Isolation of carbazole alkaloids and coumarins from Aegle marmelos and Murraya koenigii and their antioxidant properties

In this paper, antioxidant properties of Aegle marmelos (stem bark, leaves) and Murraya koenigii (stem bark, root) were evaluated by 2,2-diphenyl-1-picrylhydrazy (DPPH) free radical scavenging, 2,2’-Azino-bis(3-ethylbenzthiozoline-6-sulfonic acid) (ABTS) decolourisation, cupric reducing antioxidant...

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Main Authors:	Rou, Chian Ng, Nur Kartinee Kassim, Soon, Yunie Yu Yeap, Cheng, Gwendoline Lian Ee, Saiful Latifah Yazan, Khalid Hamid Musa
Format:	Article
Language:	English
Published:	Penerbit Universiti Kebangsaan Malaysia 2018
Online Access:	http://journalarticle.ukm.my/12197/ http://journalarticle.ukm.my/12197/ http://journalarticle.ukm.my/12197/1/14%20Rou%20Chian%20Ng.pdf

id	ukm-12197
recordtype	eprints
spelling	ukm-121972018-10-16T13:32:55Z http://journalarticle.ukm.my/12197/ Isolation of carbazole alkaloids and coumarins from Aegle marmelos and Murraya koenigii and their antioxidant properties Rou, Chian Ng Nur Kartinee Kassim, Soon, Yunie Yu Yeap Cheng, Gwendoline Lian Ee Saiful Latifah Yazan, Khalid Hamid Musa, In this paper, antioxidant properties of Aegle marmelos (stem bark, leaves) and Murraya koenigii (stem bark, root) were evaluated by 2,2-diphenyl-1-picrylhydrazy (DPPH) free radical scavenging, 2,2’-Azino-bis(3-ethylbenzthiozoline-6-sulfonic acid) (ABTS) decolourisation, cupric reducing antioxidant capacity (CUPRAC), ferric reducing antioxidant power (FRAP) and linoleic acid/β-carotene assays. The chloroform extract of Murraya koenigii stem bark was found to possess the highest antioxidant activity in CUPRAC (1490.89 mgTE/g extract). In contrary, the hexane extract from Aegle marmelos leaves exhibited the weakest antioxidant activity in the DPPH assay (81.06 mgTE/g extract). The bioactive compound mahanimbine (7) isolated from the stem bark of Murraya koenigii was found to be the most active antioxidant agent with TEAC of 927.73 and 1649.31 mgTE/g corresponding to the ABTS and CUPRAC assays, respectively, as well as a good lipid peroxidation inhibitor with an inhibitory percentage of 70.95%. These CUPRAC and ABTS assays are the first report for Malaysian Murraya koenigii species. Penerbit Universiti Kebangsaan Malaysia 2018-08 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/12197/1/14%20Rou%20Chian%20Ng.pdf Rou, Chian Ng and Nur Kartinee Kassim, and Soon, Yunie Yu Yeap and Cheng, Gwendoline Lian Ee and Saiful Latifah Yazan, and Khalid Hamid Musa, (2018) Isolation of carbazole alkaloids and coumarins from Aegle marmelos and Murraya koenigii and their antioxidant properties. Sains Malaysiana, 47 (8). pp. 1749-1756. ISSN 0126-6039 http://www.ukm.my/jsm/english_journals/vol47num8_2018/contentsVol47num8_2018.html
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	In this paper, antioxidant properties of Aegle marmelos (stem bark, leaves) and Murraya koenigii (stem bark, root) were evaluated by 2,2-diphenyl-1-picrylhydrazy (DPPH) free radical scavenging, 2,2’-Azino-bis(3-ethylbenzthiozoline-6-sulfonic acid) (ABTS) decolourisation, cupric reducing antioxidant capacity (CUPRAC), ferric reducing antioxidant power (FRAP) and linoleic acid/β-carotene assays. The chloroform extract of Murraya koenigii stem bark was found to possess the highest antioxidant activity in CUPRAC (1490.89 mgTE/g extract). In contrary, the hexane extract from Aegle marmelos leaves exhibited the weakest antioxidant activity in the DPPH assay (81.06 mgTE/g extract). The bioactive compound mahanimbine (7) isolated from the stem bark of Murraya koenigii was found to be the most active antioxidant agent with TEAC of 927.73 and 1649.31 mgTE/g corresponding to the ABTS and CUPRAC assays, respectively, as well as a good lipid peroxidation inhibitor with an inhibitory percentage of 70.95%. These CUPRAC and ABTS assays are the first report for Malaysian Murraya koenigii species.
format	Article
author	Rou, Chian Ng Nur Kartinee Kassim, Soon, Yunie Yu Yeap Cheng, Gwendoline Lian Ee Saiful Latifah Yazan, Khalid Hamid Musa,
spellingShingle	Rou, Chian Ng Nur Kartinee Kassim, Soon, Yunie Yu Yeap Cheng, Gwendoline Lian Ee Saiful Latifah Yazan, Khalid Hamid Musa, Isolation of carbazole alkaloids and coumarins from Aegle marmelos and Murraya koenigii and their antioxidant properties
author_facet	Rou, Chian Ng Nur Kartinee Kassim, Soon, Yunie Yu Yeap Cheng, Gwendoline Lian Ee Saiful Latifah Yazan, Khalid Hamid Musa,
author_sort	Rou, Chian Ng
title	Isolation of carbazole alkaloids and coumarins from Aegle marmelos and Murraya koenigii and their antioxidant properties
title_short	Isolation of carbazole alkaloids and coumarins from Aegle marmelos and Murraya koenigii and their antioxidant properties
title_full	Isolation of carbazole alkaloids and coumarins from Aegle marmelos and Murraya koenigii and their antioxidant properties
title_fullStr	Isolation of carbazole alkaloids and coumarins from Aegle marmelos and Murraya koenigii and their antioxidant properties
title_full_unstemmed	Isolation of carbazole alkaloids and coumarins from Aegle marmelos and Murraya koenigii and their antioxidant properties
title_sort	isolation of carbazole alkaloids and coumarins from aegle marmelos and murraya koenigii and their antioxidant properties
publisher	Penerbit Universiti Kebangsaan Malaysia
publishDate	2018
url	http://journalarticle.ukm.my/12197/ http://journalarticle.ukm.my/12197/ http://journalarticle.ukm.my/12197/1/14%20Rou%20Chian%20Ng.pdf
first_indexed	2023-09-18T20:02:04Z
last_indexed	2023-09-18T20:02:04Z
_version_	1777406915308945408

Isolation of carbazole alkaloids and coumarins from Aegle marmelos and Murraya koenigii and their antioxidant properties

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