The effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects

Physical training is associated with axidative stress and improvement in blood antioxidant status. In this study, we investigated the effects of training on plasma malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE) as markers of lipid peroxidation, superoxide dismutase (SOD) activity, and ascorbic a...

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Main Authors:	Farah Fauzi, Siti Balkis Budin, Shahrul Azwan, Leong, Kok Yuen
Format:	Article
Language:	English
Published:	penerbit ukm 2007
Online Access:	http://journalarticle.ukm.my/1092/ http://journalarticle.ukm.my/1092/ http://journalarticle.ukm.my/1092/1/jurnal72.pdf

id	ukm-1092
recordtype	eprints
spelling	ukm-10922016-12-14T06:28:47Z http://journalarticle.ukm.my/1092/ The effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects Farah Fauzi, Siti Balkis Budin, Shahrul Azwan, Leong, Kok Yuen Physical training is associated with axidative stress and improvement in blood antioxidant status. In this study, we investigated the effects of training on plasma malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE) as markers of lipid peroxidation, superoxide dismutase (SOD) activity, and ascorbic acid (AA) after a single bout of acute exercise. Twelve healthy, untrained young adult men were recruited for 5 weeks of aerobic training period. They were subjected to a rope-skipping exercise for 20 minutes at the intensity of 65 – 80% of heart rate reserve, thrice weekly. They also had to perform a single, acute bout of the same exercise protocol prior to and after training period. Venous blood samples were collected at resting condition (BL), immediately (0 h) and 24 hours (24 h) post acute exercise on both single bout sessions. Results showed that the pattern changes of oxidative stress response are quite similar on both acute sessions. The acute bouts of rope-skipping is associated with a significant increased (p= 0.001) in lipid peroxidation markers immediately after cessation of exercise, with a concomitant increase in antioxidant levels, albeit higher when compared to pre-training values (p = 0.001). These changes were followed by a significant decreased (p = 0.001) in all parameters, toward resting values, 24 hours thereafter. The training program seemed to induce a significant increase in MDA and 4-HNE but also enhanced the antioxidant defense system namely SOD and AA among the untrained subjects. penerbit ukm 2007 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/1092/1/jurnal72.pdf Farah Fauzi, and Siti Balkis Budin, and Shahrul Azwan, and Leong, Kok Yuen (2007) The effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects. Jurnal Sains Kesihatan Malaysia, 5 (2). pp. 39-52. ISSN 1675-8161 http://www.fskb.ukm.my/fskbold
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	Physical training is associated with axidative stress and improvement in blood antioxidant status. In this study, we investigated the effects of training on plasma malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE) as markers of lipid peroxidation, superoxide dismutase (SOD) activity, and ascorbic acid (AA) after a single bout of acute exercise. Twelve healthy, untrained young adult men were recruited for 5 weeks of aerobic training period. They were subjected to a rope-skipping exercise for 20 minutes at the intensity of 65 – 80% of heart rate reserve, thrice weekly. They also had to perform a single, acute bout of the same exercise protocol prior to and after training period. Venous blood samples were collected at resting condition (BL), immediately (0 h) and 24 hours (24 h) post acute exercise on both single bout sessions. Results showed that the pattern changes of oxidative stress response are quite similar on both acute sessions. The acute bouts of rope-skipping is associated with a significant increased (p= 0.001) in lipid peroxidation markers immediately after cessation of exercise, with a concomitant increase in antioxidant levels, albeit higher when compared to pre-training values (p = 0.001). These changes were followed by a significant decreased (p = 0.001) in all parameters, toward resting values, 24 hours thereafter. The training program seemed to induce a significant increase in MDA and 4-HNE but also enhanced the antioxidant defense system namely SOD and AA among the untrained subjects.
format	Article
author	Farah Fauzi, Siti Balkis Budin, Shahrul Azwan, Leong, Kok Yuen
spellingShingle	Farah Fauzi, Siti Balkis Budin, Shahrul Azwan, Leong, Kok Yuen The effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects
author_facet	Farah Fauzi, Siti Balkis Budin, Shahrul Azwan, Leong, Kok Yuen
author_sort	Farah Fauzi,
title	The effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects
title_short	The effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects
title_full	The effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects
title_fullStr	The effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects
title_full_unstemmed	The effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects
title_sort	effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects
publisher	penerbit ukm
publishDate	2007
url	http://journalarticle.ukm.my/1092/ http://journalarticle.ukm.my/1092/ http://journalarticle.ukm.my/1092/1/jurnal72.pdf
first_indexed	2023-09-18T19:32:20Z
last_indexed	2023-09-18T19:32:20Z
_version_	1777405044164919296

The effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects

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