Optimisation of oleanolic acid extraction from pokok bunga tahi ayam' (Lantana Camara) roots by methanol-ethyl acetate solvent using resronse surface methodology / Rasimah Mahat

Lantana camara is an ornamental plant used in tradition medicine for the treatment of various diseases. The roots of L. camara is a rich of oleanolic acid which has shown anti-inflammatory, hepatoprotective, antitumor, antioxidant and antihyperliperdemic activity. Optimisation of various extraction...

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Main Author:	Mahat, Rasimah
Format:	Student Project
Language:	English
Published:	Faculty of Applied Sciences 2009
Subjects:	Aromatic compounds Extraction
Online Access:	http://ir.uitm.edu.my/id/eprint/22950/ http://ir.uitm.edu.my/id/eprint/22950/1/PPb_RASIMAH%20MAHAT%20AS%2008_5.pdf

id	uitm-22950
recordtype	eprints
spelling	uitm-229502019-01-29T04:45:33Z http://ir.uitm.edu.my/id/eprint/22950/ Optimisation of oleanolic acid extraction from pokok bunga tahi ayam' (Lantana Camara) roots by methanol-ethyl acetate solvent using resronse surface methodology / Rasimah Mahat Mahat, Rasimah Aromatic compounds Extraction Lantana camara is an ornamental plant used in tradition medicine for the treatment of various diseases. The roots of L. camara is a rich of oleanolic acid which has shown anti-inflammatory, hepatoprotective, antitumor, antioxidant and antihyperliperdemic activity. Optimisation of various extraction parameters using response surface methodology (RSM) was performed to asses maximum yield of oleanolic acid from L.camara roots. MINITAB software version 14 was used to identify the significant effect of various extraction parameters such as concentration of solvent-solid ratio (mL:g), extraction temperature and extraction time. Among the three variables tested, concentration of solvent-solid ratio (mL:g) and extraction temperature were found to have significant effect on oleanolic acid extraction. Optimum level of the significant variables were determined by using central composite design. The optimum condition for extraction of oleanolic acid was found at 30 mL/g of concentration of solvent-solid ratio, 60QC of extraction temperature and 30 minutesof extraction time. At optimum extraction parameters, the optimum yield of oleanolic acid obtained experimentally (1.36609 %) was found to be very close to its predicted value determined by (1.2915%) MINITAB software version 14. Faculty of Applied Sciences 2009 Student Project NonPeerReviewed text en http://ir.uitm.edu.my/id/eprint/22950/1/PPb_RASIMAH%20MAHAT%20AS%2008_5.pdf Mahat, Rasimah (2009) Optimisation of oleanolic acid extraction from pokok bunga tahi ayam' (Lantana Camara) roots by methanol-ethyl acetate solvent using resronse surface methodology / Rasimah Mahat. [Student Project] (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Teknologi MARA
building	UiTM Institutional Repository
collection	Online Access
language	English
topic	Aromatic compounds Extraction
spellingShingle	Aromatic compounds Extraction Mahat, Rasimah Optimisation of oleanolic acid extraction from pokok bunga tahi ayam' (Lantana Camara) roots by methanol-ethyl acetate solvent using resronse surface methodology / Rasimah Mahat
description	Lantana camara is an ornamental plant used in tradition medicine for the treatment of various diseases. The roots of L. camara is a rich of oleanolic acid which has shown anti-inflammatory, hepatoprotective, antitumor, antioxidant and antihyperliperdemic activity. Optimisation of various extraction parameters using response surface methodology (RSM) was performed to asses maximum yield of oleanolic acid from L.camara roots. MINITAB software version 14 was used to identify the significant effect of various extraction parameters such as concentration of solvent-solid ratio (mL:g), extraction temperature and extraction time. Among the three variables tested, concentration of solvent-solid ratio (mL:g) and extraction temperature were found to have significant effect on oleanolic acid extraction. Optimum level of the significant variables were determined by using central composite design. The optimum condition for extraction of oleanolic acid was found at 30 mL/g of concentration of solvent-solid ratio, 60QC of extraction temperature and 30 minutesof extraction time. At optimum extraction parameters, the optimum yield of oleanolic acid obtained experimentally (1.36609 %) was found to be very close to its predicted value determined by (1.2915%) MINITAB software version 14.
format	Student Project
author	Mahat, Rasimah
author_facet	Mahat, Rasimah
author_sort	Mahat, Rasimah
title	Optimisation of oleanolic acid extraction from pokok bunga tahi ayam' (Lantana Camara) roots by methanol-ethyl acetate solvent using resronse surface methodology / Rasimah Mahat
title_short	Optimisation of oleanolic acid extraction from pokok bunga tahi ayam' (Lantana Camara) roots by methanol-ethyl acetate solvent using resronse surface methodology / Rasimah Mahat
title_full	Optimisation of oleanolic acid extraction from pokok bunga tahi ayam' (Lantana Camara) roots by methanol-ethyl acetate solvent using resronse surface methodology / Rasimah Mahat
title_fullStr	Optimisation of oleanolic acid extraction from pokok bunga tahi ayam' (Lantana Camara) roots by methanol-ethyl acetate solvent using resronse surface methodology / Rasimah Mahat
title_full_unstemmed	Optimisation of oleanolic acid extraction from pokok bunga tahi ayam' (Lantana Camara) roots by methanol-ethyl acetate solvent using resronse surface methodology / Rasimah Mahat
title_sort	optimisation of oleanolic acid extraction from pokok bunga tahi ayam' (lantana camara) roots by methanol-ethyl acetate solvent using resronse surface methodology / rasimah mahat
publisher	Faculty of Applied Sciences
publishDate	2009
url	http://ir.uitm.edu.my/id/eprint/22950/ http://ir.uitm.edu.my/id/eprint/22950/1/PPb_RASIMAH%20MAHAT%20AS%2008_5.pdf
first_indexed	2023-09-18T23:09:46Z
last_indexed	2023-09-18T23:09:46Z
_version_	1777418723663020032

Optimisation of oleanolic acid extraction from pokok bunga tahi ayam' (Lantana Camara) roots by methanol-ethyl acetate solvent using resronse surface methodology / Rasimah Mahat

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