Evaluation of wound healing activities between melastoma malabathricum leaves extract and chromolaena odorata leaves extract in male sprague dawley rats / Siti Muzaifah Mustapa

Melastoma malabathricum and Chromoalaena odorata are traditional remedies used by Asian, generally to heal the wound. To date, no data on comparison of percentage wound healing between Melastoma malabathricum leaves extract and Chromolaena odorata leaves extract been studied. Current study was desig...

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Main Author:	Mustapa, Siti Muzaifah
Format:	Thesis
Language:	English
Published:	2015
Subjects:	Antioxidants Clinical pathology. Laboratory technique
Online Access:	http://ir.uitm.edu.my/id/eprint/27892/ http://ir.uitm.edu.my/id/eprint/27892/1/TD_SITI%20MUZAIFAH%20MUSTAPA%20HS%2015_5.pdf

id	uitm-27892
recordtype	eprints
spelling	uitm-278922020-01-30T03:47:34Z http://ir.uitm.edu.my/id/eprint/27892/ Evaluation of wound healing activities between melastoma malabathricum leaves extract and chromolaena odorata leaves extract in male sprague dawley rats / Siti Muzaifah Mustapa Mustapa, Siti Muzaifah Antioxidants Clinical pathology. Laboratory technique Melastoma malabathricum and Chromoalaena odorata are traditional remedies used by Asian, generally to heal the wound. To date, no data on comparison of percentage wound healing between Melastoma malabathricum leaves extract and Chromolaena odorata leaves extract been studied. Current study was designed to compare wound healing activities between M.malabathricum leaves extract and C.odorata leaves extract in vivo. Phytochemical analysis for both herbal plants also had been done by using methanol solvent to determine concentration of flavonoid and tannin. Sixteen male Sprague dawley rats used as excisional wound model and wound was created with area 4cm2 on their dorsal by using scalpel after acclimatized for two weeks. They were divided to four groups whereby each group was gave different treatment that were group I: gentamicin cream, group II: 10% Melastoma malabathricum ointment, group III: 10% Chromolaena odorata ointment and group IV: Vaseline and in three days interval until fifteenth day percentage of wound area was measured and calculated. M. malabathricum leaves extract consist higher concentration of flavonoids and tannins compare to the C. odorata leaves extract and visually, M. malabathricum leaves extract accelerate wound healing faster than C. ododrata leaves extract, as the concentration of flavonoids and tannins were high. Statistically the result was not significant. In conclusion, M. malabathricum leaves extract and C. odorata leaves extract do show potential asset that can be used for development of alternative remedy. 2015 Thesis NonPeerReviewed text en http://ir.uitm.edu.my/id/eprint/27892/1/TD_SITI%20MUZAIFAH%20MUSTAPA%20HS%2015_5.pdf Mustapa, Siti Muzaifah (2015) Evaluation of wound healing activities between melastoma malabathricum leaves extract and chromolaena odorata leaves extract in male sprague dawley rats / Siti Muzaifah Mustapa. Degree thesis, Universiti Teknologi MARA.
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Teknologi MARA
building	UiTM Institutional Repository
collection	Online Access
language	English
topic	Antioxidants Clinical pathology. Laboratory technique
spellingShingle	Antioxidants Clinical pathology. Laboratory technique Mustapa, Siti Muzaifah Evaluation of wound healing activities between melastoma malabathricum leaves extract and chromolaena odorata leaves extract in male sprague dawley rats / Siti Muzaifah Mustapa
description	Melastoma malabathricum and Chromoalaena odorata are traditional remedies used by Asian, generally to heal the wound. To date, no data on comparison of percentage wound healing between Melastoma malabathricum leaves extract and Chromolaena odorata leaves extract been studied. Current study was designed to compare wound healing activities between M.malabathricum leaves extract and C.odorata leaves extract in vivo. Phytochemical analysis for both herbal plants also had been done by using methanol solvent to determine concentration of flavonoid and tannin. Sixteen male Sprague dawley rats used as excisional wound model and wound was created with area 4cm2 on their dorsal by using scalpel after acclimatized for two weeks. They were divided to four groups whereby each group was gave different treatment that were group I: gentamicin cream, group II: 10% Melastoma malabathricum ointment, group III: 10% Chromolaena odorata ointment and group IV: Vaseline and in three days interval until fifteenth day percentage of wound area was measured and calculated. M. malabathricum leaves extract consist higher concentration of flavonoids and tannins compare to the C. odorata leaves extract and visually, M. malabathricum leaves extract accelerate wound healing faster than C. ododrata leaves extract, as the concentration of flavonoids and tannins were high. Statistically the result was not significant. In conclusion, M. malabathricum leaves extract and C. odorata leaves extract do show potential asset that can be used for development of alternative remedy.
format	Thesis
author	Mustapa, Siti Muzaifah
author_facet	Mustapa, Siti Muzaifah
author_sort	Mustapa, Siti Muzaifah
title	Evaluation of wound healing activities between melastoma malabathricum leaves extract and chromolaena odorata leaves extract in male sprague dawley rats / Siti Muzaifah Mustapa
title_short	Evaluation of wound healing activities between melastoma malabathricum leaves extract and chromolaena odorata leaves extract in male sprague dawley rats / Siti Muzaifah Mustapa
title_full	Evaluation of wound healing activities between melastoma malabathricum leaves extract and chromolaena odorata leaves extract in male sprague dawley rats / Siti Muzaifah Mustapa
title_fullStr	Evaluation of wound healing activities between melastoma malabathricum leaves extract and chromolaena odorata leaves extract in male sprague dawley rats / Siti Muzaifah Mustapa
title_full_unstemmed	Evaluation of wound healing activities between melastoma malabathricum leaves extract and chromolaena odorata leaves extract in male sprague dawley rats / Siti Muzaifah Mustapa
title_sort	evaluation of wound healing activities between melastoma malabathricum leaves extract and chromolaena odorata leaves extract in male sprague dawley rats / siti muzaifah mustapa
publishDate	2015
url	http://ir.uitm.edu.my/id/eprint/27892/ http://ir.uitm.edu.my/id/eprint/27892/1/TD_SITI%20MUZAIFAH%20MUSTAPA%20HS%2015_5.pdf
first_indexed	2023-09-18T23:19:12Z
last_indexed	2023-09-18T23:19:12Z
_version_	1777419316997652480

Evaluation of wound healing activities between melastoma malabathricum leaves extract and chromolaena odorata leaves extract in male sprague dawley rats / Siti Muzaifah Mustapa

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