Evaluation of antimicrobial properties and toxicity of nephelium lappaceum l. extract / Izzah Izzati Nodin

A study has being conducted on the Nephelium lappaceum L. leaves methanolic extract. The study aims to evaluate the antimicrobial activity of methanolic extract of the N. lappaceum L. leaves and to evaluate the acute toxicity properties of methanolic extract of N. lappaceum L. leaves. All different...

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Main Author:	Nodin, Izzah Izzati
Format:	Student Project
Language:	English
Published:	Faculty of Applied Sciences 2016
Subjects:	QR Microbiology Bacteria
Online Access:	http://ir.uitm.edu.my/id/eprint/24471/ http://ir.uitm.edu.my/id/eprint/24471/1/PPb_IZZAH%20IZZATI%20NODIN%20AS%20N%2016_5.pdf

id	uitm-24471
recordtype	eprints
spelling	uitm-244712019-06-20T06:07:57Z http://ir.uitm.edu.my/id/eprint/24471/ Evaluation of antimicrobial properties and toxicity of nephelium lappaceum l. extract / Izzah Izzati Nodin Nodin, Izzah Izzati QR Microbiology Bacteria A study has being conducted on the Nephelium lappaceum L. leaves methanolic extract. The study aims to evaluate the antimicrobial activity of methanolic extract of the N. lappaceum L. leaves and to evaluate the acute toxicity properties of methanolic extract of N. lappaceum L. leaves. All different concentration of extract ranging from 50 mg/ml, 100 mg/ml, 200 mg/ml, 300 mg/ml and 400 mg/ml were tested against Gram-positive bacteria, Bacillus subtilis, Staphylococcus aureus and Gram-negative bacteria, Escherichia coli, Pseudomonas aeruginosa. The antimicrobial activities of the extract were determined by the disc diffusion method, mimimum inhibitory concentration method and minimum bactericidal concentration method. Zone of inhibition of extracts were compared with the standard antibiotic, Streptomycin which acts as positive control, while DMSO (10%) used as negative control. The highest antimicrobial activity exhibited against P.aeruginosa which was about 17.3 mm ± 1.53 compared to E.coli which did not show any activity. The lowest minimum inhibitory concentrations were 50 mg/ml against P.aeruginosa, B.subtilis, and S.aureus. The lowest minimum bactericidal concentrations taken were 50 mg/ml which showed against P.aeruginosa. The toxicity test also tested on Artemia salina and resulted that the LC50 value which is 3.16 mg/ml as compared to 1.0 mg/ml, thus the extract is not toxic. Faculty of Applied Sciences 2016 Student Project NonPeerReviewed text en http://ir.uitm.edu.my/id/eprint/24471/1/PPb_IZZAH%20IZZATI%20NODIN%20AS%20N%2016_5.pdf Nodin, Izzah Izzati (2016) Evaluation of antimicrobial properties and toxicity of nephelium lappaceum l. extract / Izzah Izzati Nodin. [Student Project] (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Teknologi MARA
building	UiTM Institutional Repository
collection	Online Access
language	English
topic	QR Microbiology Bacteria
spellingShingle	QR Microbiology Bacteria Nodin, Izzah Izzati Evaluation of antimicrobial properties and toxicity of nephelium lappaceum l. extract / Izzah Izzati Nodin
description	A study has being conducted on the Nephelium lappaceum L. leaves methanolic extract. The study aims to evaluate the antimicrobial activity of methanolic extract of the N. lappaceum L. leaves and to evaluate the acute toxicity properties of methanolic extract of N. lappaceum L. leaves. All different concentration of extract ranging from 50 mg/ml, 100 mg/ml, 200 mg/ml, 300 mg/ml and 400 mg/ml were tested against Gram-positive bacteria, Bacillus subtilis, Staphylococcus aureus and Gram-negative bacteria, Escherichia coli, Pseudomonas aeruginosa. The antimicrobial activities of the extract were determined by the disc diffusion method, mimimum inhibitory concentration method and minimum bactericidal concentration method. Zone of inhibition of extracts were compared with the standard antibiotic, Streptomycin which acts as positive control, while DMSO (10%) used as negative control. The highest antimicrobial activity exhibited against P.aeruginosa which was about 17.3 mm ± 1.53 compared to E.coli which did not show any activity. The lowest minimum inhibitory concentrations were 50 mg/ml against P.aeruginosa, B.subtilis, and S.aureus. The lowest minimum bactericidal concentrations taken were 50 mg/ml which showed against P.aeruginosa. The toxicity test also tested on Artemia salina and resulted that the LC50 value which is 3.16 mg/ml as compared to 1.0 mg/ml, thus the extract is not toxic.
format	Student Project
author	Nodin, Izzah Izzati
author_facet	Nodin, Izzah Izzati
author_sort	Nodin, Izzah Izzati
title	Evaluation of antimicrobial properties and toxicity of nephelium lappaceum l. extract / Izzah Izzati Nodin
title_short	Evaluation of antimicrobial properties and toxicity of nephelium lappaceum l. extract / Izzah Izzati Nodin
title_full	Evaluation of antimicrobial properties and toxicity of nephelium lappaceum l. extract / Izzah Izzati Nodin
title_fullStr	Evaluation of antimicrobial properties and toxicity of nephelium lappaceum l. extract / Izzah Izzati Nodin
title_full_unstemmed	Evaluation of antimicrobial properties and toxicity of nephelium lappaceum l. extract / Izzah Izzati Nodin
title_sort	evaluation of antimicrobial properties and toxicity of nephelium lappaceum l. extract / izzah izzati nodin
publisher	Faculty of Applied Sciences
publishDate	2016
url	http://ir.uitm.edu.my/id/eprint/24471/ http://ir.uitm.edu.my/id/eprint/24471/1/PPb_IZZAH%20IZZATI%20NODIN%20AS%20N%2016_5.pdf
first_indexed	2023-09-18T23:12:39Z
last_indexed	2023-09-18T23:12:39Z
_version_	1777418905539575808

Evaluation of antimicrobial properties and toxicity of nephelium lappaceum l. extract / Izzah Izzati Nodin

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