An orbital solitary fibrous tumor: report of two cases with different presentation

Solitary fibrous tumour (SFT) is a rare spindle-cell neoplasm that can occur in the orbit. We report two cases of orbital SFT in a 35-year-old female and a 28-year-old male with different presentations. First patient presented with slowly progressive left lateral upper lid mass which is firm in cons...

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Main Authors:	Hanisah AH, Othmaliza Othman, Rona Asnida Nasaruddin, Sunder R, Hazlita Mohd Isa
Format:	Article
Language:	English
Published:	Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre 2016
Online Access:	http://journalarticle.ukm.my/10237/ http://journalarticle.ukm.my/10237/ http://journalarticle.ukm.my/10237/1/4._hanisah_et_al..pdf

id	ukm-10237
recordtype	eprints
spelling	ukm-102372017-03-29T08:48:54Z http://journalarticle.ukm.my/10237/ An orbital solitary fibrous tumor: report of two cases with different presentation Hanisah AH, Othmaliza Othman, Rona Asnida Nasaruddin, Sunder R, Hazlita Mohd Isa, Solitary fibrous tumour (SFT) is a rare spindle-cell neoplasm that can occur in the orbit. We report two cases of orbital SFT in a 35-year-old female and a 28-year-old male with different presentations. First patient presented with slowly progressive left lateral upper lid mass which is firm in consistency and non tender. Patient had non axial proptosis as the mass compressed the globe inferonasally. There was also funduscopy evidence of choroidal folds superotemporally. There is slight impairment of vision on the left eye comparing to right eye. Meanwhile, the second patient presented with a painless diffuse swelling of left upper eyelid. It was soft in consistency, non fluctuate and no opening or pus discharge noted. There is mild mechanical ptosis, however there was no proptosis and no evidence of compression into the globe nor visual impairment.Computed tomography (CT) imaging revealed a well circumscribed and contrast enhanced soft tissue mass intraorbital extraconal mass in both cases. However in the first case, the tumour was at the level of lacrimal gland with compression of the globe, while in second case, it was superior and posterior to the left lacrimal gland with no globe compression. Both patients underwent complete resection of their tumors. The histological findings showed alternating hypercellular and hypocellular areas composed of bland spindle cells with a fibrous stroma. The strong immunoreactivity for CD34 supported the diagnosis of orbital SFT. There was no recurrence at the 2nd and 3rd year follow-up visits for both patients. SFT should be considered as one of the differential diagnosis of an orbital tumor. The combination of CT scan, histologic findings and immunohistochemical staining provide accurate diagnosis. En bloc excision of the tumour is the mainstay of treatment. Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre 2016 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/10237/1/4._hanisah_et_al..pdf Hanisah AH, and Othmaliza Othman, and Rona Asnida Nasaruddin, and Sunder R, and Hazlita Mohd Isa, (2016) An orbital solitary fibrous tumor: report of two cases with different presentation. Journal of Surgical Academia, 6 (2). pp. 18-21. ISSN 2231-7481 http://jsurgacad.com/toc
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	Solitary fibrous tumour (SFT) is a rare spindle-cell neoplasm that can occur in the orbit. We report two cases of orbital SFT in a 35-year-old female and a 28-year-old male with different presentations. First patient presented with slowly progressive left lateral upper lid mass which is firm in consistency and non tender. Patient had non axial proptosis as the mass compressed the globe inferonasally. There was also funduscopy evidence of choroidal folds superotemporally. There is slight impairment of vision on the left eye comparing to right eye. Meanwhile, the second patient presented with a painless diffuse swelling of left upper eyelid. It was soft in consistency, non fluctuate and no opening or pus discharge noted. There is mild mechanical ptosis, however there was no proptosis and no evidence of compression into the globe nor visual impairment.Computed tomography (CT) imaging revealed a well circumscribed and contrast enhanced soft tissue mass intraorbital extraconal mass in both cases. However in the first case, the tumour was at the level of lacrimal gland with compression of the globe, while in second case, it was superior and posterior to the left lacrimal gland with no globe compression. Both patients underwent complete resection of their tumors. The histological findings showed alternating hypercellular and hypocellular areas composed of bland spindle cells with a fibrous stroma. The strong immunoreactivity for CD34 supported the diagnosis of orbital SFT. There was no recurrence at the 2nd and 3rd year follow-up visits for both patients. SFT should be considered as one of the differential diagnosis of an orbital tumor. The combination of CT scan, histologic findings and immunohistochemical staining provide accurate diagnosis. En bloc excision of the tumour is the mainstay of treatment.
format	Article
author	Hanisah AH, Othmaliza Othman, Rona Asnida Nasaruddin, Sunder R, Hazlita Mohd Isa,
spellingShingle	Hanisah AH, Othmaliza Othman, Rona Asnida Nasaruddin, Sunder R, Hazlita Mohd Isa, An orbital solitary fibrous tumor: report of two cases with different presentation
author_facet	Hanisah AH, Othmaliza Othman, Rona Asnida Nasaruddin, Sunder R, Hazlita Mohd Isa,
author_sort	Hanisah AH,
title	An orbital solitary fibrous tumor: report of two cases with different presentation
title_short	An orbital solitary fibrous tumor: report of two cases with different presentation
title_full	An orbital solitary fibrous tumor: report of two cases with different presentation
title_fullStr	An orbital solitary fibrous tumor: report of two cases with different presentation
title_full_unstemmed	An orbital solitary fibrous tumor: report of two cases with different presentation
title_sort	orbital solitary fibrous tumor: report of two cases with different presentation
publisher	Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre
publishDate	2016
url	http://journalarticle.ukm.my/10237/ http://journalarticle.ukm.my/10237/ http://journalarticle.ukm.my/10237/1/4._hanisah_et_al..pdf
first_indexed	2023-09-18T19:56:51Z
last_indexed	2023-09-18T19:56:51Z
_version_	1777406587082637312

An orbital solitary fibrous tumor: report of two cases with different presentation

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