for the preparation...

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Bibliographic Details
Main Author: Camillo, Benetti
Format: Book Section
Language:English
Published: Institute of Graduate Studies, UiTM 2016
Subjects:
Malaysia
Online Access:http://ir.uitm.edu.my/id/eprint/19907/
http://ir.uitm.edu.my/id/eprint/19907/1/ABS_CAMILLO%20BENETTI%20TDRA%20VOL%2010%20IGS%2016.pdf
id uitm-19907
recordtype eprints
spelling uitm-199072018-06-08T03:59:22Z http://ir.uitm.edu.my/id/eprint/19907/ New modules and assembled systems for the controlled release of drugs in combination / Camillo Benetti Camillo, Benetti Malaysia Dome Matrix technology is a platform for the controlled release of drug. This technology is based on the assembling of modules used as elements for controlling the drug release. The research project of the doctorate thesis was devoted to the application of Dome Matrix technology for the preparation of gastro-retentive dosage forms thanks to the module assembly in void configuration. According to the co-tutorship agreement, the research was carried out both at University of Parma and University Teknologi MARA, Kuala Lumpur. During the first part of the project, carried out at University of Parma, a modular assembled system for a double pulse release (immediate and delayed release) of esomeprazole in combination with sucralfate was studied. The assembled system was build up by assembling 5 modules, three sucralfate modules and two esomeprazole modules, in “mixed” configuration (void and stacked configurations) with three different release kinetics. The alkalizing agent in the esomeprazole immediate release module prevented the degradation of the drug in acid environment in vitro… Institute of Graduate Studies, UiTM 2016 Book Section PeerReviewed text en http://ir.uitm.edu.my/id/eprint/19907/1/ABS_CAMILLO%20BENETTI%20TDRA%20VOL%2010%20IGS%2016.pdf Camillo, Benetti (2016) New modules and assembled systems for the controlled release of drugs in combination / Camillo Benetti. In: The Doctoral Research Abstracts. IGS Biannual Publication, 10 (10). Institute of Graduate Studies, UiTM, Shah Alam.
repository_type Digital Repository
institution_category Local University
institution Universiti Teknologi MARA
building UiTM Institutional Repository
collection Online Access
language English
topic Malaysia
spellingShingle Malaysia
Camillo, Benetti
New modules and assembled systems for the controlled release of drugs in combination / Camillo Benetti
description Dome Matrix technology is a platform for the controlled release of drug. This technology is based on the assembling of modules used as elements for controlling the drug release. The research project of the doctorate thesis was devoted to the application of Dome Matrix technology for the preparation of gastro-retentive dosage forms thanks to the module assembly in void configuration. According to the co-tutorship agreement, the research was carried out both at University of Parma and University Teknologi MARA, Kuala Lumpur. During the first part of the project, carried out at University of Parma, a modular assembled system for a double pulse release (immediate and delayed release) of esomeprazole in combination with sucralfate was studied. The assembled system was build up by assembling 5 modules, three sucralfate modules and two esomeprazole modules, in “mixed” configuration (void and stacked configurations) with three different release kinetics. The alkalizing agent in the esomeprazole immediate release module prevented the degradation of the drug in acid environment in vitro…
format Book Section
author Camillo, Benetti
author_facet Camillo, Benetti
author_sort Camillo, Benetti
title New modules and assembled systems for the controlled release of drugs in combination / Camillo Benetti
title_short New modules and assembled systems for the controlled release of drugs in combination / Camillo Benetti
title_full New modules and assembled systems for the controlled release of drugs in combination / Camillo Benetti
title_fullStr New modules and assembled systems for the controlled release of drugs in combination / Camillo Benetti
title_full_unstemmed New modules and assembled systems for the controlled release of drugs in combination / Camillo Benetti
title_sort new modules and assembled systems for the controlled release of drugs in combination / camillo benetti
publisher Institute of Graduate Studies, UiTM
publishDate 2016
url http://ir.uitm.edu.my/id/eprint/19907/
http://ir.uitm.edu.my/id/eprint/19907/1/ABS_CAMILLO%20BENETTI%20TDRA%20VOL%2010%20IGS%2016.pdf
first_indexed 2023-09-18T23:03:33Z
last_indexed 2023-09-18T23:03:33Z
_version_ 1777418332443508736

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