Brain activations evoked by passive and active listening: a preliminary study on multiple subjects

A functional magnetic resonance imaging (fMRI) study was conducted on 4 healthy male and female subjects to investigate brain activation during passive and active listening. Two different experimental conditions were separately used in this study. The first condition requires the subjects to list...

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Main Authors:	Ahmad Nazlim Yusoff, Mazlyfarina Mohamad, Mohd Mahadir Ayob, Mohd Harith Hashim
Format:	Article
Language:	English
Published:	Penerbit UKM 2008
Online Access:	http://journalarticle.ukm.my/1403/ http://journalarticle.ukm.my/1403/ http://journalarticle.ukm.my/1403/1/Ahmad%20Nazlim%20Yusoff%20et%20al..pdf

id	ukm-1403
recordtype	eprints
spelling	ukm-14032016-12-14T06:29:24Z http://journalarticle.ukm.my/1403/ Brain activations evoked by passive and active listening: a preliminary study on multiple subjects Ahmad Nazlim Yusoff, Mazlyfarina Mohamad, Mohd Mahadir Ayob, Mohd Harith Hashim, A functional magnetic resonance imaging (fMRI) study was conducted on 4 healthy male and female subjects to investigate brain activation during passive and active listening. Two different experimental conditions were separately used in this study. The first condition requires the subjects to listen to a simple arithmetic instruction (e.g. one-plus-two-plus-three-plus-four) – passive listening. In the second condition, the subjects were given the same series of arithmetic instruction and were required to listen and perform the calculation – active listening. The data were then analysed using the Statistical Parametric Mapping (SPM5) and the MATLAB 7.4 (R2007a) programming softwares. The results obtained from the fixed (FFX) and random effects analyses (RFX) show that the active-state signal intensity was significantly higher (p < 0.05) than the resting-state signal intensity for both conditions. The results also indicate significant differences (p < 0.001) in brain activation between passive and active listening. The activated cortical regions during passive listening, as obtained from the FFX of the first condition is symmetrical in the left and right temporal and frontal lobes covering the cortical auditory areas. However, for the second condition, which was active listening, more activation occurs in the left hemisphere with a reduction in the number of activated voxels and their signal intensity in the right hemisphere. Activation mainly occurs in the middle temporal gyrus, precentral gyrus, middle frontal gyrus, superior temporal gyrus and several other areas in the frontal lobes. The point of maximum signal intensity has been shifted to a new coordinates during active listening. It is also observed that the magnetic resonance signal intensity and the number of activated voxel in the right and left superior temporal lobes for the second condition have been reduced as compared to that of the first condition. The results obtained strongly suggest the existence of functional specialisation. The results also indicate different networks for the two conditions. These networks clearly pertain to the existence of functional Jurnal Sains Kesihatan Malaysia 6 (1) 2008: 35-6036 connectivity between activation areas during listening and listening while performing a simple arithmetic task. Penerbit UKM 2008-06 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/1403/1/Ahmad%20Nazlim%20Yusoff%20et%20al..pdf Ahmad Nazlim Yusoff, and Mazlyfarina Mohamad, and Mohd Mahadir Ayob, and Mohd Harith Hashim, (2008) Brain activations evoked by passive and active listening: a preliminary study on multiple subjects. Jurnal Sains Kesihatan Malaysia, 6 (1). pp. 35-60. ISSN 1675-8161 http://www.fskb.ukm.my/fskbold/jurnal.html
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	A functional magnetic resonance imaging (fMRI) study was conducted on 4 healthy male and female subjects to investigate brain activation during passive and active listening. Two different experimental conditions were separately used in this study. The first condition requires the subjects to listen to a simple arithmetic instruction (e.g. one-plus-two-plus-three-plus-four) – passive listening. In the second condition, the subjects were given the same series of arithmetic instruction and were required to listen and perform the calculation – active listening. The data were then analysed using the Statistical Parametric Mapping (SPM5) and the MATLAB 7.4 (R2007a) programming softwares. The results obtained from the fixed (FFX) and random effects analyses (RFX) show that the active-state signal intensity was significantly higher (p < 0.05) than the resting-state signal intensity for both conditions. The results also indicate significant differences (p < 0.001) in brain activation between passive and active listening. The activated cortical regions during passive listening, as obtained from the FFX of the first condition is symmetrical in the left and right temporal and frontal lobes covering the cortical auditory areas. However, for the second condition, which was active listening, more activation occurs in the left hemisphere with a reduction in the number of activated voxels and their signal intensity in the right hemisphere. Activation mainly occurs in the middle temporal gyrus, precentral gyrus, middle frontal gyrus, superior temporal gyrus and several other areas in the frontal lobes. The point of maximum signal intensity has been shifted to a new coordinates during active listening. It is also observed that the magnetic resonance signal intensity and the number of activated voxel in the right and left superior temporal lobes for the second condition have been reduced as compared to that of the first condition. The results obtained strongly suggest the existence of functional specialisation. The results also indicate different networks for the two conditions. These networks clearly pertain to the existence of functional Jurnal Sains Kesihatan Malaysia 6 (1) 2008: 35-6036 connectivity between activation areas during listening and listening while performing a simple arithmetic task.
format	Article
author	Ahmad Nazlim Yusoff, Mazlyfarina Mohamad, Mohd Mahadir Ayob, Mohd Harith Hashim,
spellingShingle	Ahmad Nazlim Yusoff, Mazlyfarina Mohamad, Mohd Mahadir Ayob, Mohd Harith Hashim, Brain activations evoked by passive and active listening: a preliminary study on multiple subjects
author_facet	Ahmad Nazlim Yusoff, Mazlyfarina Mohamad, Mohd Mahadir Ayob, Mohd Harith Hashim,
author_sort	Ahmad Nazlim Yusoff,
title	Brain activations evoked by passive and active listening: a preliminary study on multiple subjects
title_short	Brain activations evoked by passive and active listening: a preliminary study on multiple subjects
title_full	Brain activations evoked by passive and active listening: a preliminary study on multiple subjects
title_fullStr	Brain activations evoked by passive and active listening: a preliminary study on multiple subjects
title_full_unstemmed	Brain activations evoked by passive and active listening: a preliminary study on multiple subjects
title_sort	brain activations evoked by passive and active listening: a preliminary study on multiple subjects
publisher	Penerbit UKM
publishDate	2008
url	http://journalarticle.ukm.my/1403/ http://journalarticle.ukm.my/1403/ http://journalarticle.ukm.my/1403/1/Ahmad%20Nazlim%20Yusoff%20et%20al..pdf
first_indexed	2023-09-18T19:33:13Z
last_indexed	2023-09-18T19:33:13Z
_version_	1777405099654512640

Brain activations evoked by passive and active listening: a preliminary study on multiple subjects

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