Chemical constituents from the twig of jasminum sambac and its antioxidant activity / Siti Nazira Sulaiman

Jasminum sambac or J. sambac is a plant species from family of Oleaceae which widely cultivated throughout Malaysia. The twig, stem, flowers and roots of the plant used traditionally in the treatments of regulating menstrual flow, inflamed, lowering blood glucose level and diarrhea. This plant sp...

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Main Author:	Sulaiman, Siti Nazira
Format:	Student Project
Language:	English
Published:	Faculty of Applied Sciences, Universiti Teknologi MARA 2017
Subjects:	Physical and theoretical chemistry
Online Access:	http://ir.uitm.edu.my/id/eprint/25916/ http://ir.uitm.edu.my/id/eprint/25916/1/PPb_SITI%20NAZIRA%20SULAIMAN%20AS%20C%2017_5.PDF

id	uitm-25916
recordtype	eprints
spelling	uitm-259162019-11-28T07:20:36Z http://ir.uitm.edu.my/id/eprint/25916/ Chemical constituents from the twig of jasminum sambac and its antioxidant activity / Siti Nazira Sulaiman Sulaiman, Siti Nazira Physical and theoretical chemistry Jasminum sambac or J. sambac is a plant species from family of Oleaceae which widely cultivated throughout Malaysia. The twig, stem, flowers and roots of the plant used traditionally in the treatments of regulating menstrual flow, inflamed, lowering blood glucose level and diarrhea. This plant species was found to contain chemical constituents that have antioxidant properties which could reduce oxidative stress. Oxidative stress is the major role involved in the aetiology of depression. The concentrations of antioxidants and some pro-oxidative enzymes in the human brain may be involved in depression. The objective of this study to determine the chemical constituent from the twig of J. sambac and its antioxidant activity. The twig of J. sambac was extracted using methanol, petroleum ether and dichlorometane solvent. Phytochemical screening of the methanol extract found that the extract was content saponin, tannin and triterpenoid. Result of TLC screening of dichloromethane extract found that the extract contained terpenoid and alkaloid. Radical scavenging activity of extracts was assessed by DPPH free radical scavenging assay. Dichloromethane extract scavenged DPPH radicals more effective compare to methanol and petroleum ether extracts. The percent of radical scavenging activity of dichloromethane was (lC50 = 5.22 ppm) while for the methanol and petroleum ether extract are more than 100 ppm. The isolated compounds from dichloromethane extract that responsible for the antioxidant activity in J. sambac were known as isoamyl nitrite and benzophenone. The plant appears to be a promising source of bioactive compound with antioxidant activity. Faculty of Applied Sciences, Universiti Teknologi MARA 2017 Student Project NonPeerReviewed text en http://ir.uitm.edu.my/id/eprint/25916/1/PPb_SITI%20NAZIRA%20SULAIMAN%20AS%20C%2017_5.PDF Sulaiman, Siti Nazira (2017) Chemical constituents from the twig of jasminum sambac and its antioxidant activity / Siti Nazira Sulaiman. [Student Project] (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Teknologi MARA
building	UiTM Institutional Repository
collection	Online Access
language	English
topic	Physical and theoretical chemistry
spellingShingle	Physical and theoretical chemistry Sulaiman, Siti Nazira Chemical constituents from the twig of jasminum sambac and its antioxidant activity / Siti Nazira Sulaiman
description	Jasminum sambac or J. sambac is a plant species from family of Oleaceae which widely cultivated throughout Malaysia. The twig, stem, flowers and roots of the plant used traditionally in the treatments of regulating menstrual flow, inflamed, lowering blood glucose level and diarrhea. This plant species was found to contain chemical constituents that have antioxidant properties which could reduce oxidative stress. Oxidative stress is the major role involved in the aetiology of depression. The concentrations of antioxidants and some pro-oxidative enzymes in the human brain may be involved in depression. The objective of this study to determine the chemical constituent from the twig of J. sambac and its antioxidant activity. The twig of J. sambac was extracted using methanol, petroleum ether and dichlorometane solvent. Phytochemical screening of the methanol extract found that the extract was content saponin, tannin and triterpenoid. Result of TLC screening of dichloromethane extract found that the extract contained terpenoid and alkaloid. Radical scavenging activity of extracts was assessed by DPPH free radical scavenging assay. Dichloromethane extract scavenged DPPH radicals more effective compare to methanol and petroleum ether extracts. The percent of radical scavenging activity of dichloromethane was (lC50 = 5.22 ppm) while for the methanol and petroleum ether extract are more than 100 ppm. The isolated compounds from dichloromethane extract that responsible for the antioxidant activity in J. sambac were known as isoamyl nitrite and benzophenone. The plant appears to be a promising source of bioactive compound with antioxidant activity.
format	Student Project
author	Sulaiman, Siti Nazira
author_facet	Sulaiman, Siti Nazira
author_sort	Sulaiman, Siti Nazira
title	Chemical constituents from the twig of jasminum sambac and its antioxidant activity / Siti Nazira Sulaiman
title_short	Chemical constituents from the twig of jasminum sambac and its antioxidant activity / Siti Nazira Sulaiman
title_full	Chemical constituents from the twig of jasminum sambac and its antioxidant activity / Siti Nazira Sulaiman
title_fullStr	Chemical constituents from the twig of jasminum sambac and its antioxidant activity / Siti Nazira Sulaiman
title_full_unstemmed	Chemical constituents from the twig of jasminum sambac and its antioxidant activity / Siti Nazira Sulaiman
title_sort	chemical constituents from the twig of jasminum sambac and its antioxidant activity / siti nazira sulaiman
publisher	Faculty of Applied Sciences, Universiti Teknologi MARA
publishDate	2017
url	http://ir.uitm.edu.my/id/eprint/25916/ http://ir.uitm.edu.my/id/eprint/25916/1/PPb_SITI%20NAZIRA%20SULAIMAN%20AS%20C%2017_5.PDF
first_indexed	2023-09-18T23:15:46Z
last_indexed	2023-09-18T23:15:46Z
_version_	1777419101080125440

Chemical constituents from the twig of jasminum sambac and its antioxidant activity / Siti Nazira Sulaiman

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