The influence of tocotrienol on the development of preimplantation embryos, implantation sites and pregnany outcomes in corticosterone-treated mice / Dr Nuraliza Abdul Satar, Professor Dr Mohd Hamim Rajikin and Dr Nor Ashikin Mohamed Noor Khan

The influence of tocotrienol on the development of preimplantation embryos, implantation sites and pregnany outcomes in corticosterone-treated mice / Dr Nuraliza Abdul Satar, Professor Dr Mohd Hamim Rajikin and Dr Nor Ashikin Mohamed Noor Khan

Stress is an attribute of modern life style. Stress is a daily problem encountered by men and women where it affects reproductive system and could influence fertility (Senders & Bruce, 1997; Vilar, 1993). Fertility issues on couples have been widely discussed around the world. It has been estima...

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Main Authors: Abdul Satar, Nuraliza, Rajikin, Mohd Hamim, Mohamed Noor Khan, Nor Ashikin
Format: Research Reports
Language:English
Published: Research Management Institute (RMI) 2011
Subjects:
Examination. Diagnosis
Online Access:http://ir.uitm.edu.my/id/eprint/26407/
http://ir.uitm.edu.my/id/eprint/26407/1/LP_NURALIZA%20ABDUL%20SATAR%2011_5.pdf
id uitm-26407
recordtype eprints
spelling uitm-264072019-11-14T09:16:54Z http://ir.uitm.edu.my/id/eprint/26407/ The influence of tocotrienol on the development of preimplantation embryos, implantation sites and pregnany outcomes in corticosterone-treated mice / Dr Nuraliza Abdul Satar, Professor Dr Mohd Hamim Rajikin and Dr Nor Ashikin Mohamed Noor Khan Abdul Satar, Nuraliza Rajikin, Mohd Hamim Mohamed Noor Khan, Nor Ashikin Examination. Diagnosis Stress is an attribute of modern life style. Stress is a daily problem encountered by men and women where it affects reproductive system and could influence fertility (Senders & Bruce, 1997; Vilar, 1993). Fertility issues on couples have been widely discussed around the world. It has been estimated that in 2002, about 35 to 70 million couples worldwide are infertile and have turned to Assisted Reproductive Technology (ART) to overcome their infertility (Schultz & Williams, 2002). Stress results in enhanced release of glucocorticoid due to activation of sympathoadrenals and hypothalamic-pituitary-adrenal axis. Increased glucocorticoid levels, i.e. cortisol in human and corticosterone (CORT) in rodents are indication of stress (Joels et al., 2007). Several stages of normal reproductive process could be disturbed by stress (Euker & Riegle, 1973). Adrenocortical activation during the preimplantation phase may inhibit fertility in women (Rowel, 1970). “Stress” was defined as teratogenic and CORT is the most probable adrenal steroid hormone involved in mouse under stress condition (Hackman & Brown, 1972). In human, early pregnancy loss is attributed by maternal stress as indicated by increased cortisol levels (Nepomnaschy et al., 2006). Exogenous CORT administration during second term of pregnancy in rodents resulted in an increased frequency of totally resorbed litters, where the effect seen is directly proportional to the dose of CORT administration (Hackman & Brown, 1972). However, the mechanisms that affect the reproductive system in that study remain unclear… Research Management Institute (RMI) 2011 Research Reports NonPeerReviewed text en http://ir.uitm.edu.my/id/eprint/26407/1/LP_NURALIZA%20ABDUL%20SATAR%2011_5.pdf Abdul Satar, Nuraliza and Rajikin, Mohd Hamim and Mohamed Noor Khan, Nor Ashikin (2011) The influence of tocotrienol on the development of preimplantation embryos, implantation sites and pregnany outcomes in corticosterone-treated mice / Dr Nuraliza Abdul Satar, Professor Dr Mohd Hamim Rajikin and Dr Nor Ashikin Mohamed Noor Khan. [Research Reports] (Unpublished)
repository_type Digital Repository
institution_category Local University
institution Universiti Teknologi MARA
building UiTM Institutional Repository
collection Online Access
language English
topic Examination. Diagnosis
spellingShingle Examination. Diagnosis
