Preliminary screening on the effect of persicaria minor (kesum) against haemonchus contortus / Nik Noor Haszwani Yahya

Haemonchus contortus is a type of nematode that is commonly infecting the sheep which causes hemorrhagic anemia or even death towards sheep. This gastrointestinal parasite could also develop resistance towards synthetic antihelminthics, leads to the study in finding the alternative antihelminthics....

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Main Author:	Yahya, Nik Noor Haszwani
Format:	Student Project
Language:	English
Published:	Faculty of Applied Sciences 2017
Subjects:	Extraction (Chemistry) QR Microbiology
Online Access:	http://ir.uitm.edu.my/id/eprint/28479/ http://ir.uitm.edu.my/id/eprint/28479/1/PPb_NIK%20NOOR%20HASZWANI%20YAHYA%20AS%20N%2017_5.pdf

id	uitm-28479
recordtype	eprints
spelling	uitm-284792020-03-09T08:01:49Z http://ir.uitm.edu.my/id/eprint/28479/ Preliminary screening on the effect of persicaria minor (kesum) against haemonchus contortus / Nik Noor Haszwani Yahya Yahya, Nik Noor Haszwani Extraction (Chemistry) QR Microbiology Haemonchus contortus is a type of nematode that is commonly infecting the sheep which causes hemorrhagic anemia or even death towards sheep. This gastrointestinal parasite could also develop resistance towards synthetic antihelminthics, leads to the study in finding the alternative antihelminthics. So, the antihelminthic activity of Kesum against H. contortus was investigated. Kesum plant was dried and soaked in ethanol to obtain the ethanolic Kesum extract. The phytochemical assays (tannins, steroids, flavonoids, alkaloids and saponins) were done towards the extract. Preliminary screening by using egg hatch assays (EHA) and larval development assays (LDA) were done in triplicate form with different extracts concentrations (50, 25, 12.5, 6.25, 3.125 mg/mL) to study the efficacy inhibition percentage of the egg and larval development of H. contortus by Kesum ethanolic extract. 0.125 mg/mL of Albendazole used as positive control and 1 % DMSO and 95% ethanol as negative control. Kesum ethanolic extracts shows presence of all the phytochemical contents. During the experiment low number of eggs and larvae obtained, which does not fall in the range of 100 eggs/0.2 mL egg suspensions. In spite of that, Kesum extracts were clearly identified to exhibit larvicidal properties against H. contortus as observed in LDA. Thus, it can be stated that Kesum has the possibility to inhibiting the development of H. contortus. Further study towards the antihelminthic activity of Kesum against H. contortus should be done and followed by the identification of phytochemicals in Kesum that affects the development of H. contortus. Faculty of Applied Sciences 2017 Student Project NonPeerReviewed text en http://ir.uitm.edu.my/id/eprint/28479/1/PPb_NIK%20NOOR%20HASZWANI%20YAHYA%20AS%20N%2017_5.pdf Yahya, Nik Noor Haszwani (2017) Preliminary screening on the effect of persicaria minor (kesum) against haemonchus contortus / Nik Noor Haszwani Yahya. [Student Project] (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Teknologi MARA
building	UiTM Institutional Repository
collection	Online Access
language	English
topic	Extraction (Chemistry) QR Microbiology
spellingShingle	Extraction (Chemistry) QR Microbiology Yahya, Nik Noor Haszwani Preliminary screening on the effect of persicaria minor (kesum) against haemonchus contortus / Nik Noor Haszwani Yahya
description	Haemonchus contortus is a type of nematode that is commonly infecting the sheep which causes hemorrhagic anemia or even death towards sheep. This gastrointestinal parasite could also develop resistance towards synthetic antihelminthics, leads to the study in finding the alternative antihelminthics. So, the antihelminthic activity of Kesum against H. contortus was investigated. Kesum plant was dried and soaked in ethanol to obtain the ethanolic Kesum extract. The phytochemical assays (tannins, steroids, flavonoids, alkaloids and saponins) were done towards the extract. Preliminary screening by using egg hatch assays (EHA) and larval development assays (LDA) were done in triplicate form with different extracts concentrations (50, 25, 12.5, 6.25, 3.125 mg/mL) to study the efficacy inhibition percentage of the egg and larval development of H. contortus by Kesum ethanolic extract. 0.125 mg/mL of Albendazole used as positive control and 1 % DMSO and 95% ethanol as negative control. Kesum ethanolic extracts shows presence of all the phytochemical contents. During the experiment low number of eggs and larvae obtained, which does not fall in the range of 100 eggs/0.2 mL egg suspensions. In spite of that, Kesum extracts were clearly identified to exhibit larvicidal properties against H. contortus as observed in LDA. Thus, it can be stated that Kesum has the possibility to inhibiting the development of H. contortus. Further study towards the antihelminthic activity of Kesum against H. contortus should be done and followed by the identification of phytochemicals in Kesum that affects the development of H. contortus.
format	Student Project
author	Yahya, Nik Noor Haszwani
author_facet	Yahya, Nik Noor Haszwani
author_sort	Yahya, Nik Noor Haszwani
title	Preliminary screening on the effect of persicaria minor (kesum) against haemonchus contortus / Nik Noor Haszwani Yahya
title_short	Preliminary screening on the effect of persicaria minor (kesum) against haemonchus contortus / Nik Noor Haszwani Yahya
title_full	Preliminary screening on the effect of persicaria minor (kesum) against haemonchus contortus / Nik Noor Haszwani Yahya
title_fullStr	Preliminary screening on the effect of persicaria minor (kesum) against haemonchus contortus / Nik Noor Haszwani Yahya
title_full_unstemmed	Preliminary screening on the effect of persicaria minor (kesum) against haemonchus contortus / Nik Noor Haszwani Yahya
title_sort	preliminary screening on the effect of persicaria minor (kesum) against haemonchus contortus / nik noor haszwani yahya
publisher	Faculty of Applied Sciences
publishDate	2017
url	http://ir.uitm.edu.my/id/eprint/28479/ http://ir.uitm.edu.my/id/eprint/28479/1/PPb_NIK%20NOOR%20HASZWANI%20YAHYA%20AS%20N%2017_5.pdf
first_indexed	2023-09-18T23:20:20Z
last_indexed	2023-09-18T23:20:20Z
_version_	1777419388968763392

Preliminary screening on the effect of persicaria minor (kesum) against haemonchus contortus / Nik Noor Haszwani Yahya

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