Biological activity studies of some rubiaceous plants (subfamily rubioideae) and phytochemical investigation of hedyotis philippinensis / Emi Norzehan Mohamad Mahbob

In this study, the biological activities of 13 Rubioideae plants were investigated with the aim of iscovering its bioactive constituents. The assays employed were ferric thiocyanate (FTC), thiobarbituric acid (TBA) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) methods for antioxidant potential as well as...

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Main Author:	Mohamad Mahbob, Emi Norzehan
Format:	Thesis
Language:	English
Published:	2010
Subjects:	Bioactive compounds Rubiaceae (Madder). Morinda citrifolia
Online Access:	http://ir.uitm.edu.my/id/eprint/4834/ http://ir.uitm.edu.my/id/eprint/4834/1/TM_EMI%20NORZEHAN%20MOHAMAD%20MAHBOB%20AS%2010_5.pdf

id	uitm-4834
recordtype	eprints
spelling	uitm-48342018-08-30T03:51:04Z http://ir.uitm.edu.my/id/eprint/4834/ Biological activity studies of some rubiaceous plants (subfamily rubioideae) and phytochemical investigation of hedyotis philippinensis / Emi Norzehan Mohamad Mahbob Mohamad Mahbob, Emi Norzehan Bioactive compounds Rubiaceae (Madder). Morinda citrifolia In this study, the biological activities of 13 Rubioideae plants were investigated with the aim of iscovering its bioactive constituents. The assays employed were ferric thiocyanate (FTC), thiobarbituric acid (TBA) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) methods for antioxidant potential as well as Griess assay for the measurement of nitric oxide (NO) inhibition in lipopolysaccharide (LPS) and interferon-y (IFN-y)-treated RAW 264.7 cells. In the in vitro antioxidant assays including FTC, TBA and DPPH, all the tested plants exert strong antioxidant potential. Hedyotis philippinensis (leaves and stems), Spermacoce exilis and Spermacoce latifolia showed potent inhibitory activity on NO production in LPS and IFN-y-induced RAW 264.7 cells in the anti-inflammatory assay. For the second part of this study, phytochemical investigation of the leaves and stems of selected Hedyotis species, namely H. philippinensis was carried out using various chromatographic and solid phase extraction techniques to yield the major iridoid glycoside, asperuloside along with scopoletin and astragalin. 2010 Thesis NonPeerReviewed text en http://ir.uitm.edu.my/id/eprint/4834/1/TM_EMI%20NORZEHAN%20MOHAMAD%20MAHBOB%20AS%2010_5.pdf Mohamad Mahbob, Emi Norzehan (2010) Biological activity studies of some rubiaceous plants (subfamily rubioideae) and phytochemical investigation of hedyotis philippinensis / Emi Norzehan Mohamad Mahbob. Masters thesis, Universiti Teknologi MARA.
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Teknologi MARA
building	UiTM Institutional Repository
collection	Online Access
language	English
topic	Bioactive compounds Rubiaceae (Madder). Morinda citrifolia
spellingShingle	Bioactive compounds Rubiaceae (Madder). Morinda citrifolia Mohamad Mahbob, Emi Norzehan Biological activity studies of some rubiaceous plants (subfamily rubioideae) and phytochemical investigation of hedyotis philippinensis / Emi Norzehan Mohamad Mahbob
description	In this study, the biological activities of 13 Rubioideae plants were investigated with the aim of iscovering its bioactive constituents. The assays employed were ferric thiocyanate (FTC), thiobarbituric acid (TBA) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) methods for antioxidant potential as well as Griess assay for the measurement of nitric oxide (NO) inhibition in lipopolysaccharide (LPS) and interferon-y (IFN-y)-treated RAW 264.7 cells. In the in vitro antioxidant assays including FTC, TBA and DPPH, all the tested plants exert strong antioxidant potential. Hedyotis philippinensis (leaves and stems), Spermacoce exilis and Spermacoce latifolia showed potent inhibitory activity on NO production in LPS and IFN-y-induced RAW 264.7 cells in the anti-inflammatory assay. For the second part of this study, phytochemical investigation of the leaves and stems of selected Hedyotis species, namely H. philippinensis was carried out using various chromatographic and solid phase extraction techniques to yield the major iridoid glycoside, asperuloside along with scopoletin and astragalin.
format	Thesis
author	Mohamad Mahbob, Emi Norzehan
author_facet	Mohamad Mahbob, Emi Norzehan
author_sort	Mohamad Mahbob, Emi Norzehan
title	Biological activity studies of some rubiaceous plants (subfamily rubioideae) and phytochemical investigation of hedyotis philippinensis / Emi Norzehan Mohamad Mahbob
title_short	Biological activity studies of some rubiaceous plants (subfamily rubioideae) and phytochemical investigation of hedyotis philippinensis / Emi Norzehan Mohamad Mahbob
title_full	Biological activity studies of some rubiaceous plants (subfamily rubioideae) and phytochemical investigation of hedyotis philippinensis / Emi Norzehan Mohamad Mahbob
title_fullStr	Biological activity studies of some rubiaceous plants (subfamily rubioideae) and phytochemical investigation of hedyotis philippinensis / Emi Norzehan Mohamad Mahbob
title_full_unstemmed	Biological activity studies of some rubiaceous plants (subfamily rubioideae) and phytochemical investigation of hedyotis philippinensis / Emi Norzehan Mohamad Mahbob
title_sort	biological activity studies of some rubiaceous plants (subfamily rubioideae) and phytochemical investigation of hedyotis philippinensis / emi norzehan mohamad mahbob
publishDate	2010
url	http://ir.uitm.edu.my/id/eprint/4834/ http://ir.uitm.edu.my/id/eprint/4834/1/TM_EMI%20NORZEHAN%20MOHAMAD%20MAHBOB%20AS%2010_5.pdf
first_indexed	2023-09-18T22:46:59Z
last_indexed	2023-09-18T22:46:59Z
_version_	1777417290568957952

Biological activity studies of some rubiaceous plants (subfamily rubioideae) and phytochemical investigation of hedyotis philippinensis / Emi Norzehan Mohamad Mahbob

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