Risk factors of gastric premalignant lesion in gastritis patients

Gastric cancer is the second leading cause of cancer-related mortality and the fourth most common cancer globally. Gastric premalignant lesions are well known risk factors for the development of gastric cancer. The purpose of this study was to investigate the risk factors of gastric premalignant les...

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Main Authors:	Siregar, Gontar Alamsyah, Parwati, Ida, Achmad, Tri Hanggono, Syukriani, Yoni Fuadah
Format:	Article
Language:	English
Published:	Penerbit Universiti Kebangsaan Malaysia 2018
Online Access:	http://journalarticle.ukm.my/12204/ http://journalarticle.ukm.my/12204/ http://journalarticle.ukm.my/12204/1/20%20Gontar%20Alamsyah%20Siregar.pdf

id	ukm-12204
recordtype	eprints
spelling	ukm-122042018-10-16T13:26:40Z http://journalarticle.ukm.my/12204/ Risk factors of gastric premalignant lesion in gastritis patients Siregar, Gontar Alamsyah Parwati, Ida Achmad, Tri Hanggono Syukriani, Yoni Fuadah Gastric cancer is the second leading cause of cancer-related mortality and the fourth most common cancer globally. Gastric premalignant lesions are well known risk factors for the development of gastric cancer. The purpose of this study was to investigate the risk factors of gastric premalignant lesion. This cross-sectional study observed gastritis patients at Adam Malik General Hospital, Permata Bunda General Hospital, Universitas Sumatera Utara Hospital, all located in Medan, Indonesia. A total of 120 gastritis patients were included in this study. Patients were interviewed with a questionnaire to obtain demographic data, alcohol intake, smoking status, high salt diet and NSAID use. Diagnosis of Helicobacter pylori infection was made using positive results of the carbon-14 urea breath test (14C-UBT), rapid urease test, and/or immunohistochemistry. Endoscopy and biopsy were conducted to diagnose gastric premalignant lesion. Gastric premalignant lesion diagnosis was made when one or more of the following were present: Chronic atrophic gastritis, intestinal metaplasia, or dysplasia. Data were analysed using SPSS version 22. There were 35/120 (29.2%) of gastritis patients having gastric premalignant lesion. Multivariate analysis has shown that H. pylori infection, patients with family history of gastric cancer, alcohol consumption and Batak ethnic have increased risk to develop gastric premalignant lesion (p<0.05). All these results implied that risk factors of gastric premalignant lesion were H. pylori infection, family history of gastric cancer, alcohol intake and Batak ethnic. Penerbit Universiti Kebangsaan Malaysia 2018-08 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/12204/1/20%20Gontar%20Alamsyah%20Siregar.pdf Siregar, Gontar Alamsyah and Parwati, Ida and Achmad, Tri Hanggono and Syukriani, Yoni Fuadah (2018) Risk factors of gastric premalignant lesion in gastritis patients. Sains Malaysiana, 47 (8). pp. 1811-1818. ISSN 0126-6039 http://www.ukm.my/jsm/english_journals/vol47num8_2018/contentsVol47num8_2018.html
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	Gastric cancer is the second leading cause of cancer-related mortality and the fourth most common cancer globally. Gastric premalignant lesions are well known risk factors for the development of gastric cancer. The purpose of this study was to investigate the risk factors of gastric premalignant lesion. This cross-sectional study observed gastritis patients at Adam Malik General Hospital, Permata Bunda General Hospital, Universitas Sumatera Utara Hospital, all located in Medan, Indonesia. A total of 120 gastritis patients were included in this study. Patients were interviewed with a questionnaire to obtain demographic data, alcohol intake, smoking status, high salt diet and NSAID use. Diagnosis of Helicobacter pylori infection was made using positive results of the carbon-14 urea breath test (14C-UBT), rapid urease test, and/or immunohistochemistry. Endoscopy and biopsy were conducted to diagnose gastric premalignant lesion. Gastric premalignant lesion diagnosis was made when one or more of the following were present: Chronic atrophic gastritis, intestinal metaplasia, or dysplasia. Data were analysed using SPSS version 22. There were 35/120 (29.2%) of gastritis patients having gastric premalignant lesion. Multivariate analysis has shown that H. pylori infection, patients with family history of gastric cancer, alcohol consumption and Batak ethnic have increased risk to develop gastric premalignant lesion (p<0.05). All these results implied that risk factors of gastric premalignant lesion were H. pylori infection, family history of gastric cancer, alcohol intake and Batak ethnic.
format	Article
author	Siregar, Gontar Alamsyah Parwati, Ida Achmad, Tri Hanggono Syukriani, Yoni Fuadah
spellingShingle	Siregar, Gontar Alamsyah Parwati, Ida Achmad, Tri Hanggono Syukriani, Yoni Fuadah Risk factors of gastric premalignant lesion in gastritis patients
author_facet	Siregar, Gontar Alamsyah Parwati, Ida Achmad, Tri Hanggono Syukriani, Yoni Fuadah
author_sort	Siregar, Gontar Alamsyah
title	Risk factors of gastric premalignant lesion in gastritis patients
title_short	Risk factors of gastric premalignant lesion in gastritis patients
title_full	Risk factors of gastric premalignant lesion in gastritis patients
title_fullStr	Risk factors of gastric premalignant lesion in gastritis patients
title_full_unstemmed	Risk factors of gastric premalignant lesion in gastritis patients
title_sort	risk factors of gastric premalignant lesion in gastritis patients
publisher	Penerbit Universiti Kebangsaan Malaysia
publishDate	2018
url	http://journalarticle.ukm.my/12204/ http://journalarticle.ukm.my/12204/ http://journalarticle.ukm.my/12204/1/20%20Gontar%20Alamsyah%20Siregar.pdf
first_indexed	2023-09-18T20:02:05Z
last_indexed	2023-09-18T20:02:05Z
_version_	1777406916191846400

Risk factors of gastric premalignant lesion in gastritis patients

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