Comparative study on membrane solubilisation of biosynthesized nano-silver & biosynthesized nano-zinc oxide on selected sperm parameter
Extensive applications of nanoparticles are used in the field of catalysis, biosensing, imaging, drug delivery, nano-device fabrication and medicine. Previously, biosynthesized nano-silver and biosynthesized nano-zinc oxide has shown significant effect as antimicrobial agents, thus reduces concern...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Penerbit Universiti Kebangsaan Malaysia
2015
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| Online Access: | http://journalarticle.ukm.my/10345/ http://journalarticle.ukm.my/10345/ http://journalarticle.ukm.my/10345/1/44_1_11.pdf |
| Summary: | Extensive applications of nanoparticles are used in the field of catalysis, biosensing, imaging, drug delivery, nano-device
fabrication and medicine. Previously, biosynthesized nano-silver and biosynthesized nano-zinc oxide has shown significant
effect as antimicrobial agents, thus reduces concern over the threat of antibiotic resistance. Biosynthesis of nano-silver and
nano-zinc oxide using Pandanus amaryllifolius leaf extract and their spermicidal effect was explored in the present research
following characterization using FESEM-EDX and were determined to be spherical in shape and aggregated into regular
structure with high uniformity. The sperm membrane solubilisation property displayed by both biosynthesized nano-silver
and biosynthesized nano-zinc oxide exceeded the effects of 1% (w/v) Triton-X and was most significant at the concentration
of 100 μg/ml. The results suggested that biosynthesized nano-silver and biosynthesized nano-zinc oxide holds possibility as
new generation spermicidal agents. |
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