Abdul Satar, Nuraliza
Rajikin, Mohd Hamim
Mohamed Noor Khan, Nor Ashikin
The influence of tocotrienol on the development of preimplantation embryos, implantation sites and pregnany outcomes in corticosterone-treated mice / Dr Nuraliza Abdul Satar, Professor Dr Mohd Hamim Rajikin and Dr Nor Ashikin Mohamed Noor Khan
description Stress is an attribute of modern life style. Stress is a daily problem encountered by men and women where it affects reproductive system and could influence fertility (Senders & Bruce, 1997; Vilar, 1993). Fertility issues on couples have been widely discussed around the world. It has been estimated that in 2002, about 35 to 70 million couples worldwide are infertile and have turned to Assisted Reproductive Technology (ART) to overcome their infertility (Schultz & Williams, 2002). Stress results in enhanced release of glucocorticoid due to activation of sympathoadrenals and hypothalamic-pituitary-adrenal axis. Increased glucocorticoid levels, i.e. cortisol in human and corticosterone (CORT) in rodents are indication of stress (Joels et al., 2007). Several stages of normal reproductive process could be disturbed by stress (Euker & Riegle, 1973). Adrenocortical activation during the preimplantation phase may inhibit fertility in women (Rowel, 1970). “Stress” was defined as teratogenic and CORT is the most probable adrenal steroid hormone involved in mouse under stress condition (Hackman & Brown, 1972). In human, early pregnancy loss is attributed by maternal stress as indicated by increased cortisol levels (Nepomnaschy et al., 2006). Exogenous CORT administration during second term of pregnancy in rodents resulted in an increased frequency of totally resorbed litters, where the effect seen is directly proportional to the dose of CORT administration (Hackman & Brown, 1972). However, the mechanisms that affect the reproductive system in that study remain unclear…
format Research Reports
author Abdul Satar, Nuraliza
Rajikin, Mohd Hamim
Mohamed Noor Khan, Nor Ashikin
author_facet Abdul Satar, Nuraliza
Rajikin, Mohd Hamim
Mohamed Noor Khan, Nor Ashikin
author_sort Abdul Satar, Nuraliza
title The influence of tocotrienol on the development of preimplantation embryos, implantation sites and pregnany outcomes in corticosterone-treated mice / Dr Nuraliza Abdul Satar, Professor Dr Mohd Hamim Rajikin and Dr Nor Ashikin Mohamed Noor Khan
title_short The influence of tocotrienol on the development of preimplantation embryos, implantation sites and pregnany outcomes in corticosterone-treated mice / Dr Nuraliza Abdul Satar, Professor Dr Mohd Hamim Rajikin and Dr Nor Ashikin Mohamed Noor Khan
title_full The influence of tocotrienol on the development of preimplantation embryos, implantation sites and pregnany outcomes in corticosterone-treated mice / Dr Nuraliza Abdul Satar, Professor Dr Mohd Hamim Rajikin and Dr Nor Ashikin Mohamed Noor Khan
title_fullStr The influence of tocotrienol on the development of preimplantation embryos, implantation sites and pregnany outcomes in corticosterone-treated mice / Dr Nuraliza Abdul Satar, Professor Dr Mohd Hamim Rajikin and Dr Nor Ashikin Mohamed Noor Khan
title_full_unstemmed The influence of tocotrienol on the development of preimplantation embryos, implantation sites and pregnany outcomes in corticosterone-treated mice / Dr Nuraliza Abdul Satar, Professor Dr Mohd Hamim Rajikin and Dr Nor Ashikin Mohamed Noor Khan
title_sort influence of tocotrienol on the development of preimplantation embryos, implantation sites and pregnany outcomes in corticosterone-treated mice / dr nuraliza abdul satar, professor dr mohd hamim rajikin and dr nor ashikin mohamed noor khan
publisher Research Management Institute (RMI)
publishDate 2011
url http://ir.uitm.edu.my/id/eprint/26407/
http://ir.uitm.edu.my/id/eprint/26407/1/LP_NURALIZA%20ABDUL%20SATAR%2011_5.pdf
first_indexed 2023-09-18T23:16:49Z
last_indexed 2023-09-18T23:16:49Z
_version_ 1777419167089033216

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