Development of DiabecineTM tablet and confirmation of its physical properties and pharmaceutical safety analysis

Herbal medicine is usually made using dry powdered herbs in the form of capsule. Capsule form herbal supplement suffers lower shelf life as compared to compact herbal powder in tablet form. In this study, Diabecine™, a blend of herbal medicine traditionally used as herbal supplement for diabetic pat...

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Main Authors:	Chee, Teh Liam, Fadzilah Adibah Abdul Majid, Mohd Cairul Iqbal
Format:	Article
Language:	English
Published:	Penerbit Universiti Kebangsaan Malaysia 2017
Online Access:	http://journalarticle.ukm.my/11037/ http://journalarticle.ukm.my/11037/ http://journalarticle.ukm.my/11037/1/12%20Teh%20Liam%20Chee.pdf

id	ukm-11037
recordtype	eprints
spelling	ukm-110372017-11-27T15:53:12Z http://journalarticle.ukm.my/11037/ Development of DiabecineTM tablet and confirmation of its physical properties and pharmaceutical safety analysis Chee, Teh Liam Fadzilah Adibah Abdul Majid, Mohd Cairul Iqbal, Herbal medicine is usually made using dry powdered herbs in the form of capsule. Capsule form herbal supplement suffers lower shelf life as compared to compact herbal powder in tablet form. In this study, Diabecine™, a blend of herbal medicine traditionally used as herbal supplement for diabetic patients was selected and transformed into a compressed tablet. Direct compression method and minimal usage of excipients were the aims of this study. By using direct compression, the blend of 40% fine powder herbs and 60% of excipients performed the best and fulfill the pharmaceutical standard. The safety data of microbial and heavy metal testing obtained met the safety requirements for herbal supplement category under the National Pharmaceutical Control Bureau of Malaysia. In conclusion, the tablet formulation of DiabecineTM is suitable to be manufactured by using direct compression method. This research implicates the possibility of producing tablets with high dose of herbal powder by direct compression method. Penerbit Universiti Kebangsaan Malaysia 2017-04 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/11037/1/12%20Teh%20Liam%20Chee.pdf Chee, Teh Liam and Fadzilah Adibah Abdul Majid, and Mohd Cairul Iqbal, (2017) Development of DiabecineTM tablet and confirmation of its physical properties and pharmaceutical safety analysis. Sains Malaysiana, 46 (4). pp. 597-604. ISSN 0126-6039 http://www.ukm.my/jsm/english_journals/vol46num4_2017/contentsVol46num4_2017.html
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	Herbal medicine is usually made using dry powdered herbs in the form of capsule. Capsule form herbal supplement suffers lower shelf life as compared to compact herbal powder in tablet form. In this study, Diabecine™, a blend of herbal medicine traditionally used as herbal supplement for diabetic patients was selected and transformed into a compressed tablet. Direct compression method and minimal usage of excipients were the aims of this study. By using direct compression, the blend of 40% fine powder herbs and 60% of excipients performed the best and fulfill the pharmaceutical standard. The safety data of microbial and heavy metal testing obtained met the safety requirements for herbal supplement category under the National Pharmaceutical Control Bureau of Malaysia. In conclusion, the tablet formulation of DiabecineTM is suitable to be manufactured by using direct compression method. This research implicates the possibility of producing tablets with high dose of herbal powder by direct compression method.
format	Article
author	Chee, Teh Liam Fadzilah Adibah Abdul Majid, Mohd Cairul Iqbal,
spellingShingle	Chee, Teh Liam Fadzilah Adibah Abdul Majid, Mohd Cairul Iqbal, Development of DiabecineTM tablet and confirmation of its physical properties and pharmaceutical safety analysis
author_facet	Chee, Teh Liam Fadzilah Adibah Abdul Majid, Mohd Cairul Iqbal,
author_sort	Chee, Teh Liam
title	Development of DiabecineTM tablet and confirmation of its physical properties and pharmaceutical safety analysis
title_short	Development of DiabecineTM tablet and confirmation of its physical properties and pharmaceutical safety analysis
title_full	Development of DiabecineTM tablet and confirmation of its physical properties and pharmaceutical safety analysis
title_fullStr	Development of DiabecineTM tablet and confirmation of its physical properties and pharmaceutical safety analysis
title_full_unstemmed	Development of DiabecineTM tablet and confirmation of its physical properties and pharmaceutical safety analysis
title_sort	development of diabecinetm tablet and confirmation of its physical properties and pharmaceutical safety analysis
publisher	Penerbit Universiti Kebangsaan Malaysia
publishDate	2017
url	http://journalarticle.ukm.my/11037/ http://journalarticle.ukm.my/11037/ http://journalarticle.ukm.my/11037/1/12%20Teh%20Liam%20Chee.pdf
first_indexed	2023-09-18T19:59:09Z
last_indexed	2023-09-18T19:59:09Z
_version_	1777406731513495552

Development of DiabecineTM tablet and confirmation of its physical properties and pharmaceutical safety analysis

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