Survival study and prognostic factors of ovarian cancer registered in a teaching hospital in Malaysia

Ovarian cancer is one of the highest causes of death among female population in Malaysia. A retrospective cohort study among 127 ovarian cancer patients registered in one of the teaching hospital in Malaysia was conducted from 1st January 2002 until 31st December 2011. The objective of this study wa...

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Main Authors:	Najihah Lokman, Siti Azrin Ab. Hamid, Norsa’adah Bachok
Format:	Article
Language:	English
Published:	Penerbit Universiti Kebangsaan Malaysia 2017
Online Access:	http://journalarticle.ukm.my/11032/ http://journalarticle.ukm.my/11032/ http://journalarticle.ukm.my/11032/1/07%20Najihah%20Lokman.pdf

id	ukm-11032
recordtype	eprints
spelling	ukm-110322017-11-27T12:04:38Z http://journalarticle.ukm.my/11032/ Survival study and prognostic factors of ovarian cancer registered in a teaching hospital in Malaysia Najihah Lokman, Siti Azrin Ab. Hamid, Norsa’adah Bachok, Ovarian cancer is one of the highest causes of death among female population in Malaysia. A retrospective cohort study among 127 ovarian cancer patients registered in one of the teaching hospital in Malaysia was conducted from 1st January 2002 until 31st December 2011. The objective of this study was to determine the median survival time, five year survival probability and prognostic factors of ovarian cancer patients. Only ovarian cancer patients were selected with strict inclusion and exclusion criteria. Data was analyzed using Kaplan-Meier Survival analysis and Cox proportional hazard regression analysis. The results showed that the overall five-year survival probability of ovarian cancer was 35.2% (95%CI: 26.3, 44.3) with 38 month (95%CI: 25.7, 50.1) median survival time. After adjustment for potential cofounder, significant prognostic factors of ovarian cancer were observed in FIGO stage (HR: 2.53; 1.44, 4.45), loss of appetite (HR: 1.95; 1.23, 3.11) and presence of pleural effusion (HR: 1.98; 1.19, 3.30). Overall, the survival probabilities of ovarian cancer were low and further actions must be taken to improve the survival among advanced cancer patients Penerbit Universiti Kebangsaan Malaysia 2017-04 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/11032/1/07%20Najihah%20Lokman.pdf Najihah Lokman, and Siti Azrin Ab. Hamid, and Norsa’adah Bachok, (2017) Survival study and prognostic factors of ovarian cancer registered in a teaching hospital in Malaysia. Sains Malaysiana, 46 (4). pp. 559-565. ISSN 0126-6039 http://www.ukm.my/jsm/english_journals/vol46num4_2017/contentsVol46num4_2017.html
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	Ovarian cancer is one of the highest causes of death among female population in Malaysia. A retrospective cohort study among 127 ovarian cancer patients registered in one of the teaching hospital in Malaysia was conducted from 1st January 2002 until 31st December 2011. The objective of this study was to determine the median survival time, five year survival probability and prognostic factors of ovarian cancer patients. Only ovarian cancer patients were selected with strict inclusion and exclusion criteria. Data was analyzed using Kaplan-Meier Survival analysis and Cox proportional hazard regression analysis. The results showed that the overall five-year survival probability of ovarian cancer was 35.2% (95%CI: 26.3, 44.3) with 38 month (95%CI: 25.7, 50.1) median survival time. After adjustment for potential cofounder, significant prognostic factors of ovarian cancer were observed in FIGO stage (HR: 2.53; 1.44, 4.45), loss of appetite (HR: 1.95; 1.23, 3.11) and presence of pleural effusion (HR: 1.98; 1.19, 3.30). Overall, the survival probabilities of ovarian cancer were low and further actions must be taken to improve the survival among advanced cancer patients
format	Article
author	Najihah Lokman, Siti Azrin Ab. Hamid, Norsa’adah Bachok,
spellingShingle	Najihah Lokman, Siti Azrin Ab. Hamid, Norsa’adah Bachok, Survival study and prognostic factors of ovarian cancer registered in a teaching hospital in Malaysia
author_facet	Najihah Lokman, Siti Azrin Ab. Hamid, Norsa’adah Bachok,
author_sort	Najihah Lokman,
title	Survival study and prognostic factors of ovarian cancer registered in a teaching hospital in Malaysia
title_short	Survival study and prognostic factors of ovarian cancer registered in a teaching hospital in Malaysia
title_full	Survival study and prognostic factors of ovarian cancer registered in a teaching hospital in Malaysia
title_fullStr	Survival study and prognostic factors of ovarian cancer registered in a teaching hospital in Malaysia
title_full_unstemmed	Survival study and prognostic factors of ovarian cancer registered in a teaching hospital in Malaysia
title_sort	survival study and prognostic factors of ovarian cancer registered in a teaching hospital in malaysia
publisher	Penerbit Universiti Kebangsaan Malaysia
publishDate	2017
url	http://journalarticle.ukm.my/11032/ http://journalarticle.ukm.my/11032/ http://journalarticle.ukm.my/11032/1/07%20Najihah%20Lokman.pdf
first_indexed	2023-09-18T19:59:08Z
last_indexed	2023-09-18T19:59:08Z
_version_	1777406730782638080

Survival study and prognostic factors of ovarian cancer registered in a teaching hospital in Malaysia

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