Stem bark of Canarium odontophyllum Miq. (Dabai) as potential source of antimicrobial agent

The objective of this study was to evaluate the antimicrobial potential of methanol, acetone and distilled water stem bark extracts from Canarium odontophyllum against Staphylococcus aureus ATCC 25923, Bacillus cereus ATCC 6633, Escherichia coli ATCC 25932, Pseudomonas aeruginosa ATCC 27853, Acineto...

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Main Authors:	Dayang Fredalina Basri, Noor Fazdilah Mustari, Zafira Ayushah Zainul Alamin, Noraziah Mohammad Zin
Format:	Article
Language:	English
Published:	Penerbit Universiti Kebangsaan Malaysia 2017
Online Access:	http://journalarticle.ukm.my/11452/ http://journalarticle.ukm.my/11452/ http://journalarticle.ukm.my/11452/1/16731-47087-1-SM.pdf

id	ukm-11452
recordtype	eprints
spelling	ukm-114522018-03-14T09:30:37Z http://journalarticle.ukm.my/11452/ Stem bark of Canarium odontophyllum Miq. (Dabai) as potential source of antimicrobial agent Dayang Fredalina Basri, Noor Fazdilah Mustari, Zafira Ayushah Zainul Alamin, Noraziah Mohammad Zin, The objective of this study was to evaluate the antimicrobial potential of methanol, acetone and distilled water stem bark extracts from Canarium odontophyllum against Staphylococcus aureus ATCC 25923, Bacillus cereus ATCC 6633, Escherichia coli ATCC 25932, Pseudomonas aeruginosa ATCC 27853, Acinetobacter baumannii strain sensitive, Candida albicans ATCC 64677, Candida glabrata ATCC 90028, Aspergillus niger and Fusarium solani M2781. The extracts from C. odontophyllum stem bark from 3.125 mg/ml to 25 mg/ml were screened against the tested microorganisms using disc diffusion method. The Minimum inhibitory concentration (MIC) and Minimum Bactericidal Concentration (MBC) of the extracts against susceptible organisms were determined using microbroth dilution method and streak-plate technique, respectively. From the antibacterial screening assay, the growth of S. aureus, B. cereus and A. baumannii were inhibited by methanol extract whereas the acetone extract was capable of inhibiting all the tested microorganisms except E.coli, F. solani and A. niger. The lowest MIC value for methanol extract was against A. baumannii (0.195 mg/ml) whereas its MBC value was twice its MIC value (0.391 mg/ml), indicating that methanol extract was bacteriostatic against A. baumannii. While for acetone extract, S. aureus showed bactericidal effect with equal MIC and MBC values at 0.195 mg/ml. In conclusion, stem bark of C. odontophyllum has the potential to be the source of antibacterial agent and can be exploited as an alternative phytoantimicrobial. Penerbit Universiti Kebangsaan Malaysia 2017 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/11452/1/16731-47087-1-SM.pdf Dayang Fredalina Basri, and Noor Fazdilah Mustari, and Zafira Ayushah Zainul Alamin, and Noraziah Mohammad Zin, (2017) Stem bark of Canarium odontophyllum Miq. (Dabai) as potential source of antimicrobial agent. Jurnal Sains Kesihatan Malaysia, 15 (1). pp. 1-6. ISSN 1675-8161 http://ejournal.ukm.my/jskm/issue/view/635
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	The objective of this study was to evaluate the antimicrobial potential of methanol, acetone and distilled water stem bark extracts from Canarium odontophyllum against Staphylococcus aureus ATCC 25923, Bacillus cereus ATCC 6633, Escherichia coli ATCC 25932, Pseudomonas aeruginosa ATCC 27853, Acinetobacter baumannii strain sensitive, Candida albicans ATCC 64677, Candida glabrata ATCC 90028, Aspergillus niger and Fusarium solani M2781. The extracts from C. odontophyllum stem bark from 3.125 mg/ml to 25 mg/ml were screened against the tested microorganisms using disc diffusion method. The Minimum inhibitory concentration (MIC) and Minimum Bactericidal Concentration (MBC) of the extracts against susceptible organisms were determined using microbroth dilution method and streak-plate technique, respectively. From the antibacterial screening assay, the growth of S. aureus, B. cereus and A. baumannii were inhibited by methanol extract whereas the acetone extract was capable of inhibiting all the tested microorganisms except E.coli, F. solani and A. niger. The lowest MIC value for methanol extract was against A. baumannii (0.195 mg/ml) whereas its MBC value was twice its MIC value (0.391 mg/ml), indicating that methanol extract was bacteriostatic against A. baumannii. While for acetone extract, S. aureus showed bactericidal effect with equal MIC and MBC values at 0.195 mg/ml. In conclusion, stem bark of C. odontophyllum has the potential to be the source of antibacterial agent and can be exploited as an alternative phytoantimicrobial.
format	Article
author	Dayang Fredalina Basri, Noor Fazdilah Mustari, Zafira Ayushah Zainul Alamin, Noraziah Mohammad Zin,
spellingShingle	Dayang Fredalina Basri, Noor Fazdilah Mustari, Zafira Ayushah Zainul Alamin, Noraziah Mohammad Zin, Stem bark of Canarium odontophyllum Miq. (Dabai) as potential source of antimicrobial agent
author_facet	Dayang Fredalina Basri, Noor Fazdilah Mustari, Zafira Ayushah Zainul Alamin, Noraziah Mohammad Zin,
author_sort	Dayang Fredalina Basri,
title	Stem bark of Canarium odontophyllum Miq. (Dabai) as potential source of antimicrobial agent
title_short	Stem bark of Canarium odontophyllum Miq. (Dabai) as potential source of antimicrobial agent
title_full	Stem bark of Canarium odontophyllum Miq. (Dabai) as potential source of antimicrobial agent
title_fullStr	Stem bark of Canarium odontophyllum Miq. (Dabai) as potential source of antimicrobial agent
title_full_unstemmed	Stem bark of Canarium odontophyllum Miq. (Dabai) as potential source of antimicrobial agent
title_sort	stem bark of canarium odontophyllum miq. (dabai) as potential source of antimicrobial agent
publisher	Penerbit Universiti Kebangsaan Malaysia
publishDate	2017
url	http://journalarticle.ukm.my/11452/ http://journalarticle.ukm.my/11452/ http://journalarticle.ukm.my/11452/1/16731-47087-1-SM.pdf
first_indexed	2023-09-18T20:00:23Z
last_indexed	2023-09-18T20:00:23Z
_version_	1777406809204588544

Stem bark of Canarium odontophyllum Miq. (Dabai) as potential source of antimicrobial agent

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