Determination of bisphenol a in plastic bottles by using high performance liquid chromatography (hplc) / Ain Nur Syafiqah Sariman

Bisphenol A (BP A) is an endocrine disrupters which is mainly used in the plastic industry. On the other words, it means that BPA is able to mimic or interfere with the body's hormones and disrupts the endocrine system. Therefore, it can affected the consumer's health. Thus, in this resear...

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Main Author:	Sariman, Ain Nur Syafiqah
Format:	Student Project
Language:	English
Published:	Faculty of Applied Sciences 2017
Subjects:	QD Chemistry Extraction (Chemistry)
Online Access:	http://ir.uitm.edu.my/id/eprint/26619/ http://ir.uitm.edu.my/id/eprint/26619/1/PPb_AIN%20NUR%20SYAFIQAH%20SARIMAN%20AS%20N%2017_5.pdf

id	uitm-26619
recordtype	eprints
spelling	uitm-266192019-12-10T08:53:51Z http://ir.uitm.edu.my/id/eprint/26619/ Determination of bisphenol a in plastic bottles by using high performance liquid chromatography (hplc) / Ain Nur Syafiqah Sariman Sariman, Ain Nur Syafiqah QD Chemistry Extraction (Chemistry) Bisphenol A (BP A) is an endocrine disrupters which is mainly used in the plastic industry. On the other words, it means that BPA is able to mimic or interfere with the body's hormones and disrupts the endocrine system. Therefore, it can affected the consumer's health. Thus, in this research, BP A was detected by using high performance liquid chromatography (HPLC) which equipped with UV detector and C 18 column as its stationary phase. The mobile phase was composed of 65 % acetonitrile and 35 % deionized water where the flow rate was set to 0.75 mL/min for solid phase extraction (SPE) and 1.0 mL/min for liquid liquid extraction (LLE). Other than that, UV wavelength and column temperature used was 230 nm and 30°C respectively. In this analysis, the detection of BPA by using different types of extraction were studied. SPE and LLE were conducted in order to extract the BPA in the plastic bottles. At the end of this analysis, the analytical method was validated according to various parameter such as calibration curve, limit of detection (LOD), limit of quantification (LOQ) and accuracy. The best linearity obtained was in the range of 0.5 ppm - 30 ppm and 10 ppm - 50 ppm with a good linear correlation coefficient was observed with R2 = 0.9943 and R2 = 0.963 . The value of LOD and LOQ obtained from the calculation was 0.0043 ppm and 0.0146 ppm respectively. From the analysis, it was shown that LLE was the best method that could extract the BPA in the plastic bottles whereas there was no BP A found in the samples by using SPE method. Faculty of Applied Sciences 2017 Student Project NonPeerReviewed text en http://ir.uitm.edu.my/id/eprint/26619/1/PPb_AIN%20NUR%20SYAFIQAH%20SARIMAN%20AS%20N%2017_5.pdf Sariman, Ain Nur Syafiqah (2017) Determination of bisphenol a in plastic bottles by using high performance liquid chromatography (hplc) / Ain Nur Syafiqah Sariman. [Student Project] (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Teknologi MARA
building	UiTM Institutional Repository
collection	Online Access
language	English
topic	QD Chemistry Extraction (Chemistry)
spellingShingle	QD Chemistry Extraction (Chemistry) Sariman, Ain Nur Syafiqah Determination of bisphenol a in plastic bottles by using high performance liquid chromatography (hplc) / Ain Nur Syafiqah Sariman
description	Bisphenol A (BP A) is an endocrine disrupters which is mainly used in the plastic industry. On the other words, it means that BPA is able to mimic or interfere with the body's hormones and disrupts the endocrine system. Therefore, it can affected the consumer's health. Thus, in this research, BP A was detected by using high performance liquid chromatography (HPLC) which equipped with UV detector and C 18 column as its stationary phase. The mobile phase was composed of 65 % acetonitrile and 35 % deionized water where the flow rate was set to 0.75 mL/min for solid phase extraction (SPE) and 1.0 mL/min for liquid liquid extraction (LLE). Other than that, UV wavelength and column temperature used was 230 nm and 30°C respectively. In this analysis, the detection of BPA by using different types of extraction were studied. SPE and LLE were conducted in order to extract the BPA in the plastic bottles. At the end of this analysis, the analytical method was validated according to various parameter such as calibration curve, limit of detection (LOD), limit of quantification (LOQ) and accuracy. The best linearity obtained was in the range of 0.5 ppm - 30 ppm and 10 ppm - 50 ppm with a good linear correlation coefficient was observed with R2 = 0.9943 and R2 = 0.963 . The value of LOD and LOQ obtained from the calculation was 0.0043 ppm and 0.0146 ppm respectively. From the analysis, it was shown that LLE was the best method that could extract the BPA in the plastic bottles whereas there was no BP A found in the samples by using SPE method.
format	Student Project
author	Sariman, Ain Nur Syafiqah
author_facet	Sariman, Ain Nur Syafiqah
author_sort	Sariman, Ain Nur Syafiqah
title	Determination of bisphenol a in plastic bottles by using high performance liquid chromatography (hplc) / Ain Nur Syafiqah Sariman
title_short	Determination of bisphenol a in plastic bottles by using high performance liquid chromatography (hplc) / Ain Nur Syafiqah Sariman
title_full	Determination of bisphenol a in plastic bottles by using high performance liquid chromatography (hplc) / Ain Nur Syafiqah Sariman
title_fullStr	Determination of bisphenol a in plastic bottles by using high performance liquid chromatography (hplc) / Ain Nur Syafiqah Sariman
title_full_unstemmed	Determination of bisphenol a in plastic bottles by using high performance liquid chromatography (hplc) / Ain Nur Syafiqah Sariman
title_sort	determination of bisphenol a in plastic bottles by using high performance liquid chromatography (hplc) / ain nur syafiqah sariman
publisher	Faculty of Applied Sciences
publishDate	2017
url	http://ir.uitm.edu.my/id/eprint/26619/ http://ir.uitm.edu.my/id/eprint/26619/1/PPb_AIN%20NUR%20SYAFIQAH%20SARIMAN%20AS%20N%2017_5.pdf
first_indexed	2023-09-18T23:17:09Z
last_indexed	2023-09-18T23:17:09Z
_version_	1777419188474740736

Determination of bisphenol a in plastic bottles by using high performance liquid chromatography (hplc) / Ain Nur Syafiqah Sariman

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